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Understanding material failure is critical for designing stronger and lighter structures by identifying weaknesses that could be mitigated. Existing full-physics numerical simulation techniques involve trade-offs between speed, accuracy,…

Biomedical Foundation Models (FMs) are rapidly transforming AI-enabled healthcare research and entering clinical validation. However, their susceptibility to learning non-biological technical features -- including variations in…

Accurate lung tumor segmentation is crucial for improving diagnosis, treatment planning, and patient outcomes in oncology. However, the complexity of tumor morphology, size, and location poses significant challenges for automated…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Elena Mulero Ayllón , Massimiliano Mantegna , Linlin Shen , Paolo Soda , Valerio Guarrasi , Matteo Tortora

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation),…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Weiming Chen , Xitong Ling , Xidong Wang , Zhenyang Cai , Yijia Guo , Mingxi Fu , Ziyi Zeng , Minxi Ouyang , Jiawen Li , Yizhi Wang , Tian Guan , Benyou Wang , Yonghong He

Accurate multi-organ segmentation in abdominal CT scans is essential for computer-aided diagnosis and treatment. While convolutional neural networks (CNNs) have long been the standard approach in medical image segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Lukas Bayer , Sheethal Bhat , Andreas Maier

Foundation models have emerged as robust models with label efficiency in diverse domains. In medical imaging, these models contribute to the advancement of medical diagnoses due to the difficulty in obtaining labeled data. However, it is…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Dilermando Queiroz , Anderson Carlos , Maíra Fatoretto , Luis Filipe Nakayama , André Anjos , Lilian Berton

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Dequan Wang , Xiaosong Wang , Lilong Wang , Mengzhang Li , Qian Da , Xiaoqiang Liu , Xiangyu Gao , Jun Shen , Junjun He , Tian Shen , Qi Duan , Jie Zhao , Kang Li , Yu Qiao , Shaoting Zhang

Foundation models pretrained on large-scale histopathology data have found great success in various fields of computational pathology, but their impact on regressive biomarker prediction remains underexplored. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Alexander Blezinger , Wolfgang Nejdl , Ming Tang

Foundation models (FMs) promise to generalize medical imaging, but their effectiveness varies. It remains unclear how pre-training domain (medical vs. general), paradigm (e.g., text-guided), and architecture influence embedding quality,…

The recent popularity of foundation models and the pre-train-and-adapt paradigm, where a large-scale model is transferred to downstream tasks, is gaining attention for volumetric medical image segmentation. However, current transfer…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Julio Silva-Rodríguez , Jose Dolz , Ismail Ben Ayed

Chronic wounds such as diabetic foot ulcers and pressure injuries require accurate tissue-level assessment to guide treatment planning and monitor healing progression. While deep learning methods have advanced automated wound analysis, most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Muhammad Ashad Kabir , Rabin Dulal

Foundation models are reshaping computational histopathology, yet their value for whole-slide image retrieval relative to strong patch-based and supervised aggregation baselines remains unclear. We benchmarked ten pipelines on 9,387…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tianhao Lei , Parsa Esmaeilkhani , Saghir Alfasly , Wataru Uegami , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

Large pretrained transformers are increasingly being developed as generalised foundation models which can underpin powerful task-specific artificial intelligence models. Histopathology foundation models show great promise across many tasks,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-10 Jack Breen , Katie Allen , Kieran Zucker , Lucy Godson , Nicolas M. Orsi , Nishant Ravikumar

Deep learning models for medical image segmentation and object detection are becoming increasingly available as clinical products. However, as details are rarely provided about the training data, models may unexpectedly fail when cases…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Jack Highton , Quok Zong Chong , Samuel Finestone , Arian Beqiri , Julia A. Schnabel , Kanwal K. Bhatia

Patient education materials for solid-organ transplantation vary substantially across U.S. centers, yet no systematic method exists to quantify this heterogeneity at scale. We introduce a framework that grounds the same patient questions in…

Information Retrieval · Computer Science 2026-03-24 Yubo Li , Ramayya Krishnan , Rema Padman

Tuberculosis (TB) is a major global health challenge, and is compounded by co-morbidities such as HIV, diabetes, and anemia, which complicate treatment outcomes and contribute to heterogeneous patient responses. Traditional models of TB…

Machine Learning · Computer Science 2024-11-19 Ethan Wu , Caleb Ellington , Ben Lengerich , Eric P. Xing

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

Foundation models have emerged as a powerful tool for many AI problems. Despite the tremendous success of foundation models, effective adaptation to new tasks, particularly those with limited labels, remains an open question and lacks…

Machine Learning · Computer Science 2024-02-26 Zhuoyan Xu , Zhenmei Shi , Junyi Wei , Fangzhou Mu , Yin Li , Yingyu Liang

Whole slide image (WSI) analysis is gaining prominence within the medical imaging field. Recent advances in pathology foundation models have shown the potential to extract powerful feature representations from WSIs for downstream tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Yanyan Huang , Weiqin Zhao , Yihang Chen , Yu Fu , Lequan Yu

Foundation models, pre-trained on large image datasets and capable of capturing rich feature representations, have recently shown potential for zero-shot image registration. However, their performance has mostly been tested in the context…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Hanxue Gu , Yaqian Chen , Nicholas Konz , Qihang Li , Maciej A. Mazurowski