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Spatial-temporal forecasting and imputation are important for real-world intelligent systems. Most existing methods are tailored for individual forecasting or imputation tasks but are not designed for both. Additionally, they are less…

Machine Learning · Computer Science 2025-05-21 YiHeng Huang , Xiaowei Mao , Shengnan Guo , Yubin Chen , Junfeng Shen , Tiankuo Li , Youfang Lin , Huaiyu Wan

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

Sequential processes in real-world often carry a combination of simple subsystems that interact with each other in certain forms. Learning such a modular structure can often improve the robustness against environmental changes. In this…

Machine Learning · Computer Science 2023-11-07 Ziyu Wang , Wenhao Jiang , Zixuan Zhang , Wei Tang , Junchi Yan

Biomolecular Neural Networks (BNNs), artificial neural networks with biologically synthesizable architectures, achieve universal function approximation capabilities beyond simple biological circuits. However, training BNNs remains…

Machine Learning · Computer Science 2025-09-09 Eric Palanques-Tost , Hanna Krasowski , Murat Arcak , Ron Weiss , Calin Belta

Single-cell RNA sequencing (scRNA-seq) provides high-dimensional profiles of cellular states, enabling data-driven modeling of cellular dynamics over time. In practice, time-resolved scRNA-seq is collected at only a few discrete time points…

Machine Learning · Computer Science 2026-05-22 Siyu Pu , Qingqing Long , Xiaohan Huang , Haotian Chen , Jiajia Wang , Meng Xiao , Xiao Luo , Hengshu Zhu , Yuanchun Zhou , Xuezhi Wang

The integration of spatial multi-omics data from single tissues is crucial for advancing biological research. However, a significant data imbalance impedes progress: while spatial transcriptomics data is relatively abundant, spatial…

Artificial Intelligence · Computer Science 2026-02-06 Zhaorui Jiang , Yingfang Yuan , Lei Hu , Wei Pang

Self-training via pseudo labeling is a conventional, simple, and popular pipeline to leverage unlabeled data. In this work, we first construct a strong baseline of self-training (namely ST) for semi-supervised semantic segmentation via…

Computer Vision and Pattern Recognition · Computer Science 2022-03-04 Lihe Yang , Wei Zhuo , Lei Qi , Yinghuan Shi , Yang Gao

With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…

Genomics · Quantitative Biology 2024-08-14 Donghai Fang , Fangfang Zhu , Dongting Xie , Wenwen Min

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

Real-time monocular 3D reconstruction is a challenging problem that remains unsolved. Although recent end-to-end methods have demonstrated promising results, tiny structures and geometric boundaries are hardly captured due to their…

Computer Vision and Pattern Recognition · Computer Science 2023-07-26 Chenyangguang Zhang , Zhiqiang Lou , Yan Di , Federico Tombari , Xiangyang Ji

This review maps developments in stochastic modeling, highlighting non-standard approaches and their applications to biology and epidemiology. It brings together four strands: (1) core models for systems that evolve with randomness; (2)…

Dynamical Systems · Mathematics 2025-10-24 Yassine Sabbar , Kottakkaran Sooppy Nisar

Sequential Resource Allocation with situational constraints presents a significant challenge in real-world applications, where resource demands and priorities are context-dependent. This paper introduces a novel framework, SCRL, to address…

Artificial Intelligence · Computer Science 2025-06-18 Libo Zhang , Yang Chen , Toru Takisaka , Kaiqi Zhao , Weidong Li , Jiamou Liu

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

Genomics · Quantitative Biology 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian

Spatial Transcriptomics is a groundbreaking technology that integrates histology images with spatially resolved gene expression profiles. Among the various Spatial Transcriptomics techniques available, Visium has emerged as the most widely…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Daniela Ruiz , Paula Cárdenas , Leonardo Manrique , Daniela Vega , Gabriel M. Mejia , Pablo Arbeláez

Single-cell RNA sequencing (scRNA-seq) is a fast growing approach to measure the genome-wide transcriptome of many individual cells in parallel, but results in noisy data with many dropout events. Existing methods to learn molecular…

Quantitative Methods · Quantitative Biology 2018-02-27 Beyrem Khalfaoui , Jean-Philippe Vert

Recent advancements in spatial transcriptomics technologies allow researchers to simultaneously measure RNA expression levels for hundreds to thousands of genes while preserving spatial information within tissues, providing critical…

Methodology · Statistics 2025-07-31 Catherine Higgins , Jingyi Jessica Li , Michelle Carey

Single-shot magnetic resonance (MR) imaging acquires the entire k-space data in a single shot and it has various applications in whole-body imaging. However, the long acquisition time for the entire k-space in single-shot fast spin echo…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Hemant Kumar Aggarwal , Sudhanya Chatterjee , Dattesh Shanbhag , Uday Patil , K. V. S. Hari

The rapid development of spatial transcriptomics(ST) enables the measurement of gene expression at spatial resolution, making it possible to simultaneously profile the gene expression, spatial locations of spots, and the matched…

Artificial Intelligence · Computer Science 2024-06-19 Changxi Chi , Hang Shi , Qi Zhu , Daoqiang Zhang , Wei Shao

Recent advancements in Spatial Transcriptomics (ST) technology have facilitated detailed gene expression analysis within tissue contexts. However, the high costs and methodological limitations of ST necessitate a more robust predictive…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Youngmin Chung , Ji Hun Ha , Kyeong Chan Im , Joo Sang Lee

This paper considers a class of reinforcement learning problems, which involve systems with two types of states: stochastic and pseudo-stochastic. In such systems, stochastic states follow a stochastic transition kernel while the…

Machine Learning · Computer Science 2023-11-09 Honghao Wei , Xin Liu , Weina Wang , Lei Ying