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In this work, we adapt the epidemiological SIR model to study the evolution of the dissemination of COVID-19 in Germany and Brazil (nationally, in the State of Paraiba, and in the City of Campina Grande). We prove the well posedness and the…

Populations and Evolution · Quantitative Biology 2022-04-20 Adriano A. Batista , Severino Horácio da Silva

In this work, we aim to formalize a novel scientific machine learning framework to reconstruct the hidden dynamics of the transmission rate, whose inaccurate extrapolation can significantly impair the quality of the epidemic forecasts, by…

Quantitative Methods · Quantitative Biology 2024-10-16 Giovanni Ziarelli , Stefano Pagani , Nicola Parolini , Francesco Regazzoni , Marco Verani

OBJECTIVES: to describe the first wave of the COVID-19 pandemic with a focus on undetected cases and to evaluate different post-lockdown scenarios. DESIGN: the study introduces a SEIR compartmental model, taking into account the…

Populations and Evolution · Quantitative Biology 2021-06-03 Nicola Picchiotti , Monica Salvioli , Elena Zanardini , Francesco Missale

The growing literature on the propagation of COVID-19 relies on various dynamic SIR-type models (Susceptible-Infected-Recovered) which yield model-dependent results. For transparency and ease of comparing the results, we introduce a common…

Populations and Evolution · Quantitative Biology 2020-06-19 Christian Gourieroux , Joann Jasiak

Contacts between people are the absolute drivers of contagious respiratory infections. For this reason, limiting and tracking contacts is a key strategy for the control of the COVID-19 epidemic. Digital contact tracing has been proposed as…

Computers and Society · Computer Science 2022-12-01 Chiara Boldrini , Andrea Passarella , Marco Conti

In this work we analyze mathematically the consequences and effectiveness of strategies to control an epidemic in the framework of classical SEIR models with multiple parallel infectious stages. We define the mathematical concept of a…

Dynamical Systems · Mathematics 2023-08-17 Annibal Figueiredo , Tarcısio Marciano da Rocha Filho

We tackle limitations of ordinary differential equation-driven Susceptible-Infections-Removed (SIR) models and their extensions that have recently be employed for epidemic nowcasting and forecasting. In particular, we deal with challenges…

Computation · Statistics 2026-02-10 Angelos Alexopoulos , Paul Birrell , Daniela De Angelis

In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…

Populations and Evolution · Quantitative Biology 2020-05-22 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model with a contact rate that fluctuates seasonally. Through the use of a nonlinear, stochastic projection, we are able to analytically determine the…

Populations and Evolution · Quantitative Biology 2013-09-11 Eric Forgoston , Ira B. Schwartz

We present a modelling framework for the spreading of epidemics on temporal networks from which both the individual-based and pair-based models can be recovered. The proposed temporal pair-based model that is systematically derived from…

Physics and Society · Physics 2020-11-17 Rory Humphries , Kieran Mulchrone , Jamie Tratalos , Simon More , Philipp Hövel

The last decade saw the advent of increasingly realistic epidemic models that leverage on the availability of highly detailed census and human mobility data. Data-driven models aim at a granularity down to the level of households or single…

Populations and Evolution · Quantitative Biology 2011-08-10 Nicola Perra , Duygu Balcan , Bruno Gonçalves , Alessandro Vespignani

The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

In this paper we propose a data-driven model for the spread of SARS-CoV-2 and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and minimize the economic costs associated with…

Optimization and Control · Mathematics 2021-05-21 Mikhail Hayhoe , Francisco Barreras , Victor M. Preciado

We investigate the SIR epidemic on a dynamic inhomogeneous Erd\H{o}s-R\'enyi random graph, in which vertices are of one of $k$ types and in which edges appear and disappear independently of each other. We establish a functional law of large…

Probability · Mathematics 2024-04-22 Yuanfei Huang , Adrian Röllin

We investigate the information-theoretical limits of inference tasks in epidemic spreading on graphs in the thermodynamic limit. The typical inference tasks consist in computing observables of the posterior distribution of the epidemic…

Physics and Society · Physics 2023-12-25 Alfredo Braunstein , Louise Budzynski , Matteo Mariani

As the COVID-19 pandemic continues to ravage the world, it is of critical significance to provide a timely risk prediction of the COVID-19 in multi-level. To implement it and evaluate the public health policies, we develop a framework with…

Physics and Society · Physics 2020-12-02 Lingxiao Wang , Tian Xu , Till Hannes Stoecker , Horst Stoecker , Yin Jiang , Kai Zhou

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

Populations and Evolution · Quantitative Biology 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

The dramatic outbreak of the coronavirus disease 2019 (COVID-19) pandemics and its ongoing progression boosted the scientific community's interest in epidemic modeling and forecasting. The SIR (Susceptible-Infected-Removed) model is a…

Populations and Evolution · Quantitative Biology 2021-02-24 Dimiter Prodanov

This paper proposes a data-driven approximate Bayesian computation framework for parameter estimation and uncertainty quantification of epidemic models, which incorporates two novelties: (i) the identification of the initial conditions by…

Applications · Statistics 2023-06-28 Americo Cunha , David A. W. Barton , Thiago G. Ritto

This paper seeks to study the evolution of the COVID-19 pandemic based on daily published data from Worldometer website, using a time-dependent SIR model. Our findings indicate that this model fits well such data, for different chosen…

Populations and Evolution · Quantitative Biology 2023-11-28 Rawan H. Madi , Sophie M. Moufawad , Nabil R. Nassif