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Single-cell RNA sequencing (scRNA-seq) and spatially-resolved imaging/sequencing technologies have revolutionized biomedical research. On one hand, scRNA-seq provides information about a large portion of the transcriptome for individual…

Computational Engineering, Finance, and Science · Computer Science 2026-03-24 Arezou Rahimi , Luis A. Vale-Silva , Maria Faelth Savitski , Jovan Tanevski , Julio Saez-Rodriguez

Scene Coordinate Regression (SCR) is a visual localization technique that utilizes deep neural networks (DNN) to directly regress 2D-3D correspondences for camera pose estimation. However, current SCR methods often face challenges in…

Robotics · Computer Science 2025-08-26 Kuan Xu , Zeyu Jiang , Haozhi Cao , Shenghai Yuan , Chen Wang , Lihua Xie

Intelligent medical diagnosis has shown remarkable progress based on the large-scale datasets with precise annotations. However, fewer labeled images are available due to significantly expensive cost for annotating data by experts. To fully…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Wentao Lei , Lei Liu , Li Liu

Spatial Transformer Networks (STN) can generate geometric transformations which modify input images to improve the classifier's performance. In this work, we combine the idea of STN with Reinforcement Learning (RL). To this end, we break…

Machine Learning · Computer Science 2021-06-29 Fatemeh Azimi , Federico Raue , Joern Hees , Andreas Dengel

Spiking Neural Networks (SNNs), as one of the algorithmic models in neuromorphic computing, have gained a great deal of research attention owing to temporal information processing capability, low power consumption, and high biological…

Neural and Evolutionary Computing · Computer Science 2023-06-07 Chengting Yu , Zheming Gu , Da Li , Gaoang Wang , Aili Wang , Erping Li

Synthesizing realistic medical images provides a feasible solution to the shortage of training data in deep learning based medical image recognition systems. However, the quality control of synthetic images for data augmentation purposes is…

Computer Vision and Pattern Recognition · Computer Science 2020-08-27 Jiarong Ye , Yuan Xue , L. Rodney Long , Sameer Antani , Zhiyun Xue , Keith Cheng , Xiaolei Huang

Accurate and scalable cell type annotation remains a challenge in single-cell transcriptomics, especially when datasets exhibit strong batch effects or contain previously unseen cell populations. Here we introduce SpikGPT, a hybrid deep…

Quantitative Methods · Quantitative Biology 2025-12-04 Min Huang , Rishikesan Kamaleswaran

Speech-to-text translation (ST), which translates source language speech into target language text, has attracted intensive attention in recent years. Compared to the traditional pipeline system, the end-to-end ST model has potential…

Computation and Language · Computer Science 2019-12-17 Yuchen Liu , Jiajun Zhang , Hao Xiong , Long Zhou , Zhongjun He , Hua Wu , Haifeng Wang , Chengqing Zong

We study image segmentation in the biological domain, particularly trait segmentation from specimen images (e.g., butterfly wing stripes, beetle elytra). This fine-grained task is crucial for understanding the biology of organisms, but it…

Spatial-temporal (ST) graph modeling, such as traffic speed forecasting and taxi demand prediction, is an important task in deep learning area. However, for the nodes in graph, their ST patterns can vary greatly in difficulties for…

Machine Learning · Computer Science 2022-11-29 Hongjun Wang , Jiyuan Chen , Tong Pan , Zipei Fan , Boyuan Zhang , Renhe Jiang , Lingyu Zhang , Yi Xie , Zhongyi Wang , Xuan Song

Pathology image are essential for accurately interpreting lesion cells in cytopathology screening, but acquiring high-resolution digital slides requires specialized equipment and long scanning times. Though super-resolution (SR) techniques…

Computer Vision and Pattern Recognition · Computer Science 2024-06-27 Wenting Chen , Jie Liu , Tommy W. S. Chow , Yixuan Yuan

Capturing the structure of a data-generating process by means of appropriate inductive biases can help in learning models that generalize well and are robust to changes in the input distribution. While methods that harness spatial and…

Spatial Transcriptomics (ST) provides spatially-resolved gene expression, offering crucial insights into tissue architecture and complex diseases. However, its prohibitive cost limits widespread adoption, leading to significant attention on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Taejin Jeong , Joohyeok Kim , Jinyeong Kim , Chanyoung Kim , Seong Jae Hwang

Sleep staging is critical to assess sleep quality and diagnose disorders. Despite advancements in artificial intelligence enabling automated sleep staging, significant challenges remain: (1) Simultaneously extracting prominent temporal and…

Neurons and Cognition · Quantitative Biology 2025-09-26 Jingying Ma , Qika Lin , Ziyu Jia , Mengling Feng

Whole slide images (WSIs) enable weakly supervised prognostic modeling via multiple instance learning (MIL). Spatial transcriptomics (ST) preserves in situ gene expression, providing a spatial molecular context that complements morphology.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Lihe Liu , Xiaoxi Pan , Yinyin Yuan , Lulu Shang

Spatial transcriptomics provides a molecularly rich description of tissue organization, enabling unsupervised discovery of tissue niches -- spatially coherent regions of distinct cell-type composition and function that are relevant to both…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Arbel Hizmi , Artemii Bakulin , Shai Bagon , Nir Yosef

Spiking neural networks (SNNs) have demonstrated excellent capabilities in various intelligent scenarios. Most existing methods for training SNNs are based on the concept of synaptic plasticity; however, learning in the realistic brain also…

Neural and Evolutionary Computing · Computer Science 2023-04-04 Hongze Sun , Wuque Cai , Baoxin Yang , Yan Cui , Yang Xia , Dezhong Yao , Daqing Guo

We propose a compositional approach to synthesize policies for networks of continuous-space stochastic control systems with unknown dynamics using model-free reinforcement learning (RL). The approach is based on implicitly abstracting each…

Systems and Control · Electrical Eng. & Systems 2022-08-09 Abolfazl Lavaei , Mateo Perez , Milad Kazemi , Fabio Somenzi , Sadegh Soudjani , Ashutosh Trivedi , Majid Zamani

Unsupervised Change Detection (UCD) in multimodal Remote Sensing (RS) images remains a difficult challenge due to the inherent spatio-temporal complexity within data, and the heterogeneity arising from different imaging sensors. Inspired by…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Lei Ding , Xibing Zuo , Danfeng Hong , Haitao Guo , Jun Lu , Zhihui Gong , Lorenzo Bruzzone

Hyperspectral image super-resolution has attained widespread prominence to enhance the spatial resolution of hyperspectral images. However, convolution-based methods have encountered challenges in harnessing the global spatial-spectral…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Shi Chen , Lefei Zhang , Liangpei Zhang
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