English

MedCLM: Learning to Localize and Reason via a CoT-Curriculum in Medical Vision-Language Models

Computer Vision and Pattern Recognition 2025-10-07 v1 Artificial Intelligence Computation and Language Machine Learning

Abstract

Bridging clinical diagnostic reasoning with AI remains a central challenge in medical imaging. We introduce MedCLM, an automated pipeline that converts detection datasets into large-scale medical visual question answering (VQA) data with Chain-of-Thought (CoT) reasoning by linking lesion boxes to organ segmentation and structured rationales. These contextual signals enable medical vision-language models to generate question-answer pairs with step-by-step reasoning. To utilize this data effectively, we propose an Integrated CoT-Curriculum Strategy composed of an Easy stage with explicit lesion boxes for visual grounding, a Medium stage that encourages implicit localization, and a Hard stage for weakly supervised reasoning. Experimental results demonstrate that MedCLM attains state-of-the-art performance on several medical VQA benchmarks, providing a scalable framework for developing clinically aligned medical vision-language models.

Keywords

Cite

@article{arxiv.2510.04477,
  title  = {MedCLM: Learning to Localize and Reason via a CoT-Curriculum in Medical Vision-Language Models},
  author = {Soo Yong Kim and Suin Cho and Vincent-Daniel Yun and Gyeongyeon Hwang},
  journal= {arXiv preprint arXiv:2510.04477},
  year   = {2025}
}