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We present a unified theoretical model relating stochastic microscopic epidemic dynamics with macroscopic non-linear population behavior. Utilizing the Doi-Peliti formalism, we model the pathogen as a gauge mediator field coupled to…

Populations and Evolution · Quantitative Biology 2026-04-02 Jose de Jesus Bernal-Alvarado , David Delepine

Classical compartmental models of epidemiology rely on well-mixed, local interaction approximations that fail to capture the heavy-tailed burst dynamics and long-range spatial correlations observed in real-world outbreaks. While fractional…

Statistical Mechanics · Physics 2026-03-31 Jose Jesus Bernal-Alvarado , David Delepine

We propose an extension of the classical susceptible infectious recovered (SIR) model that incorporates the effects of spatial propagation of an epidemic through a small number of additional compartments. The model is designed to capture…

Numerical Analysis · Mathematics 2026-03-02 M. Soledad Aronna , Mariana Bergonzi , Ernesto Kofman

Infectious disease superspreading caused by heterogeneity in contact behavior has been observed to be an important determinant of epidemic dynamics and size in both empirical and theoretical settings. However, it has also been observed that…

Populations and Evolution · Quantitative Biology 2026-01-27 Ari S. Freedman , Bjarke F. Nielsen , Maximillian M. Nguyen , Laurent Hébert-Dufresne , Simon A. Levin

We show that precise knowledge of epidemic transmission parameters is not required to build an informative model of the spread of disease. We propose a detailed model of the topology of the contact network under various external control…

Populations and Evolution · Quantitative Biology 2020-06-15 Michael Small , David Cavanagh

We make a retrospective review on various control measures taken by 127 countries/territories during the first wave of COVID-19 pandemic until July 7, 2020, and evaluate their impacts on the epidemic dynamics quantitatively. The SEIR-QD…

Populations and Evolution · Quantitative Biology 2023-09-25 Dongyan Zhang , Wuyue Yang , Wanqi Wen , Liangrong Peng , Changjingn Zhuge , Liu Hong

This paper extends the canonical model of epidemiology, the SIRD model, to allow for time-varying parameters for real-time measurement and prediction of the trajectory of the Covid-19 pandemic. Time variation in model parameters is captured…

Econometrics · Economics 2023-02-01 Cem Cakmakli , Yasin Simsek

Obtaining accurate forecasts for the evolution of epidemic outbreaks from deterministic compartmental models represents a major theoretical challenge. Recently, it has been shown that these models typically exhibit trajectories' degeneracy,…

Covid-19 is one of the most dreaded pandemics/epidemics in the world threatening the human population. The dynamics of this pandemic is quite complicated and prediction of pandemic states often fails. In this work, we study and correlate…

Populations and Evolution · Quantitative Biology 2021-10-06 Jyoti Bhadana , R. K. Brojen Singh

Objective: COVID-19 has spread worldwide and made a huge influence across the world. Modeling the infectious spread situation of COVID-19 is essential to understand the current condition and to formulate intervention measurements.…

Machine Learning · Computer Science 2023-06-23 Ruhan Liu , Jiajia Li , Yang Wen , Huating Li , Ping Zhang , Bin Sheng , David Dagan Feng

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

This paper presents a novel time-space SIR (Susceptible-Infected-Recovered) model for simulating infectious disease dynamics in two interconnected regions. The model is formulated as a coupled reaction-diffusion system with boundary…

Analysis of PDEs · Mathematics 2026-05-13 Omar Elamraoui , Jawad Salhi , Abderrahim Zafrar

In this work we performed a numerical study of an epidemic model that mimics the endemic state of whooping cough in the pre-vaccine era. We considered a stochastic SIR model on dynamical networks that involve local and global contacts among…

Physics and Society · Physics 2015-06-09 Martin Dottori , Gabriel Fabricius

The spread of infectious diseases crucially depends on the pattern of contacts among individuals. Knowledge of these patterns is thus essential to inform models and computational efforts. Few empirical studies are however available that…

We present an exact analytical solution to a one-dimensional model of the Susceptible-Infected-Recovered (SIR) epidemic type, with infection rates dependent on nearest-neighbor occupations. We use a quantum mechanical approach, transforming…

Statistical Mechanics · Physics 2015-05-30 H. Thomas Williams , Irina Mazilu , Dan Mazilu

It is increasingly important to understand the spatial dynamics of epidemics. While there are numerous mathematical models of epidemics, there is a scarcity of physical systems with sufficiently well-controlled parameters to allow…

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

Methodology · Statistics 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

We introduce a kinetic framework for modeling the time evolution of the statistical distributions of the population densities in the three compartments of susceptible, infectious, and recovered individuals, under epidemic spreading driven…

Analysis of PDEs · Mathematics 2025-12-16 Giorgio Martalò , Giuseppe Toscani , Mattia Zanella

In the recent COVID-19 pandemic we assisted at a sequence of epidemic waves intertwined by anomalous fade-outs with periods of low but persistent epidemic prevalence. These long-living epidemic states complicate epidemic control and…

Physics and Society · Physics 2025-08-27 Javier Aguilar , Beatriz Arregui García , Raúl Toral , Sandro Meloni , Jose J. Ramasco

The worldwide COVID-19 pandemic has led to a significant growth of interest in the development of mathematical models that allow to describe effects such as social distancing measures, the development of vaccines, and mutations. Several of…

Soft Condensed Matter · Physics 2023-07-04 Michael te Vrugt , Julian Jeggle , Raphael Wittkowski
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