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As the COVID-19 pandemic evolves, reliable prediction plays an important role for policy making. The classical infectious disease model SEIR (susceptible-exposed-infectious-recovered) is a compact yet simplistic temporal model. The…

Machine Learning · Computer Science 2020-10-20 Yunling Zheng , Zhijian Li , Jack Xin , Guofa Zhou

Disease spread in most biological populations requires the proximity of agents. In populations where the individuals have spatial mobility, the contact graph is generated by the "collision dynamics" of the agents, and thus the evolution of…

Physics and Society · Physics 2007-06-07 Z. Toroczkai , H. Guclu

We introduce a mathematical description of the impact of sociality in the spread of infectious diseases by integrating an epidemiological dynamics with a kinetic modeling of population-based contacts. The kinetic description leads to study…

Physics and Society · Physics 2021-04-02 G. Dimarco , B. Perthame , G. Toscani , M. Zanella

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

Advancing epidemic dynamics forecasting is vital for targeted interventions and safeguarding public health. Current approaches mainly fall into two categories: mechanism-based and data-driven models. Mechanism-based models are constrained…

Machine Learning · Computer Science 2025-08-05 Rui Sun , Chenghua Gong , Tianjun Gu , Yuhao Zheng , Jie Ding , Juyuan Zhang , Liming Pan , Linyuan Lü

We have developed a globally applicable diagnostic Covid-19 model by augmenting the classical SIR epidemiological model with a neural network module. Our model does not rely upon previous epidemics like SARS/MERS and all parameters are…

Physics and Society · Physics 2020-11-24 Raj Dandekar , Chris Rackauckas , George Barbastathis

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

Deterministic approximations to stochastic Susceptible-Infectious-Susceptible models typically predict a stable endemic steady-state when above threshold. This can be hard to relate to the underlying stochastic dynamics, which has no…

Populations and Evolution · Quantitative Biology 2022-08-12 Christopher E. Overton , Robert R. Wilkinson , Adedapo Loyinmi , Joel C. Miller , Kieran J. Sharkey

We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model. Through the use of a normal form coordinate transform, we are able to analytically derive the stochastic center manifold along with the…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 Eric Forgoston , Lora Billings , Ira B. Schwartz

We introduce a Bayesian sequential data assimilation method for COVID-19 forecasting. It is assumed that suitable transmission, epidemic and observation models are available and previously validated and the transmission and epidemic models…

Mathematical models of infectious diseases exhibit robust dynamics such as stable endemic or a disease-free equilibrium, or convergence of the solutions to periodic epidemic waves. The present work shows that the accuracy of such dynamics…

Applications · Statistics 2022-05-04 Hadeel AlQadi , Majid Bani-Yaghoub

The COVID-19 pandemic has been characterised by multiple waves of transmission driven by interventions and emerging variants, challenging epidemic models that assume gradually evolving transmission dynamics. We propose a class of…

Applications · Statistics 2026-05-05 Patrick Aschermayr , Konstantinos Kalogeropoulos , Nikolaos Demiris

The coronavirus disease 2019 (COVID-19) pandemic has quickly become a global public health crisis unseen in recent years. It is known that the structure of the human contact network plays an important role in the spread of transmissible…

Social and Information Networks · Computer Science 2020-10-08 Abby Leung , Xiaoye Ding , Shenyang Huang , Reihaneh Rabbany

In this paper, we study the spread of a classical SIR process on a two-layer random network, where the first layer represents the households, while the second layer models the contacts outside the households by a random scale-free graph. We…

Populations and Evolution · Quantitative Biology 2024-03-01 Ágnes Backhausz , Edit Bognár , Villő Csiszár , Damján Tárkányi , András Zempléni

In this paper we study a discrete-time SIS (susceptible-infected-susceptible) model, where the infection and healing parameters and the underlying network may change over time. We provide conditions for the model to be well-defined and…

Systems and Control · Electrical Eng. & Systems 2020-10-23 Philip E Pare , Sebin Gracy , Henrik Sandberg , Karl Henrik Johansson

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

Accurate epidemic forecasting is crucial for effective disease control and prevention. Traditional compartmental models often struggle to estimate temporally and spatially varying epidemiological parameters, while deep learning models…

Machine Learning · Computer Science 2025-04-08 Shuai Han , Lukas Stelz , Thomas R. Sokolowski , Kai Zhou , Horst Stöcker

Infectious diseases that incorporate pre-symptomatic transmission are challenging to monitor, model, predict and contain. We address this scenario by studying a variant of a stochastic susceptible-exposed-infected-recovered model on…

Physics and Society · Physics 2021-05-07 Bo Li , David Saad

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Optimization and Control · Mathematics 2020-12-22 Hailiang Liu , Xuping Tian

Mathematical models of SARS-CoV-2 spread are used for guiding the design of mitigation steps aimed at containing and decelerating the contagion, and at identifying impending breaches of health care system surge capacity. The challenges of…

Populations and Evolution · Quantitative Biology 2020-06-17 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo