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The application of deep learning to medical image segmentation has been hampered due to the lack of abundant pixel-level annotated data. Few-shot Semantic Segmentation (FSS) is a promising strategy for breaking the deadlock. However, a…
Training neural networks using limited annotations is an important problem in the medical domain. Deep Neural Networks (DNNs) typically require large, annotated datasets to achieve acceptable performance which, in the medical domain, are…
Accurate tumor segmentation in PET/CT images is crucial for computer-aided cancer diagnosis and treatment. The primary challenge lies in effectively integrating the complementary information from PET and CT images. In clinical settings, the…
Introduction: Terbium-149 ($^{149}$Tb) is a promising radionuclide for targeted $\alpha$ therapy that has a non-zero branching ratio (BR) for positron decay. However, its relatively low positron branching fraction and multiple prompt…
Computed Tomography (CT) plays an important role in monitoring radiation-induced Pulmonary Fibrosis (PF), where accurate segmentation of the PF lesions is highly desired for diagnosis and treatment follow-up. However, the task is challenged…
Positron emission tomography (PET) offers powerful functional imaging but involves radiation exposure. Efforts to reduce this exposure by lowering the radiotracer dose or scan time can degrade image quality. While using magnetic resonance…
$\textbf{Purpose}$: Automatic quantification of longitudinal changes in PET scans for lymphoma patients has proven challenging, as residual disease in interim-therapy scans is often subtle and difficult to detect. Our goal was to develop a…
Perceptual losses have emerged as powerful tools for training networks to enhance Low-Dose Computed Tomography (LDCT) images, offering an alternative to traditional pixel-wise losses such as Mean Squared Error, which often lead to…
Clinical SPECT-MPI images of 345 patients acquired from a dedicated cardiac SPECT in list-mode format were retrospectively employed to predict normal-dose images from low-dose data at the half, quarter, and one-eighth-dose levels. A…
Due to various physical degradation factors and limited counts received, PET image quality needs further improvements. The denoising diffusion probabilistic models (DDPM) are distribution learning-based models, which try to transform a…
Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…
The recovery of morphologically accurate anatomical images from deformed ones is challenging in ultrasound (US) image acquisition, but crucial to accurate and consistent diagnosis, particularly in the emerging field of computer-assisted…
Early cancer detection is crucial for improving patient outcomes, and 18F FDG PET/CT imaging plays a vital role by combining metabolic and anatomical information. Accurate lesion detection remains challenging due to the need to identify…
The Standardized Uptake Value (SUV) is a critical metric in positron emission tomography (PET) imaging, used to assess metabolic activity. However, calculating SUV from DICOM files presents challenges due to vendor-specific DICOM attributes…
To accurately quantify in vivo radiotracer uptake using Positron Emission Tomography (PET) is a challenging task due to low signal-to-noise ratio (SNR) and poor spatial resolution of PET camera along with the finite image sampling…
The remarkable success of deep learning methods in solving computer vision problems, such as image classification, object detection, scene understanding, image segmentation, etc., has paved the way for their application in biomedical…
Neurological Positron Emission Tomography (PET) is a critical imaging modality for diagnosing and studying neurodegenerative diseases like Alzheimer's disease. However, the inherent low spatial resolution of PET images poses significant…
Whole-body PET/CT scan is an important tool for diagnosing various malignancies (e.g., malignant melanoma, lymphoma, or lung cancer), and accurate segmentation of tumors is a key part for subsequent treatment. In recent years, CNN-based…
Supervised learning algorithms based on Convolutional Neural Networks have become the benchmark for medical image segmentation tasks, but their effectiveness heavily relies on a large amount of labeled data. However, annotating medical…
Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR…