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Micro-Action Recognition (MAR) aims to classify subtle human actions in video. However, annotating MAR datasets is particularly challenging due to the subtlety of actions. To this end, we introduce the setting of Semi-Supervised MAR…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Yan Zhang , Lechao Cheng , Yaxiong Wang , Zhun Zhong , Meng Wang

Single-Cell RNA sequencing (scRNA-seq) measurements have facilitated genome-scale transcriptomic profiling of individual cells, with the hope of deconvolving cellular dynamic changes in corresponding cell sub-populations to better…

Genomics · Quantitative Biology 2021-04-06 Seyednami Niyakan , Ehsan Hajiramezanali , Shahin Boluki , Siamak Zamani Dadaneh , Xiaoning Qian

Accurately segmenting and individualizing cells in SEM images is a highly promising technique for elucidating tissue architecture in oncology. While current AI-based methods are effective, errors persist, necessitating time-consuming manual…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Florian Robert , Alexia Calovoulos , Laurent Facq , Fanny Decoeur , Etienne Gontier , Christophe F. Grosset , Baudouin Denis de Senneville

Renal Cell Carcinoma is typically asymptomatic at the early stages for many patients. This leads to a late diagnosis of the tumor, where the curability likelihood is lower, and makes the mortality rate of Renal Cell Carcinoma high, with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Mohamad Mohamad , Francesco Ponzio , Santa Di Cataldo , Damien Ambrosetti , Xavier Descombes

Single-cell RNA sequencing (scRNA-seq) data exhibit strong and reproducible statistical structure. This has motivated the development of large-scale foundation models, such as TranscriptFormer, that use transformer-based architectures to…

Genomics · Quantitative Biology 2026-02-19 Huan Souza , Pankaj Mehta

Fined-grained anomalous cell detection from affected tissues is critical for clinical diagnosis and pathological research. Single-cell sequencing data provide unprecedented opportunities for this task. However, current anomaly detection…

Machine Learning · Computer Science 2024-05-01 Kaichen Xu , Yueyang Ding , Suyang Hou , Weiqiang Zhan , Nisang Chen , Jun Wang , Xiaobo Sun

Cell detection in pathological images presents unique challenges due to densely packed objects, subtle inter-class differences, and severe background clutter. In this paper, we propose CellMamba, a lightweight and accurate one-stage…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Ruochen Liu , Yi Tian , Jiahao Wang , Hongbin Liu , Xianxu Hou , Jingxin Liu

Cell tracking remains a pivotal yet challenging task in biomedical research. The full potential of deep learning for this purpose is often untapped due to the limited availability of comprehensive and varied training data sets. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Moritz Sturm , Lorenzo Cerrone , Fred A. Hamprecht

Obtaining a large amount of labeled data in medical imaging is laborious and time-consuming, especially for histopathology. However, it is much easier and cheaper to get unlabeled data from whole-slide images (WSIs). Semi-supervised…

Image and Video Processing · Electrical Eng. & Systems 2020-08-13 Zeyu Gao , Pargorn Puttapirat , Jiangbo Shi , Chen Li

Sequencing costs currently prohibit the application of single-cell mRNA-seq to many biological and clinical analyses. Targeted single-cell mRNA-sequencing reduces sequencing costs by profiling reduced gene sets that capture biological…

Genomics · Quantitative Biology 2022-02-15 Xiaoqiao Chen , Sisi Chen , Matt Thomson

In recent years, the field of single-cell data analysis has seen a marked advancement in the development of clustering methods. Despite advancements, most of these algorithms still concentrate on analyzing the provided single-cell matrix…

Machine Learning · Computer Science 2023-12-18 Dayu Hu , Ke Liang , Hao Yu , Xinwang Liu

We present scPilot, the first systematic framework to practice omics-native reasoning: a large language model (LLM) converses in natural language while directly inspecting single-cell RNA-seq data and on-demand bioinformatics tools. scPilot…

Artificial Intelligence · Computer Science 2026-02-13 Yiming Gao , Zhen Wang , Jefferson Chen , Mark Antkowiak , Mengzhou Hu , JungHo Kong , Dexter Pratt , Jieyuan Liu , Enze Ma , Zhiting Hu , Eric P. Xing

Prevalent supervised learning methods in natural language processing (NLP) are notoriously data-hungry, which demand large amounts of high-quality annotated data. In practice, acquiring such data is a costly endeavor. Recently, the superior…

Computation and Language · Computer Science 2023-11-01 Ruoyu Zhang , Yanzeng Li , Yongliang Ma , Ming Zhou , Lei Zou

While MLLMs have demonstrated adequate image understanding capabilities, they still struggle with pixel-level comprehension, limiting their practical applications. Current evaluation tasks like VQA and visual grounding remain too coarse to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Muzhi Zhu , Yuzhuo Tian , Hao Chen , Chunluan Zhou , Qingpei Guo , Yang Liu , Ming Yang , Chunhua Shen

Single-cell RNA sequencing (scRNA-seq) reveals cell heterogeneity, with cell clustering playing a key role in identifying cell types and marker genes. Recent advances, especially graph neural networks (GNNs)-based methods, have…

Genomics · Quantitative Biology 2025-10-03 Ping Xu , Zhiyuan Ning , Pengjiang Li , Wenhao Liu , Pengyang Wang , Jiaxu Cui , Yuanchun Zhou , Pengfei Wang

The Connectivity Map (CMap) is a large publicly available database of cellular transcriptomic responses to chemical and genetic perturbations built using a standardized acquisition protocol known as the L1000 technique. Databases such as…

Quantitative Methods · Quantitative Biology 2024-05-01 Steven Shave , Richard Kasprowicz , Abdullah M. Athar , Denise Vlachou , Neil O. Carragher , Cuong Q. Nguyen

Most cellular phenotypes are genetically complex. Identifying the set of genes that are most closely associated with a specific cellular state is still an open question in many cases. Here we study the transcriptional profile of cellular…

Quantitative Methods · Quantitative Biology 2024-06-21 Alda Sabalic , Victoria Moiseeva , Andres Cisneros , Oleg Deryagin , Eusebio Perdiguero , Pura Muñoz-Canoves , Jordi Garcia-Ojalvo

Digital Pathology is a cornerstone in the diagnosis and treatment of diseases. A key task in this field is the identification and segmentation of cells in hematoxylin and eosin-stained images. Existing methods for cell segmentation often…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Fabian Hörst , Moritz Rempe , Helmut Becker , Lukas Heine , Julius Keyl , Jens Kleesiek

Cell shape analysis is important in biomedical research. Deep learning methods may perform to segment individual cells if they use sufficient training data that the boundary of each cell is annotated. However, it is very time-consuming for…

Image and Video Processing · Electrical Eng. & Systems 2020-02-26 Kazuya Nishimura , Dai Fei Elmer Ker , Ryoma Bise

Column type annotation is the task of annotating the columns of a relational table with the semantic type of the values contained in each column. Column type annotation is an important pre-processing step for data search and data…

Computation and Language · Computer Science 2023-08-01 Keti Korini , Christian Bizer
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