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Background: A crucial initial processing step for quantitative PET/CT analysis is the segmentation of tumor lesions enabling accurate feature ex-traction, tumor characterization, oncologic staging, and image-based therapy response…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Ludovic Sibille , Xinrui Zhan , Lei Xiang

Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Ida Häggström , C. Ross Schmidtlein , Gabriele Campanella , Thomas J. Fuchs

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Lesion segmentation in PET/CT imaging is essential for precise tumor characterization, which supports personalized treatment planning and enhances diagnostic precision in oncology. However, accurate manual segmentation of lesions is…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Hamza Kalisch , Fabian Hörst , Ken Herrmann , Jens Kleesiek , Constantin Seibold

Although supervised convolutional neural networks (CNNs) often outperform conventional alternatives for denoising positron emission tomography (PET) images, they require many low- and high-quality reference PET image pairs. Herein, we…

Medical Physics · Physics 2021-09-29 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Hiroyuki Ohba , Ryosuke Ota , Etsuji Yoshikawa , Yasuomi Ouchi

In the domain of computer vision, Parameter-Efficient Tuning (PET) is increasingly replacing the traditional paradigm of pre-training followed by full fine-tuning. PET is particularly favored for its effectiveness in large foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-01-16 Jiaqi Huang , Zunnan Xu , Ting Liu , Yong Liu , Haonan Han , Kehong Yuan , Xiu Li

Patient motion during PET is inevitable. Its long acquisition time not only increases the motion and the associated artifacts but also the patient's discomfort, thus PET acceleration is desirable. However, accelerating PET acquisition will…

Image and Video Processing · Electrical Eng. & Systems 2023-02-15 Bo Zhou , Yu-Jung Tsai , Jiazhen Zhang , Xueqi Guo , Huidong Xie , Xiongchao Chen , Tianshun Miao , Yihuan Lu , James S. Duncan , Chi Liu

PET provides in vivo molecular and functional imaging capability that is crucial to studying the interaction of plant with changing environment at the whole-plant level. We have developed a dedicated plant PET imager that features high…

Instrumentation and Detectors · Physics 2014-09-22 Qiang Wang , Aswin J. Mathews , Ke Li , Jie Wen , Sergey Komarov , Joseph A. O'Sullivan , Yuan-Chuan Tai

Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Tzu-An Song , Samadrita Roy Chowdhury , Fan Yang , Joyita Dutta

Historically, patient datasets have been used to develop and validate various reconstruction algorithms for PET/MRI and PET/CT. To enable such algorithm development, without the need for acquiring hundreds of patient exams, in this paper we…

The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…

One of the major challenges in design and developing of PET, scanners are the presence of inactive areas between the detector blocks which degrade the image spatial resolution and leads to streaking artifacts especially when we employ…

Medical Physics · Physics 2019-06-19 Isaac Shiri , Peyman Sheikhzadeh , Mohammad Reza Ay

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

One of the most challenges in medical imaging is the lack of data and annotated data. It is proven that classical segmentation methods such as U-NET are useful but still limited due to the lack of annotated data. Using a weakly supervised…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Amine Amyar , Romain Modzelewski , Pierre Vera , Vincent Morard , Su Ruan

Low-count PET is an efficient way to reduce radiation exposure and acquisition time, but the reconstructed images often suffer from low signal-to-noise ratio (SNR), thus affecting diagnosis and other downstream tasks. Recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Bo Zhou , Huidong Xie , Qiong Liu , Xiongchao Chen , Xueqi Guo , Zhicheng Feng , Jun Hou , S. Kevin Zhou , Biao Li , Axel Rominger , Kuangyu Shi , James S. Duncan , Chi Liu

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong

Automatic lesion detection from computed tomography (CT) scans is an important task in medical imaging analysis. It is still very challenging due to similar appearances (e.g. intensity and texture) between lesions and other tissues, making…

Computer Vision and Pattern Recognition · Computer Science 2019-01-25 Youbao Tang , Ke Yan , Yuxing Tang , Jiamin Liu , Jing Xiao , Ronald M. Summers