LAFOV PET/CT has the potential to unlock new applications such as ultra-low dose PET/CT imaging, multiplexed imaging, for biomarker development and for faster AI-driven reconstruction, but further work is required before these can be deployed in clinical routine. LAFOV PET/CT has unrivalled sensitivity but has a spatial resolution of an equivalent scanner with a shorter axial field of view. AI approaches are increasingly explored as potential avenues to enhance image resolution.
@article{arxiv.2509.00304,
title = {Artificial Intelligence-Guided PET Image Reconstruction and Multi-Tracer Imaging: Novel Methods, Challenges, And Opportunities},
author = {Movindu Dassanayake and Alejandro Lopez and Andrew Reader and Gary J. R. Cook and Clemens Mingels and Arman Rahmim and Robert Seifert and Ian Alberts and Fereshteh Yousefirizi},
journal= {arXiv preprint arXiv:2509.00304},
year = {2025}
}