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Preclinical research and organ-dedicated applications require high-resolution positron emission tomography (PET) detectors to visualize small structures and understand biological processes at a finer level of detail. Current commercial…

This study performs a comprehensive evaluation of quantitative measurements as extracted from automated deep-learning-based segmentation methods, beyond traditional Dice Similarity Coefficient assessments, focusing on six quantitative…

Image and Video Processing · Electrical Eng. & Systems 2025-04-24 Obed Korshie Dzikunu , Amirhossein Toosi , Shadab Ahamed , Sara Harsini , Francois Benard , Xiaoxiao Li , Arman Rahmim

Deep image prior (DIP) has been successfully applied to positron emission tomography (PET) image restoration, enabling represent implicit prior using only convolutional neural network architecture without training dataset, whereas the…

Medical Physics · Physics 2024-04-23 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Keisuke Matsubara , Masanobu Ibaraki

In PET, the amount of relative (signal-dependent) noise present in different body regions can be significantly different and is inherently related to the number of counts present in that region. The number of counts in a region depends, in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ye Li , Jianan Cui , Junyu Chen , Guodong Zeng , Scott Wollenweber , Floris Jansen , Se-In Jang , Kyungsang Kim , Kuang Gong , Quanzheng Li

Automated segmentation of cancerous lesions in PET/CT scans is a crucial first step in quantitative image analysis. However, training deep learning models for segmentation with high accuracy is particularly challenging due to the variations…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Shadab Ahamed

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

Positron emission tomography (PET) scanners continue to increase sensitivity and axial coverage by adding an ever expanding array of block detectors. As they age, one or more block detectors may lose sensitivity due to a malfunction or…

Medical Physics · Physics 2019-10-17 William Whiteley , Jens Gregor

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

Low-count positron emission tomography (LCPET) imaging can reduce patients' exposure to radiation but often suffers from increased image noise and reduced lesion detectability, necessitating effective denoising techniques. Diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Yinchi Zhou , Huidong Xie , Menghua Xia , Qiong Liu , Bo Zhou , Tianqi Chen , Jun Hou , Liang Guo , Xinyuan Zheng , Hanzhong Wang , Biao Li , Axel Rominger , Kuangyu Shi , Nicha C. Dvorneka , Chi Liu

Fetal motion discernment utilizing spectral images extracted from accelerometric data incident on pregnant mothers abdomen has gained substantial attention in the state-of-the-art research. It is an essential practice to avoid adverse…

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. However, low-count PET scans often suffer from high image noise, which can negatively impact image…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Huidong Xie , Qiong Liu , Bo Zhou , Xiongchao Chen , Xueqi Guo , Chi Liu

Objective. This study investigates the best achievable performance of a brain-dedicated PET system with high resolution and sensitivity by evaluating different detector configurations, while maintaining a practical system design suitable…

Medical Physics · Physics 2026-02-26 Yuemeng Feng , Lisa Blackberg , Arkadiusz Sitek , Hamid Sabet

PET imaging is an invaluable tool in clinical settings as it captures the functional activity of both healthy anatomy and cancerous lesions. Developing automatic lesion segmentation methods for PET images is crucial since manual lesion…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Tanya Gatsak , Kumar Abhishek , Hanene Ben Yedder , Saeid Asgari Taghanaki , Ghassan Hamarneh

Purpose: The main purpose of this study was to assess the reliability of shape and heterogeneity features in both Positron Emission Tomography (PET) and low-dose Computed Tomography (CT) components of PET/CT. A secondary objective was to…

Computer Vision and Pattern Recognition · Computer Science 2016-10-06 Marie-Charlotte Desseroit , Florent Tixier , Wolfgang Weber , Barry A Siegel , Catherine Cheze Le Rest , Dimitris Visvikis , Mathieu Hatt

Hair artifacts in dermoscopic images present significant challenges for accurate skin lesion analysis, potentially obscuring critical diagnostic features in dermatological assessments. This work introduces a fine-tuned SegFormer model…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Asif Mohammed Saad , Umme Niraj Mahi

In clinical practice, radiologists are reliant on the lesion size when distinguishing metastatic from non-metastatic lesions. A prerequisite for lesion sizing is their detection, as it promotes the downstream assessment of tumor spread.…

Image and Video Processing · Electrical Eng. & Systems 2021-11-12 Tarun Mattikalli , Tejas Sudharshan Mathai , Ronald M. Summers

Accurate lesion segmentation in whole-body PET/CT scans is crucial for cancer diagnosis and treatment planning, but limited datasets often hinder the performance of automated segmentation models. In this paper, we explore the potential of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Lap Yan Lennon Chan , Chenxin Li , Yixuan Yuan

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

The escalating global cancer burden underscores the critical need for precise diagnostic tools in oncology. This research employs deep learning to enhance lesion segmentation in PET/CT imaging, utilizing a dataset of 900 whole-body…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Jiayi Liu , Qiaoyi Xue , Youdan Feng , Tianming Xu , Kaixin Shen , Chuyun Shen , Yuhang Shi

Accurate and automated lesion segmentation in Positron Emission Tomography / Computed Tomography (PET/CT) imaging is essential for cancer diagnosis and therapy planning. This paper presents a Swin Transformer UNet 3D (SwinUNet3D) framework…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Shovini Guha , Dwaipayan Nandi