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In this study, 18F-FDG PET/CT brain scans of 50 patients with head and neck malignant lesions were employed to systematically assess the relationship between the amount of injected dose (10%, 8%, 6%, 5%, 4%, 3%, 2%, and 1% of standard dose)…

Medical Physics · Physics 2021-03-22 Behnoush Sanaei , Reza Faghihi , Hossein Arabi

Deep learning-based positron emission tomography (PET) image denoising offers the potential to reduce radiation exposure and scanning time by transforming low-count images into high-count equivalents. However, existing methods typically…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Menghua Xia , Huidong Xie , Qiong Liu , Bo Zhou , Hanzhong Wang , Biao Li , Axel Rominger , Quanzheng Li , Ramsey D. Badawi , Kuangyu Shi , Georges El Fakhri , Chi Liu

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

Neoadjuvant chemotherapy (NAC) has become a standard clinical practice for tumor downsizing in breast cancer with 18F-FDG Positron Emission Tomography (PET). Our work aims to leverage PET imaging for the segmentation of breast lesions. The…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Tewele W. Tareke , Neree Payan , Alexandre Cochet , Laurent Arnould , Benoit Presles , Jean-Marc Vrigneaud , Fabrice Meriaudeau , Alain Lalande

Reducing scan time in Positron Emission Tomography (PET) imaging while maintaining high-quality images is crucial for minimizing patient discomfort and radiation exposure. Due to the limited size of datasets and distribution discrepancy…

Image and Video Processing · Electrical Eng. & Systems 2024-07-11 Yumin Kim , Gayoon Choi , Seong Jae Hwang

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fumio Hashimoto , Kuang Gong

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…

Positron Emission Tomography (PET) imaging is a vital tool in medical diagnostics, offering detailed insights into molecular processes within the human body. However, PET images often suffer from complicated noise, which can obscure…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Xuehua Ye , Hongxu Yang , Adam J. Schwarz

This paper evaluates the performance of supervised and unsupervised deep learning models for denoising positron emission tomography (PET) images in the presence of reduced acquisition times. Our experiments consider 212 studies (56908…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Ivan Kruzhilov , Stepan Kudin , Luka Vetoshkin , Elena Sokolova , Vladimir Kokh

LAFOV PET/CT has the potential to unlock new applications such as ultra-low dose PET/CT imaging, multiplexed imaging, for biomarker development and for faster AI-driven reconstruction, but further work is required before these can be…

Objective: Long-axial field-of-view (LAFOV) positron emission tomography (PET) systems allow higher sensitivity, with an increased number of detected lines of response induced by a larger angle of acceptance. However, this extended angle…

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Boxiao Yu , Kuang Gong

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang
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