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Large language models (LLMs) have enabled the creation of multi-modal LLMs that exhibit strong comprehension of visual data such as images and videos. However, these models usually rely on extensive visual tokens from visual encoders,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Yiwu Zhong , Zhuoming Liu , Yin Li , Liwei Wang

To effectively reduce the visual tokens in Visual Large Language Models (VLLMs), we propose a novel approach called Window Token Concatenation (WiCo). Specifically, we employ a sliding window to concatenate spatially adjacent visual tokens.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Yifan Li , Wentao Bao , Botao Ye , Zhen Tan , Tianlong Chen , Huan Liu , Yu Kong

Improving the feature representation ability is the foundation of many whole slide pathological image (WSIs) tasks. Recent works have achieved great success in pathological-specific self-supervised learning (SSL). However, most of them only…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Zhimiao Yu , Tiancheng Lin , Yi Xu

The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and whole-slide image (WSI)-level models, limiting the integration…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Xuan Gong , Kai Zhang , Pingyi Chen , Ye Zhang , Zhongyi Shui , Tao Lin , Lin Yang

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

The visual projector serves as an essential bridge between the visual encoder and the Large Language Model (LLM) in a Multimodal LLM (MLLM). Typically, MLLMs adopt a simple MLP to preserve all visual contexts via one-to-one transformation.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Wentong Li , Yuqian Yuan , Jian Liu , Dongqi Tang , Song Wang , Jie Qin , Jianke Zhu , Lei Zhang

Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histopathology tissue is used for analysis. Because of the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Honglin Li , Yunlong Zhang , Chenglu Zhu , Jiatong Cai , Sunyi Zheng , Lin Yang

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Large Language Models (LLMs) have demonstrated remarkable proficiency in language comprehension and generation; however, their widespread adoption is constrained by substantial bandwidth and computational demands. While pruning and low-rank…

Computation and Language · Computer Science 2025-10-31 Zeliang Zong , Kai Zhang , Zheyang Li , Wenming Tan , Ye Ren , Yiyan Zhai , Jilin Hu

Whole Slide Imaging (WSI) has become an important topic during the last decade. Even though significant progress in both medical image processing and computational resources has been achieved, there are still problems in WSI that need to be…

Image and Video Processing · Electrical Eng. & Systems 2019-03-19 Wafa Chenni , Habib Herbi , Morteza Babaie , H. R. Tizhoosh

Existing Multimodal Large Language Models (MLLMs) process a large number of visual tokens, leading to significant computational costs and inefficiency. Instruction-related visual token compression demonstrates strong task relevance, which…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Lei Lei , Jie Gu , Xiaokang Ma , Chu Tang , Jingmin Chen , Tong Xu

Video large language models (Video-LLMs) face high computational costs due to large volumes of visual tokens. Existing token compression methods typically adopt a two-stage spatiotemporal compression strategy, relying on stage-specific…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Junhao Du , Jialong Xue , Anqi Li , Jincheng Dai , Guo Lu

Large language models (LLMs) increasingly rely on long-context modeling for tasks such as document understanding, code analysis, and multi-step reasoning. However, scaling context windows to the million-token level brings prohibitive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Jiale Cheng , Yusen Liu , Xinyu Zhang , Yulin Fei , Wenyi Hong , Ruiliang Lyu , Weihan Wang , Zhe Su , Xiaotao Gu , Xiao Liu , Yushi Bai , Jie Tang , Hongning Wang , Minlie Huang

Whole slide images (WSIs) are vital in digital pathology, enabling gigapixel tissue analysis across various pathological tasks. While recent advancements in multi-modal large language models (MLLMs) allow multi-task WSI analysis through…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Xinheng Lyu , Yuci Liang , Wenting Chen , Meidan Ding , Jiaqi Yang , Guolin Huang , Daokun Zhang , Xiangjian He , Linlin Shen

Digital pathology offers a groundbreaking opportunity to transform clinical practice in histopathological image analysis, yet faces a significant hurdle: the substantial file sizes of pathological Whole Slide Images (WSI). While current…

With the rapid advancement of pathology foundation models (FMs), the representation learning of whole slide images (WSIs) attracts increasing attention. Existing studies develop high-quality patch feature extractors and employ carefully…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yuxuan Chen , Jiawen Li , Jiali Hu , Xitong Ling , Tian Guan , Anjia Han , Yonghong He

Hyperscaling of data and parameter count in LLMs is yielding diminishing improvement when weighed against training costs, underlining a growing need for more efficient finetuning and inference without sacrificing performance. This is…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Moulik Choraria , Xinbo Wu , Akhil Bhimaraju , Nitesh Sekhar , Yue Wu , Xu Zhang , Prateek Singhal , Lav R. Varshney

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

The exponential growth of Large Multimodal Models (LMMs) has driven advancements in cross-modal reasoning but at significant computational costs. In this work, we focus on visual language models. We highlight the redundancy and inefficiency…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Yasmine Omri , Parth Shroff , Thierry Tambe

Histopathology Whole Slide Image (WSI) analysis serves as the gold standard for clinical cancer diagnosis in the daily routines of doctors. To develop computer-aided diagnosis model for WSIs, previous methods typically employ Multi-Instance…

Computer Vision and Pattern Recognition · Computer Science 2024-10-21 Honglin Li , Yunlong Zhang , Pingyi Chen , Zhongyi Shui , Chenglu Zhu , Lin Yang