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Objective: Quantitative technique based on In-line phase-contrast computed tomography with single scanning attracts more attention in application due to the flexibility of the implementation. However, the quantitative results usually suffer…

Medical Physics · Physics 2022-06-13 Suyu Liao , Shiwo Deng , Yining Zhu , Huitao Zhang , Peiping Zhu , Kai Zhang , Xing Zhao

Clinical measurement of a patient's axial eye length is emerging as a crucial approach to track progression and monitor management of myopia. However, the preferred method for such measurements is swept-source OCT, whose cost prohibits…

Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue, but lacks functional information. We present dynamic full-field optical coherence tomography to image living human induced…

SPECT provides a mechanism to perform absorbed-dose quantification tasks for $\alpha$-particle radiopharmaceutical therapies ($\alpha$-RPTs). However, quantitative SPECT for $\alpha$-RPT is challenging due to the low number of detected…

We present a novel approach allowing an optically pumped magnetometer (OPM) to be operated within Earth's magnetic field as a vector magnetometer whose sensitive axis can be freely defined. This approach enables the measurement of any…

Instrumentation and Detectors · Physics 2024-08-20 Thomas Schönau , Theo Scholtes , Florian Wittkämper , Alexander Sekels , Stefan Hiebel , Gregor Oelsner , Ronny Stolz

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

A non-invasive functional-brain-imaging system based on optically-pumped-magnetometers (OPM) is presented. The OPM-based magnetoencephalography (MEG) system features 20 OPM channels conforming to the subject's scalp. Due to proximity (12…

Dynamic full-field optical coherence microscopy (d-FF-OCM) is a label-free imaging technique that captures intrinsic subcellular motions to generate functional contrast. This dynamic approach yields images with fluorescence-like contrast,…

Optics · Physics 2025-08-06 Erikas Tarvydas , Austeja Treciokaite , Egidijus Auksorius

Positive operator valued measurements (POVMs) play an important role in efficient quantum communication and computation. While optical systems are one of the strongest candidates for long distance quantum communication and information…

Quantum Physics · Physics 2022-01-19 Jaskaran Singh , Arvind , Sandeep K. Goyal

We demonstrate volumetric fluorescence lifetime microscopy (FLIM) using the electro-optic FLIM technique. Images acquired in a selective plane illumination microscope are gated using a Pockels cell driven at 80 MHz, enabling light sheet…

Optical approaches have made great strides towards the goal of high-speed, energy-efficient computing necessary for modern deep learning and AI applications. Read-in and read-out of data, however, limit the overall performance of existing…

Emerging Technologies · Computer Science 2024-02-06 Alexander Song , Sai Nikhilesh Murty Kottapalli , Rahul Goyal , Bernhard Schölkopf , Peer Fischer

Deep neural networks (DNNs) enhance the accuracy and efficiency of reconstructing key parameters from time-resolved photon arrival signals recorded by single-photon detectors. However, the performance of conventional backpropagation-based…

Machine Learning · Computer Science 2025-04-15 Zhenya Zang , Xingda Li , David Day Uei Li

Generalized quantum measurements, described by positive operator-valued measures (POVMs), are essential for modeling realistic processes in open quantum systems. While quantum process tomography can fully characterize a POVM, it is…

Quantum Physics · Physics 2025-10-10 Sahil , Sohail

Understanding the nanoscale carrier dynamics induced by light excitation is the key to unlocking futuristic devices and innovative functionalities in advanced materials. Optical pump-probe scanning tunneling microscopy (OPP-STM) has opened…

Materials Science · Physics 2024-03-28 Katsuya Iwaya , Hiroyuki Mogi , Shoji Yoshida , Yusuke Arashida , Osamu Takeuchi , Hidemi Shigekawa

Score-based diffusion models have shown significant promise in the field of sparse-view CT reconstruction. However, the projection dataset is large and riddled with redundancy. Consequently, applying the diffusion model to unprocessed data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-16 Pengfei Yu , Bin Huang , Minghui Zhang , Weiwen Wu , Shaoyu Wang , Qiegen Liu

Ultrafast 3D imaging is indispensable for visualizing complex and dynamic biological processes. Conventional scanning-based techniques necessitate an inherent trade-off between acquisition speed and space-bandwidth product (SBP). Emerging…

Optical coherence tomography (OCT) image analysis plays an important role in the field of ophthalmology. Current successful analysis models rely on available large datasets, which can be challenging to be obtained for certain tasks. The use…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Kun Huang , Xiao Ma , Yuhan Zhang , Na Su , Songtao Yuan , Yong Liu , Qiang Chen , Huazhu Fu

Exposure to laser light alters cell culture examination via optical microscopic imaging techniques, also based on label-free coherent digital holography. To mitigate this detrimental feature, researchers tend to use a broader spectrum and…

Photoacoustic microscopy is becoming an important tool for the biomedical research. It has been widely used in biological researches, such as structural imaging of vasculature, brain structural and functional imaging, and tumor detection.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Xianlin Song , Jianshuang Wei , Lingfang Song

Measurement of the optical transmission matrix (TM) of an opaque material is an advanced form of space-variant aberration correction. Beyond imaging, TM-based methods are emerging in a range of fields including optical communications,…