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In the modern healthcare system, rapidly expanding costs/complexity, the growing myriad of treatment options, and exploding information streams that often do not effectively reach the front lines hinder the ability to choose optimal…

Artificial Intelligence · Computer Science 2018-10-09 Casey C. Bennett , Kris Hauser

The "black box" nature of Large Reasoning Models (LRMs) presents critical limitations in reliability and transparency, fueling the debate around the "illusion of thinking" and the challenge of state hallucinations in agentic systems. In…

Artificial Intelligence · Computer Science 2025-09-29 Antoni Guasch , Maria Isabel Valdez

The diagnosis of oral diseases presents a problematic clinical challenge, characterized by a wide spectrum of pathologies with overlapping symptomatology. To address this, we developed Clinical Semantic Intelligence (CSI), a novel…

Artificial Intelligence · Computer Science 2025-07-22 Mohammad Mashayekhi , Sara Ahmadi Majd , Arian AmirAmjadi , Parsa Hosseini

Multi-agent systems powered by Large Language Models face a critical challenge: agents communicate through natural language, leading to semantic drift, hallucination propagation, and inefficient token consumption. We propose G2CP…

Multiagent Systems · Computer Science 2026-02-24 Karim Ben Khaled , Davy Monticolo

This survey investigates how classical software design patterns can enhance the reliability and scalability of communication in Large Language Model (LLM)-driven agentic AI systems, focusing particularly on the Model Context Protocol (MCP).…

Software Engineering · Computer Science 2026-05-25 Anjana Sarkar , Soumyendu Sarkar

This paper establishes a fundamental convergence: Schema-Guided Dialogue (SGD) and the Model Context Protocol (MCP) represent two manifestations of a unified paradigm for deterministic, auditable LLM-agent interaction. SGD, designed for…

Artificial Intelligence · Computer Science 2026-03-06 Andreas Schlapbach

Model Context Protocol (MCP) servers enable AI applications to connect to external systems in a plug-and-play manner, but their rapid proliferation also introduces severe security risks. Unlike mature software ecosystems with rigorous…

Cryptography and Security · Computer Science 2025-09-30 Weibo Zhao , Jiahao Liu , Bonan Ruan , Shaofei Li , Zhenkai Liang

The Model Context Protocol (MCP) has emerged as a de facto standard for integrating Large Language Models with external tools, yet no formal security analysis of the protocol specification exists. We present the first rigorous security…

Cryptography and Security · Computer Science 2026-01-27 Narek Maloyan , Dmitry Namiot

Modern software-defined networks, such as Open Radio Access Network (O-RAN) systems, rely on artificial intelligence (AI)-powered applications running on controllers interfaced with the radio access network. To ensure that these AI…

Signal Processing · Electrical Eng. & Systems 2025-02-06 Seonghoon Yoo , Sangwoo Park , Petar Popovski , Joonhyuk Kang , Osvaldo Simeone

Large language models and autonomous AI agents have evolved rapidly, resulting in a diverse array of evaluation benchmarks, frameworks, and collaboration protocols. Driven by the growing need for standardized evaluation and integration, we…

Artificial Intelligence · Computer Science 2026-03-10 Mohamed Amine Ferrag , Norbert Tihanyi , Merouane Debbah

Bridging clinical diagnostic reasoning with AI remains a central challenge in medical imaging. We introduce MedCLM, an automated pipeline that converts detection datasets into large-scale medical visual question answering (VQA) data with…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Soo Yong Kim , Suin Cho , Vincent-Daniel Yun , Gyeongyeon Hwang

Medical experts may use Artificial Intelligence (AI) systems with greater trust if these are supported by contextual explanations that let the practitioner connect system inferences to their context of use. However, their importance in…

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

AI tools in pathology have improved screening throughput, standardized quantification, and revealed prognostic patterns that inform treatment. However, adoption remains limited because most systems still lack the human-readable reasoning…

Artificial Intelligence · Computer Science 2025-11-18 Yunqi Hong , Johnson Kao , Liam Edwards , Nein-Tzu Liu , Chung-Yen Huang , Alex Oliveira-Kowaleski , Cho-Jui Hsieh , Neil Y. C. Lin

Artificial intelligence (AI)-based computer perception (CP) technologies use mobile sensors to collect behavioral and physiological data for clinical decision-making. These tools can reshape how clinical knowledge is generated and…

Large language models hold considerable promise for supporting forensic investigations, but their widespread adoption is hindered by a lack of transparency, explainability, and reproducibility. This paper explores how the emerging Model…

Cryptography and Security · Computer Science 2025-06-03 Jan-Niclas Hilgert , Carlo Jakobs , Michael Külper , Martin Lambertz , Axel Mahr , Elmar Padilla

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

Machine Learning · Computer Science 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

Computation and Language · Computer Science 2024-05-13 Taeyoon Kwon , Kai Tzu-iunn Ong , Dongjin Kang , Seungjun Moon , Jeong Ryong Lee , Dosik Hwang , Yongsik Sim , Beomseok Sohn , Dongha Lee , Jinyoung Yeo

Recent advancements in Large Language Models (LLMs) and the introduction of the Model Context Protocol (MCP) have significantly expanded LLM agents' capability to interact dynamically with external tools and APIs. However, existing tool…

Computation and Language · Computer Science 2025-05-13 Elias Lumer , Anmol Gulati , Vamse Kumar Subbiah , Pradeep Honaganahalli Basavaraju , James A. Burke
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