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Spatio-temporal predictive learning is a learning paradigm that enables models to learn spatial and temporal patterns by predicting future frames from given past frames in an unsupervised manner. Despite remarkable progress in recent years,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Cheng Tan , Siyuan Li , Zhangyang Gao , Wenfei Guan , Zedong Wang , Zicheng Liu , Lirong Wu , Stan Z. Li

Robustness and generalizability in medical image segmentation are often hindered by scarcity and limited diversity of training data, which stands in contrast to the variability encountered during inference. While conventional strategies --…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang

Spatially resolved transcriptomics brings exciting breakthroughs to single-cell analysis by providing physical locations along with gene expression. However, as a cost of the extremely high spatial resolution, the cellular level spatial…

Genomics · Quantitative Biology 2024-02-19 Hongzhi Wen , Wenzhuo Tang , Wei Jin , Jiayuan Ding , Renming Liu , Xinnan Dai , Feng Shi , Lulu Shang , Hui Liu , Yuying Xie

Single-cell RNA sequencing (scRNA-seq) enables transcriptomic profiling at cellular resolution but suffers from pervasive dropout events that obscure biological signals. We present SCR-MF, a modular two-stage workflow that combines…

Machine Learning · Computer Science 2025-11-24 Ali Anaissi , Deshao Liu , Yuanzhe Jia , Weidong Huang , Widad Alyassine , Junaid Akram

Spatially resolved transcriptomics (ST) measures gene expression along with the spatial coordinates of the measurements. The analysis of ST data involves significant computation complexity. In this work, we propose gene expression…

Genomics · Quantitative Biology 2022-05-24 Zhuoyan Xu , Kris Sankaran

Cells in multicellular organisms coordinate to form structural and functional niches. With spatial transcriptomics (ST) enabling gene expression profiling in spatial contexts, it has been revealed that spatial niches serve as cohesive and…

Quantitative Methods · Quantitative Biology 2026-05-26 Mo Chen , Minsheng Hao , Xinquan Liu , Lin Deng , Peng Liu , Chen Li , Dongfang Wang , Kui Hua , Liang Guo , Xuegong Zhang , Lei Wei

Tabling is an evaluation strategy for Prolog programs that works by storing answers in a table space and then by using them in similar subgoals. Some tabling engines use call by subsumption, where it is determined that a subgoal will…

Programming Languages · Computer Science 2011-12-19 Flavio Cruz , Ricardo Rocha

While spatial transcriptomics (ST) has advanced our understanding of gene expression in tissue context, its high experimental cost limits its large-scale application. Predicting ST from pathology images is a promising, cost-effective…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Zhiceng Shi , Changmiao Wang , Jun Wan , Wenwen Min

The rapid advancement of spatial transcriptomics (ST), i.e., spatial gene expressions, has made it possible to measure gene expression within original tissue, enabling us to discover molecular mechanisms. However, current ST platforms…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xiaofei Wang , Stephen Price , Chao Li

Spiking Neural Networks (SNNs) demonstrate significant potential for energy-efficient neuromorphic computing through an event-driven paradigm. While training methods and computational models have greatly advanced, SNNs struggle to achieve…

Neural and Evolutionary Computing · Computer Science 2025-10-27 Jieyuan Zhang , Xiaolong Zhou , Shuai Wang , Wenjie Wei , Hanwen Liu , Qian Sun , Malu Zhang , Yang Yang , Haizhou Li

Spatially resolved transcriptomics represents a significant advancement in single-cell analysis by offering both gene expression data and their corresponding physical locations. However, this high degree of spatial resolution entails a…

Genomics · Quantitative Biology 2024-03-19 Xiaoyu Li , Wenwen Min , Shunfang Wang , Changmiao Wang , Taosheng Xu

Single-cell multi-omics (scMulti-omics) refers to the paired multimodal data, such as Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq), where the regulation of each cell was measured from different modalities, i.e.…

Machine Learning · Computer Science 2024-10-18 Dian Meng , Bohao Xing , Xinlei Huang , Yanran Liu , Yijun Zhou , Yongjun xiao , Zitong Yu , Xubin Zheng

For reinforcement learning in data-scarce domains like real-world robotics, intensive data reuse enhances efficiency but induces overfitting. While prior works focus on critic bias, representation-level instability in Self-Predictive…

Machine Learning · Computer Science 2026-05-15 Sanghyeob Song , Donghyeok Lee , Jinsik Kim , Sungroh Yoon

Sampling-based motion planning has emerged as a powerful approach for robotics, enabling exploration of complex, high-dimensional configuration spaces. When combined with Signal Temporal Logic (STL), a temporal logic widely used for…

Robotics · Computer Science 2026-02-20 Ahmad Ahmad , Shuo Liu , Roberto Tron , Calin Belta

Accurate and reliable lane detection is vital for the safe performance of lane-keeping assistance and lane departure warning systems. However, under certain challenging circumstances, it is difficult to get satisfactory performance in…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Yongqi Dong , Sandeep Patil , Bart van Arem , Haneen Farah

Pathology foundation models learn morphological representations through self-supervised pretraining on large-scale whole-slide images, yet they do not explicitly capture the underlying molecular state of the tissue. Spatial transcriptomics…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Minsoo Lee , Jonghyun Kim , Juseung Yun , Sunwoo Yu , Jongseong Jang

Hyperspectral image (HSI) classification presents inherent challenges due to high spectral dimensionality, significant domain shifts, and limited availability of labeled data. To address these issues, we propose a novel Active Transfer…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Muhammad Ahmad , Francesco Mauro , Manuel Mazzara , Salvatore Distefano , Adil Mehmood Khan , Silvia Liberata Ullo

The rise of single-cell sequencing technologies has revolutionized the exploration of drug resistance, revealing the crucial role of cellular heterogeneity in advancing precision medicine. By building computational models from existing…

Genomics · Quantitative Biology 2025-02-05 Yu-An Huang , Xiyue Cao , Zhu-Hong You , Yue-Chao Li , Xuequn Shang , Zhi-An Huang

While Hybrid Supervised Fine-Tuning (SFT) followed by Reinforcement Learning (RL) has become the standard paradigm for training LLM agents, effective mechanisms for data allocation between these stages remain largely underexplored. Current…

Artificial Intelligence · Computer Science 2026-04-14 Yang Zhao , Yangou Ouyang , Xiao Ding , Hepeng Wang , Bibo Cai , Kai Xiong , Jinglong Gao , Zhouhao Sun , Li Du , Bing Qin , Ting Liu

Semantic Change Detection (SCD) refers to the task of simultaneously extracting the changed areas and the semantic categories (before and after the changes) in Remote Sensing Images (RSIs). This is more meaningful than Binary Change…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Lei Ding , Jing Zhang , Kai Zhang , Haitao Guo , Bing Liu , Lorenzo Bruzzone
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