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With fully leveraging the value of unlabeled data, semi-supervised medical image segmentation algorithms significantly reduces the limitation of limited labeled data, achieving a significant improvement in accuracy. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Jialu Zhou , Dianxi Shi , Shaowu Yang , Chunping Qiu , Luoxi Jing , Mengzhu Wang

Weakly supervised whole slide image classification is a key task in computational pathology, which involves predicting a slide-level label from a set of image patches constituting the slide. Constructing models to solve this task involves…

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

This paper presents a simple yet effective two-stage framework for semi-supervised medical image segmentation. Unlike prior state-of-the-art semi-supervised segmentation methods that predominantly rely on pseudo supervision directly on…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Huimin Wu , Xiaomeng Li , Kwang-Ting Cheng

Scarcity of labeled data has motivated the development of semi-supervised learning methods, which learn from large portions of unlabeled data alongside a few labeled samples. Consistency Regularization between model's predictions under…

Computer Vision and Pattern Recognition · Computer Science 2020-07-16 Aamir Mustafa , Rafal K. Mantiuk

Traditional supervised learning tasks require a label for every instance in the training set, but in many real-world applications, labels are only available for collections (bags) of instances. This problem setting, known as multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Georg Wölflein , Lucie Charlotte Magister , Pietro Liò , David J. Harrison , Ognjen Arandjelović

Pixel-wise segmentation is one of the most data and annotation hungry tasks in our field. Providing representative and accurate annotations is often mission-critical especially for challenging medical applications. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Simon Reiß , Constantin Seibold , Alexander Freytag , Erik Rodner , Rainer Stiefelhagen

Learning segmentation from noisy labels is an important task for medical image analysis due to the difficulty in acquiring highquality annotations. Most existing methods neglect the pixel correlation and structural prior in segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Shuailin Li , Zhitong Gao , Xuming He

In computational pathology, weak supervision has become the standard for deep learning due to the gigapixel scale of WSIs and the scarcity of pixel-level annotations, with Multiple Instance Learning (MIL) established as the principal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Andreas Lolos , Theofilos Christodoulou , Aris L. Moustakas , Stergios Christodoulidis , Maria Vakalopoulou

Histopathological whole slide image (WSI) analysis with deep learning has become a research focus in computational pathology. The current paradigm is mainly based on multiple instance learning (MIL), in which approaches with Transformer as…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hongbo Chu , Qiehe Sun , Jiawen Li , Yuxuan Chen , Lizhong Zhang , Tian Guan , Anjia Han , Yonghong He

Multiple instance learning (MIL) has been increasingly used in the classification of histopathology whole slide images (WSIs). However, MIL approaches for this specific classification problem still face unique challenges, particularly those…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Hongrun Zhang , Yanda Meng , Yitian Zhao , Yihong Qiao , Xiaoyun Yang , Sarah E. Coupland , Yalin Zheng

Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

Semi-supervised learning has substantially advanced medical image segmentation since it alleviates the heavy burden of acquiring the costly expert-examined annotations. Especially, the consistency-based approaches have attracted more…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Zhe Xu , Yixin Wang , Donghuan Lu , Lequan Yu , Jiangpeng Yan , Jie Luo , Kai Ma , Yefeng Zheng , Raymond Kai-yu Tong

This paper introduces the unsupervised assignment flow that couples the assignment flow for supervised image labeling with Riemannian gradient flows for label evolution on feature manifolds. The latter component of the approach encompasses…

Machine Learning · Computer Science 2019-12-17 Artjom Zern , Matthias Zisler , Stefania Petra , Christoph Schnörr

While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Honglin Li , Chenglu Zhu , Yunlong Zhang , Yuxuan Sun , Zhongyi Shui , Wenwei Kuang , Sunyi Zheng , Lin Yang

Image harmonization is a crucial technique in image composition that aims to seamlessly match the background by adjusting the foreground of composite images. Current methods adopt either global-level or pixel-level feature matching.…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Haoxing Chen , Yaohui Li , Zhangxuan Gu , Zhuoer Xu , Jun Lan , Huaxiong Li

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

In fine-grained road scene understanding, semantic segmentation plays a crucial role in enabling vehicles to perceive and comprehend their surroundings. By assigning a specific class label to each pixel in an image, it allows for precise…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Yuting Hong , Yongkang Wu , Hui Xiao , Huazheng Hao , Xiaojie Qiu , Baochen Yao , Chengbin Peng

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

Is self-supervised deep learning (DL) for medical image analysis already a serious alternative to the de facto standard of end-to-end trained supervised DL? We tackle this question for medical image classification, with a particular focus…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Maximilian Nielsen , Laura Wenderoth , Thilo Sentker , René Werner