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Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka

Background and objective: Prior probability shift between training and deployment datasets challenges deep learning-based medical image classification. Standard correction methods reweight posterior probabilities to adjust prior bias, yet…

Quantitative Methods · Quantitative Biology 2025-11-06 Takaaki Tachibana , Toru Nagasaka , Yukari Adachi , Hiroki Kagiyama , Ryota Ito , Mitsugu Fujita , Kimihiro Yamashita , Yoshihiro Kakeji

Foundation models are widely employed in medical image analysis, due to their high adaptability and generalizability for downstream tasks. With the increasing number of foundation models being released, model selection has become an…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Fuping Wu , Bartlomiej W. Papiez

Despite their successes in vision and language, foundation models have stumbled in pathology, revealing low accuracy, instability, and heavy computational demands. These shortcomings stem not from tuning problems but from deeper conceptual…

Artificial Intelligence · Computer Science 2026-04-21 Hamid R. Tizhoosh

While deep learning has shown promise in the domain of disease classification from medical images, models based on state-of-the-art convolutional neural network architectures often exhibit performance loss due to dataset shift. Models…

Machine Learning · Computer Science 2020-01-14 Joseph D. Janizek , Gabriel Erion , Alex J. DeGrave , Su-In Lee

Universal lesion detection and tagging (ULDT) in CT studies is critical for tumor burden assessment and tracking the progression of lesion status (growth/shrinkage) over time. However, a lack of fully annotated data hinders the development…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Alexander Shieh , Tejas Sudharshan Mathai , Jianfei Liu , Angshuman Paul , Ronald M. Summers

Cell nuclei instance segmentation is a crucial task in digital kidney pathology. Traditional automatic segmentation methods often lack generalizability when applied to unseen datasets. Recently, the success of foundation models (FMs) has…

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Kang Yu , Dingyu Wang , Zimu Yuan , Nan Zhou , Jiajun Liu , Jiaxin Liu , Shanggui Liu , Yaoyan Zheng , Huishu Yuan , Di Huang , Dong Jiang

Developing robust and versatile deep-learning models is essential for enhancing diagnostic accuracy and guiding clinical interventions in medical imaging, but it requires a large amount of annotated data. The advancement of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Nahid Ul Islam , DongAo Ma , Jiaxuan Pang , Shivasakthi Senthil Velan , Michael Gotway , Jianming Liang

Recent advances in artificial intelligence have witnessed the emergence of large-scale deep learning models capable of interpreting and generating both textual and imaging data. Such models, typically referred to as foundation models, are…

Pathology foundation models (PFMs) achieve strong performance on diverse histopathology tasks, but their sensitivity to hospital-specific domain shifts remains underexplored. We systematically evaluate state-of-the-art PFMs on TCGA…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Mengliang Zhang

Accurate cell nuclei segmentation is critical for downstream tasks in kidney pathology and remains a major challenge due to the morphological diversity and imaging variability of renal tissues. While our prior work has evaluated…

Ensuring consistent performance across diverse populations and incorporating fairness into machine learning models are crucial for advancing medical image diagnostics and promoting equitable healthcare. However, many databases do not…

Computer Vision and Pattern Recognition · Computer Science 2025-02-24 Dilermando Queiroz , André Anjos , Lilian Berton

The objective of this study is to develop a robust deep learning-based framework to distinguish COVID-19, Community-Acquired Pneumonia (CAP), and Normal cases based on chest CT scans acquired in different imaging centers using various…

Chest computed tomography (CT) is central to the detection and management of thoracic disease, yet the growing scale and complexity of volumetric imaging increasingly exceed what can be addressed by scan-level prediction alone. Clinically…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xuguang Bai , Mingxuan Liu , Tongxi Song , Yifei Chen , Hongjia Yang , Kasidit Anmahapong , Zihan Li , Ying Zhou , Qiyuan Tian

The synergistic interpretation of anatomical information from computed tomography (CT) and metabolic information from positron emission tomography (PET) is important to oncologic imaging. However, existing deep learning methods for PET/CT…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Xiaofeng Liu , Qianru Zhang , Thibault Marin , Menghua Xia , Chi Liu , Georges El Fakhri , Jinsong Ouyang

Background: RETFound, a self-supervised, retina-specific foundation model (FM), showed potential in downstream applications. However, its comparative performance with traditional deep learning (DL) models remains incompletely understood.…

Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shiqi Huang , Yipei Wang , Natasha Thorley , Alexander Ng , Shaheer Saeed , Mark Emberton , Shonit Punwani , Veeru Kasivisvanathan , Dean Barratt , Daniel Alexander , Yipeng Hu

Recent advancements in AI and medical imaging offer transformative potential in emergency head CT interpretation for reducing assessment times and improving accuracy in the face of an increasing request of such scans and a global shortage…