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Large Language Models (LLMs) have shown extraordinary success across various text generation tasks; however, their potential for simple yet essential text classification remains underexplored, as LLM pre-training tends to emphasize…
Biomedical text mining is becoming increasingly important as the number of biomedical documents rapidly grows. With the progress in natural language processing (NLP), extracting valuable information from biomedical literature has gained…
Large language models (LLMs) encode extensive world knowledge through pre-training on massive datasets, which can then be fine-tuned for the question-answering (QA) task. However, effective strategies for fine-tuning LLMs for the QA task…
Despite their success at many natural language processing (NLP) tasks, large language models still struggle to effectively leverage knowledge for knowledge-intensive tasks, manifesting limitations such as generating incomplete, non-factual,…
Large Language Models (LLMs) have demonstrated impressive capability in different tasks and are bringing transformative changes to many domains. However, keeping the knowledge in LLMs up-to-date remains a challenge once pretraining is…
Large Language Models (LLMs) enhanced with external contexts, such as through retrieval-augmented generation (RAG), often face challenges in handling imperfect evidence. They tend to over-rely on external knowledge, making them vulnerable…
In recent years, developing compact and efficient large language models (LLMs) has emerged as a thriving area of research. Traditional Supervised Fine-Tuning (SFT), which relies on singular ground truth labels, often fails to capture…
Prompt learning is one of the most effective paradigms for adapting pre-trained vision-language models (VLMs) to the biomedical image classification tasks in few shot scenarios. However, most of the current prompt learning methods only used…
Large language models (LLMs) have become the cornerstone of modern AI. However, the existing paradigm of next-token prediction fundamentally limits their ability to form coherent, high-level concepts, making it a critical barrier to…
A common challenge towards the adaptability of Large Language Models (LLMs) is their ability to learn new languages over time without hampering the model's performance on languages in which the model is already proficient (usually English).…
Language models (LMs) pretrained on a large text corpus and fine-tuned on a downstream text corpus and fine-tuned on a downstream task becomes a de facto training strategy for several natural language processing (NLP) tasks. Recently, an…
Writing radiology reports from medical images requires a high level of domain expertise. It is time-consuming even for trained radiologists and can be error-prone for inexperienced radiologists. It would be appealing to automate this task…
Supervised fine-tuning (SFT) is a standard approach for adapting large language models to specialized domains, yet its application to protein sequence modeling and protein language models (PLMs) remains ad hoc. This is in part because…
Fine-tuning pretrained language models (LMs) without making any architectural changes has become a norm for learning various language downstream tasks. However, for non-language downstream tasks, a common practice is to employ task-specific…
The extraction and standardization of pharmacokinetic (PK) information from scientific literature remain significant challenges in computational pharmacology, which limits the reliability of data-driven models in drug development. Large…
Large language models are typically post-trained using supervised fine-tuning (SFT) and reinforcement learning (RL), yet effectively unifying efficient knowledge injection with robust generalization remains challenging. In this work, we…
Large language models (LLMs) such as ChatGPT are fine-tuned on large and diverse instruction-following corpora, and can generalize to new tasks. However, those instruction-tuned LLMs often perform poorly in specialized medical natural…
Despite their strong linguistic capabilities, Large Language Models (LLMs) are computationally demanding and require substantial resources for fine-tuning, which is unadapted to privacy and budget constraints of many healthcare settings. To…
Large Language Models (LLMs) are increasingly applied to tasks involving structured inputs such as graphs. Abstract Meaning Representations (AMRs), which encode rich semantics as directed graphs, offer a rigorous testbed for evaluating LLMs…
Instruction fine-tuning (IFT) can increase the informativeness of large language models (LLMs), but may reduce their truthfulness. This trade-off arises because IFT steers LLMs to generate responses containing long-tail knowledge that was…