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Retrieval-Augmented Generation (RAG) has become a powerful and widely used approach for improving large language models by grounding generation in retrieved evidence. However, RAG systems still produce incorrect answers in many cases. Why…

Computation and Language · Computer Science 2026-05-15 Kai Guo , Xinnan Dai , Zhibo Zhang , Nuohan Lin , Shenglai Zeng , Jie Ren , Haoyu Han , Jiliang Tang

The intrinsic complexity of human biology presents ongoing challenges to scientific understanding. Researchers collaborate across disciplines to expand our knowledge of the biological interactions that define human life. AI methodologies…

Despite the impressive advancements of Large Language Models (LLMs) in generating text, they are often limited by the knowledge contained in the input and prone to producing inaccurate or hallucinated content. To tackle these issues,…

Information Retrieval · Computer Science 2024-05-29 Yu Wang , Nedim Lipka , Ruiyi Zhang , Alexa Siu , Yuying Zhao , Bo Ni , Xin Wang , Ryan Rossi , Tyler Derr

In domains such as materials science, biomedicine, and finance, high-stakes deployment of large language models (LLMs) requires injecting private, domain-specific knowledge that is proprietary, fast-evolving, and under-represented in public…

Computation and Language · Computer Science 2026-04-15 Rongji Li , Jian Xu , Yi Chen , Xueqing Chen , Yisheng Yang , Jiayi Wang , Xingyu Chen , Chunyu Xie , Dawei Leng , Xu-Yao Zhang

Given a graph with textual attributes, we enable users to `chat with their graph': that is, to ask questions about the graph using a conversational interface. In response to a user's questions, our method provides textual replies and…

Machine Learning · Computer Science 2024-05-28 Xiaoxin He , Yijun Tian , Yifei Sun , Nitesh V. Chawla , Thomas Laurent , Yann LeCun , Xavier Bresson , Bryan Hooi

Retrieval-Augmented Generation (RAG) has recently been extended to multimodal settings, connecting multimodal large language models (MLLMs) with vast corpora of external knowledge such as multimodal knowledge graphs (MMKGs). Despite their…

Computation and Language · Computer Science 2026-04-14 Hyeongcheol Park , Jiyoung Seo , Jaewon Mun , Hogun Park , Wonmin Byeon , Sung June Kim , Hyeonsoo Im , JeungSub Lee , Sangpil Kim

Graph-based retrieval-augmented generation (Graph-based RAG) has demonstrated significant potential in enhancing Large Language Models (LLMs) with structured knowledge. However, existing methods face three critical challenges: Inaccurate…

Machine Learning · Computer Science 2026-03-18 Yubo Wang , Haoyang Li , Fei Teng , Lei Chen

Retrieval-Augmented Generation (RAG) has emerged as an effective paradigm for expanding the knowledge capacity of Multimodal Large Language Models (MLLMs) by incorporating external knowledge sources into the generation process, and has been…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xu Yuan , Liangbo Ning , Qingqing Ye , Wenqi Fan , Qing Li

Retrieval-augmented generation (RAG) improves large language model reliability by grounding generated responses in external evidence. However, RAG performance depends on the relevance of retrieved passages, the quality of evidence ranking,…

Information Retrieval · Computer Science 2026-05-05 Fariba Afrin Irany , Sampson Akwafuo

Retrieval-Augmented Generation (RAG) empowers Large Language Models (LLMs) to dynamically integrate external knowledge during inference, improving their factual accuracy and adaptability. However, adversaries can inject poisoned external…

Artificial Intelligence · Computer Science 2026-01-13 Hanyu Zhu , Lance Fiondella , Jiawei Yuan , Kai Zeng , Long Jiao

Biological networks provide insight into the complex organization of biological processes in a cell at the system level. They are an effective tool for understanding the comprehensive map of functional interactions, finding the functional…

Molecular Networks · Quantitative Biology 2017-09-14 Somaye Hashemifar

Large Language Models (LLMs) are proficient at generating coherent and contextually relevant text but face challenges when addressing knowledge-intensive queries in domain-specific and factual question-answering tasks. Retrieval-augmented…

Information Retrieval · Computer Science 2024-10-08 Garima Agrawal , Tharindu Kumarage , Zeyad Alghamdi , Huan Liu

Retrieval-Augmented Generation (RAG) effectively enhances Large Language Models (LLMs) by incorporating retrieved external knowledge into the generation process. Reasoning models improve LLM performance in multi-hop QA tasks, which require…

Computation and Language · Computer Science 2026-01-21 Guo Chen , Junjie Huang , Huaijin Xie , Fei Sun , Tao Jia

Large Language Models (LLMs) demonstrate potential in the field of scientific idea generation. However, the generated results often lack controllable academic context and traceable inspiration pathways. To bridge this gap, this paper…

Artificial Intelligence · Computer Science 2026-02-27 Pengzhen Xie , Huizhi Liang

Retrieval-Augmented Generation (RAG) enhances the response quality and domain-specific performance of large language models (LLMs) by incorporating external knowledge to combat hallucinations. In recent research, graph structures have been…

Information Retrieval · Computer Science 2025-12-17 Hao Hu , Yifan Feng , Ruoxue Li , Rundong Xue , Xingliang Hou , Zhiqiang Tian , Yue Gao , Shaoyi Du

Since large language models (LLMs) have a tendency to generate factually inaccurate output, retrieval-augmented generation (RAG) has gained significant attention as a key means to mitigate this downside of harnessing only LLMs. However,…

Computation and Language · Computer Science 2025-12-18 Youmin Ko , Sungjong Seo , Hyunjoon Kim

Despite the remarkable progress of Large Language Models (LLMs), their performance in question answering (QA) remains limited by the lack of domain-specific and up-to-date knowledge. Retrieval-Augmented Generation (RAG) addresses this…

Information Retrieval · Computer Science 2025-09-17 Yaodong Su , Yixiang Fang , Yingli Zhou , Quanqing Xu , Chuanhui Yang

Retrieval-Augmented Generation (RAG) has emerged as a powerful framework for enhancing the capabilities of Large Language Models (LLMs) by integrating retrieval-based methods with generative models. As external knowledge repositories…

Computation and Language · Computer Science 2025-11-14 Shuyi Liu , Yuming Shang , Xi Zhang

Understanding how molecular alterations propagate across biological systems to drive disease remains a central challenge. Although high-throughput profiling enables comprehensive characterization of tumor states, most models neglect…

Quantitative Methods · Quantitative Biology 2026-05-11 Kyle Higgins , Guadalupe Gonzalez , Dennis Veselkov , Ivan Laponogov , Kirill Veselkov

Retrieval Augmented Generation (RAG) complements the knowledge of Large Language Models (LLMs) by leveraging external information to enhance response accuracy for queries. This approach is widely applied in several fields by taking its…