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Graph-based Retrieval-Augmented Generation (GraphRAG) extends traditional RAG by using knowledge graphs (KGs) to give large language models (LLMs) a structured, semantically coherent context, yielding more grounded answers. However,…

Artificial Intelligence · Computer Science 2026-04-28 Zhuoling Li , Ha Linh Hong Tran Nguyen , Valeria Bladinieres , Maxim Romanovsky

Unlocking deep and interpretable biological reasoning from complex genomic data remains a major AI challenge limiting scientific progress. While current DNA foundation models excel at representing sequences, they struggle with multi-step…

Graph-based retrieval-augmented generation (RAG) enables large language models (LLMs) to ground responses with structured external knowledge from up-to-date knowledge graphs (KGs) and reduce hallucinations. However, LLMs often rely on a…

Computation and Language · Computer Science 2025-07-01 Deyu Zou , Yongqiang Chen , Mufei Li , Siqi Miao , Chenxi Liu , Bo Han , James Cheng , Pan Li

Integrating Large Language Models (LLMs) in Intelligent Tutoring Systems (ITS) presents transformative opportunities for personalized education. However, current implementations face two critical challenges: maintaining factual accuracy and…

Computation and Language · Computer Science 2025-02-13 Chenxi Dong , Yimin Yuan , Kan Chen , Shupei Cheng , Chujie Wen

Retrieval-augmented generation (RAG) is a powerful technique that enhances downstream task execution by retrieving additional information, such as knowledge, skills, and tools from external sources. Graph, by its intrinsic "nodes connected…

Retrieval-Augmented Generation (RAG) extends large language models (LLMs) beyond parametric knowledge, yet it is unclear when iterative retrieval-reasoning loops meaningfully outperform static RAG, particularly in scientific domains with…

Computation and Language · Computer Science 2026-05-05 Mahdi Astaraki , Mohammad Arshi Saloot , Ali Shiraee Kasmaee , Hamidreza Mahyar , Soheila Samiee

Retrieval-Augmented Generation (RAG) aims to reduce hallucination by grounding answers in retrieved evidence, yet hallucinated answers remain common even when relevant documents are available. Existing evaluations focus on answer-level or…

Computation and Language · Computer Science 2026-05-21 Passant Elchafei , Monorama Swain , Shahed Masoudian , Markus Schedl

Retrieval-augmented generation (RAG) has demonstrated its ability to enhance Large Language Models (LLMs) by integrating external knowledge sources. However, multi-hop questions, which require the identification of multiple knowledge…

Machine Learning · Computer Science 2026-04-28 Yuchen Yan , Peiyan Zhang , Zhihua Liu , Hao Wang , Yatao Bian , Weiming Li , Xiaoshuai Hao

We present MA-RAG, a Multi-Agent framework for Retrieval-Augmented Generation (RAG) that addresses the inherent ambiguities and reasoning challenges in complex information-seeking tasks. Unlike conventional RAG methods that rely on…

Computation and Language · Computer Science 2025-10-14 Thang Nguyen , Peter Chin , Yu-Wing Tai

Retrieval-augmented generation has gained significant attention due to its ability to integrate relevant external knowledge, enhancing the accuracy and reliability of the LLMs' responses. Most of the existing methods apply a dynamic…

Computation and Language · Computer Science 2025-01-13 Liang Xiao , Wen Dai , Shuai Chen , Bin Qin , Chongyang Shi , Haopeng Jing , Tianyu Guo

Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…

Computation and Language · Computer Science 2025-05-27 Yuxing Lu , Gecheng Fu , Wei Wu , Xukai Zhao , Sin Yee Goi , Jinzhuo Wang

Knowledge graph question answering (KGQA) presents significant challenges due to the structural and semantic variations across input graphs. Existing works rely on Large Language Model (LLM) agents for graph traversal and retrieval; an…

Computation and Language · Computer Science 2025-07-08 Costas Mavromatis , Soji Adeshina , Vassilis N. Ioannidis , Zhen Han , Qi Zhu , Ian Robinson , Bryan Thompson , Huzefa Rangwala , George Karypis

Increasing evidence has shown that gene-gene interactions have important effects on biological processes of human diseases. Due to the high dimensionality of genetic measurements, existing interaction analysis methods usually suffer from a…

Methodology · Statistics 2021-01-11 Xing Qin , Shuangge Ma , Mengyun Wu

Recent advances in retrieval-augmented generation (RAG) furnish large language models (LLMs) with iterative retrievals of relevant information to handle complex multi-hop questions. These methods typically alternate between LLM reasoning…

Computation and Language · Computer Science 2025-05-27 Rui Li , Quanyu Dai , Zeyu Zhang , Xu Chen , Zhenhua Dong , Ji-Rong Wen

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Large language models (LLMs) excel on general tasks yet still hallucinate in high-barrier domains such as pathology. Prior work often relies on domain fine-tuning, which neither expands the knowledge boundary nor enforces evidence-grounded…

Computation and Language · Computer Science 2025-10-13 Deshui Yu , Yizhi Wang , Saihui Jin , Taojie Zhu , Fanyi Zeng , Wen Qian , Zirui Huang , Jingli Ouyang , Jiameng Li , Zhen Song , Tian Guan , Yonghong He

Graph Retrieval-Augmented Generation (GraphRAG) has shown great effectiveness in enhancing the reasoning abilities of LLMs by leveraging graph structures for knowledge representation and modeling complex real-world relationships. However,…

Machine Learning · Computer Science 2026-01-28 Chuanyue Yu , Kuo Zhao , Yuhan Li , Heng Chang , Mingjian Feng , Xiangzhe Jiang , Yufei Sun , Jia Li , Yuzhi Zhang , Jianxin Li , Ziwei Zhang

Despite recent progress, Graphic User Interface (GUI) agents powered by Large Language Models (LLMs) struggle with complex mobile tasks due to limited app-specific knowledge. While UI Transition Graphs (UTGs) offer structured navigation…

Multimodal fusion benefits disease diagnosis by providing a more comprehensive perspective. Developing algorithms is challenging due to data heterogeneity and the complex within- and between-modality associations. Deep-network-based…

Neurons and Cognition · Quantitative Biology 2020-06-18 Wenxing Hu , Xianghe Meng , Yuntong Bai , Aiying Zhang , Biao Cai , Gemeng Zhang , Tony W. Wilson , Julia M. Stephen , Vince D. Calhoun , Yu-Ping Wang

Despite their remarkable capabilities, large language models (LLMs) often produce responses containing factual inaccuracies due to their sole reliance on the parametric knowledge they encapsulate. Retrieval-Augmented Generation (RAG), an ad…

Computation and Language · Computer Science 2023-10-19 Akari Asai , Zeqiu Wu , Yizhong Wang , Avirup Sil , Hannaneh Hajishirzi
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