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Large pre-trained Vision-Language Models (VLMs) such as Contrastive Language-Image Pre-training (CLIP) have been shown to be susceptible to adversarial attacks, raising concerns about their deployment in safety-critical applications like…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Lin Luo , Xin Wang , Bojia Zi , Shihao Zhao , Xingjun Ma , Yu-Gang Jiang

Autonomous driving (AD) has made significant strides in recent years. However, existing frameworks struggle to interpret and execute spontaneous user instructions, such as "overtake the car ahead." Large Language Models (LLMs) have…

Computation and Language · Computer Science 2024-04-05 Yunsheng Ma , Can Cui , Xu Cao , Wenqian Ye , Peiran Liu , Juanwu Lu , Amr Abdelraouf , Rohit Gupta , Kyungtae Han , Aniket Bera , James M. Rehg , Ziran Wang

Large-scale Protein Language Models (PLMs) have improved performance in protein prediction tasks, ranging from 3D structure prediction to various function predictions. In particular, AlphaFold, a ground-breaking AI system, could potentially…

Quantitative Methods · Quantitative Biology 2022-10-18 Mingyang Hu , Fajie Yuan , Kevin K. Yang , Fusong Ju , Jin Su , Hui Wang , Fei Yang , Qiuyang Ding

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2026-04-24 Yue Guo , Fanfu Wang , Jianwei Lv , Xincheng Shi , Yuchen Li , Youya Wang , Yunsheng Zeng , Yujing Liu , Yunhao Qiao , Gen Li , Junfeng Wang , Bo Yuan

Large language models (LLMs) have emerged as powerful tools in natural language processing (NLP), showing a promising future of artificial generated intelligence (AGI). Despite their notable performance in the general domain, LLMs have…

Computation and Language · Computer Science 2025-01-23 Jingyuan Chen , Tao Wu , Wei Ji , Fei Wu

In the past decades, recommender systems have attracted much attention in both research and industry communities, and a large number of studies have been devoted to developing effective recommendation models. Basically speaking, these…

Information Retrieval · Computer Science 2023-05-12 Junjie Zhang , Ruobing Xie , Yupeng Hou , Wayne Xin Zhao , Leyu Lin , Ji-Rong Wen

Metaphor detection (MD) suffers from limited training data. In this paper, we started with a linguistic rule called Metaphor Identification Procedure and then proposed a novel multi-task learning framework to transfer knowledge in basic…

Computation and Language · Computer Science 2023-05-29 Shenglong Zhang , Ying Liu

With the rapid development of large language models (LLMs) and their integration into large multimodal models (LMMs), there has been impressive progress in zero-shot completion of user-oriented vision-language tasks. However, a gap remains…

Computation and Language · Computer Science 2024-04-16 Fuxiao Liu , Xiaoyang Wang , Wenlin Yao , Jianshu Chen , Kaiqiang Song , Sangwoo Cho , Yaser Yacoob , Dong Yu

Accurate diagnosis of skin diseases remains a significant challenge due to the complex and diverse visual features present in dermatoscopic images, often compounded by a lack of interpretability in existing purely visual diagnostic models.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Kexin Yu , Zihan Xu , Jialei Xie , Carter Adams

Developing a high-performing large language models (LLMs) for low-resource languages such as Urdu, present several challenges. These challenges include the scarcity of high-quality datasets, multilingual inconsistencies, and safety…

Computation and Language · Computer Science 2025-10-13 Muhammad Ali Shafique , Kanwal Mehreen , Muhammad Arham , Maaz Amjad , Sabur Butt , Hamza Farooq

Fine-tuning Large Language Models (LLMs) incurs considerable training costs, driving the need for data-efficient training with optimised data ordering. Human-inspired strategies offer a solution by organising data based on human learning…

Computation and Language · Computer Science 2024-11-06 Yushi Yang , Andrew M. Bean , Robert McCraith , Adam Mahdi

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

Large language models (LLMs) are rapidly transforming knowledge work by improving the quality and efficiency of tasks such as writing, coding, and data analysis. However, their growing use in education has exposed a learning-performance…

The performance of large language models (LLMs) depends on how they are prompted, with choices spanning both the high-level prompting pattern (e.g., Zero-Shot, CoT, ReAct, ReWOO) and the specific prompt content (instructions and few-shot…

Machine Learning · Computer Science 2025-11-05 Claudio Spiess , Mandana Vaziri , Louis Mandel , Martin Hirzel

Pathology foundation models (PFMs) have demonstrated strong representational capabilities through self-supervised pre-training on large-scale, unannotated histopathology image datasets. However, their diverse yet opaque pretraining…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yuxiang Xiao , Yang Hu , Bin Li , Tianyang Zhang , Zexi Li , Huazhu Fu , Jens Rittscher , Kaixiang Yang

The ability of large language models (LLMs) to follow instructions is crucial to real-world applications. Despite recent advances, several studies have highlighted that LLMs struggle when faced with challenging instructions, especially…

Computation and Language · Computer Science 2024-04-04 Haoran Sun , Lixin Liu , Junjie Li , Fengyu Wang , Baohua Dong , Ran Lin , Ruohui Huang

Large language models are increasingly used within larger systems ("LLM agents"). These make a sequence of LLM calls, each call providing the LLM with a combination of instructions, observations, and interaction history. The design of the…

Artificial Intelligence · Computer Science 2026-05-05 Noga Peleg Pelc , Gal A. Kaminka , Yoav Goldberg

Amino acid sequence portrays most intrinsic form of a protein and expresses primary structure of protein. The order of amino acids in a sequence enables a protein to acquire a particular stable conformation that is responsible for the…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , David Fernandez-Baca , Akshay Deepak , Sudhakar Tripathi

With the rapid advancement of Large Language Models (LLMs), the demand for robust instruction-following capabilities in code generation tasks has grown significantly. Code generation not only facilitates faster prototyping and automated…

Software Engineering · Computer Science 2025-08-05 Kaiwen Yan , Hongcheng Guo , Xuanqing Shi , Shaosheng Cao , Donglin Di , Zhoujun Li

The safety of Large Language Models (LLMs) is crucial for the development of trustworthy AI applications. Existing red teaming methods often rely on seed instructions, which limits the semantic diversity of the synthesized adversarial…

Computation and Language · Computer Science 2025-10-10 Muxi Diao , Yutao Mou , Keqing He , Hanbo Song , Lulu Zhao , Shikun Zhang , Wei Ye , Kongming Liang , Zhanyu Ma