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Spine disorders affect 619 million people globally and are a leading cause of disability, yet AI-assisted diagnosis remains limited by the lack of level-aware, multimodal datasets. Clinical decision-making for spine disorders requires…

Age is one of the major known risk factors for Alzheimer's Disease (AD). Detecting AD early is crucial for effective treatment and preventing irreversible brain damage. Brain age, a measure derived from brain imaging reflecting structural…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Jay Shah , Md Mahfuzur Rahman Siddiquee , Yi Su , Teresa Wu , Baoxin Li

The global population is aging rapidly, and aging is a major risk factor for various diseases. It is an important task to predict how each individual's brain will age, as the brain supports many human functions. This capability can greatly…

Neurons and Cognition · Quantitative Biology 2025-12-05 Yifan Li , Javad Sohankar , Ji Luo , Jing Li , Yi Su

Biological age scores are an emerging tool to characterize aging by estimating chronological age based on physiological biomarkers. Various scores have shown associations with aging-related outcomes. This study assessed the relation between…

Heterogeneity of brain diseases is a challenge for precision diagnosis/prognosis. We describe and validate Smile-GAN (SeMI-supervised cLustEring-Generative Adversarial Network), a novel semi-supervised deep-clustering method, which dissects…

The diagnosis, prognosis, and treatment of patients with musculoskeletal (MSK) disorders require radiology imaging (using computed tomography, magnetic resonance imaging(MRI), and ultrasound) and their precise analysis by expert…

Image and Video Processing · Electrical Eng. & Systems 2020-03-03 Ismail Irmakci , Syed Muhammad Anwar , Drew A. Torigian , Ulas Bagci

Spine image segmentation is crucial for clinical diagnosis and treatment of spine diseases. The complex structure of the spine and the high morphological similarity between individual vertebrae and adjacent intervertebral discs make…

Image and Video Processing · Electrical Eng. & Systems 2025-08-27 Dingwei Fan , Junyong Zhao , Chunlin Li , Mingliang Wang , Qi Zhu , Haipeng Si , Daoqiang Zhang , Liang Sun

Magnetic Resonance Imaging (MRI) is pivotal in radiology, offering non-invasive and high-quality insights into the human body. Precise segmentation of MRIs into different organs and tissues would be highly beneficial since it would allow…

In modern medical diagnostics, magnetic resonance imaging (MRI) is an important technique that provides detailed insights into anatomical structures. In this paper, we present a comprehensive methodology focusing on streamlining the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-25 Siddharth Jha , Zichen Gui , Benjamin Delbos , Richard Moreau , Arnaud Leleve , Irene Cheng

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

Quantitative Methods · Quantitative Biology 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

Patient-specific 3D spine models serve as a foundation for spinal treatment and surgery planning as well as analysis of loading conditions in biomechanical and biomedical research. Despite advancements in imaging technologies, the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Lara Blomenkamp , Ivanna Kramer , Sabine Bauer , Kevin Weirauch , Dietrich Paulus

Background and Objectives: This paper focuses on using AI to assess the cognitive function of older adults with mild cognitive impairment or mild dementia using physiological data provided by a wearable device. Cognitive screening tools are…

Neurons and Cognition · Quantitative Biology 2025-11-10 Assma Habadi , Milos Zefran , Lijuan Yin , Woojin Song , Maria Caceres , Elise Hu , Naoko Muramatsu

As the number of dementia patients rises, the need for accurate diagnostic procedures rises as well. Current methods, like using an MRI scan, rely on human input, which can be inaccurate. However, the decision logic behind machine learning…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Tyler Morris , Ziming Liu , Longjian Liu , Xiaopeng Zhao

Scoliosis is a sideways curvature of the spine that most often is diagnosed among young teenagers. It dramatically affects the quality of life, which can cause complications from heart and lung injuries in severe cases. The current gold…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Yen Hoang Nguyen

Background: Alzheimers disease is a progressive neurodegenerative disorder and the main cause of dementia in aging. Hippocampus is prone to changes in the early stages of Alzheimers disease. Detection and observation of the hippocampus…

Image and Video Processing · Electrical Eng. & Systems 2021-06-17 Hossein Yousefi-Banaem , Saber Malekzadeh

Prediction of the cognitive evolution of a person susceptible to develop a neurodegenerative disorder is crucial to provide an appropriate treatment as soon as possible. In this paper we propose a 3D siamese network designed to extract…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Cecilia Ostertag , Marie Beurton-Aimar , Thierry Urruty

Medical imaging plays an important role in the medical sector in identifying diseases. X-ray, computed tomography (CT) scans, and magnetic resonance imaging (MRI) are a few examples of medical imaging. Most of the time, these imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Mosabbir Bhuiyan , MD Abdullah Al Nasim , Sarwar Saif , Kishor Datta Gupta , Md Jahangir Alam , Sajedul Talukder

With the advent of deep learning algorithms, fully automated radiological image analysis is within reach. In spine imaging, several atlas- and shape-based as well as deep learning segmentation algorithms have been proposed, allowing for…

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique that records neural activations in the brain by capturing the blood oxygen level in different regions based on the task performed by a subject. Given fMRI data, the…

Computer Vision and Pattern Recognition · Computer Science 2021-09-21 Ashish Jaiswal , Ashwin Ramesh Babu , Mohammad Zaki Zadeh , Fillia Makedon , Glenn Wylie

In medical imaging, segmentation and localization of spinal tumors in three-dimensional (3D) space pose significant computational challenges, primarily stemming from limited data availability. In response, this study introduces a novel data…

Image and Video Processing · Electrical Eng. & Systems 2024-05-08 Rikathi Pal , Sudeshna Mondal , Aditi Gupta , Priya Saha , Somoballi Ghoshal , Amlan Chakrabarti , Susmita Sur-Kolay
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