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Purpose. To present SPINEPS, an open-source deep learning approach for semantic and instance segmentation of 14 spinal structures (ten vertebra substructures, intervertebral discs, spinal cord, spinal canal, and sacrum) in whole body T2w…

We present SpineTrack, the first comprehensive dataset for 2D spine pose estimation in unconstrained settings, addressing a crucial need in sports analytics, healthcare, and realistic animation. Existing pose datasets often simplify the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Muhammad Saif Ullah Khan , Stephan Krauß , Didier Stricker

In this study, we propose the use of persistent homology -- specifically Betti curves for brain age prediction and for distinguishing between healthy and pathological aging. The proposed framework is applied to 100 structural MRI scans from…

Neurons and Cognition · Quantitative Biology 2025-11-11 Debanjali Bhattacharya , Neelam Sinha

Deep learning techniques have demonstrated great potential for accurately estimating brain age by analyzing Magnetic Resonance Imaging (MRI) data from healthy individuals. However, current methods for brain age estimation often directly…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Fanzhe Yan , Gang Yang , Yu Li , Aiping Liu , Xun Chen

Predicting an individual's aging trajectory is a central challenge in preventative medicine and bioinformatics. While machine learning models can predict chronological age from biomarkers, they often fail to capture the dynamic,…

Machine Learning · Computer Science 2025-08-14 Nazira Dunbayeva , Yulong Li , Yutong Xie , Imran Razzak

Biomechanical modeling of tissue deformation can be used to simulate different scenarios of longitudinal brain evolution. In this work,we present a deep learning framework for hyper-elastic strain modelling of brain atrophy, during healthy…

Neurons and Cognition · Quantitative Biology 2021-08-19 Mariana Da Silva , Carole H. Sudre , Kara Garcia , Cher Bass , M. Jorge Cardoso , Emma C. Robinson

Poor sitting habits have been identified as a risk factor to musculoskeletal disorders and lower back pain especially on the elderly, disabled people, and office workers. In the current computerized world, even while involved in leisure or…

Machine Learning · Computer Science 2022-01-11 Tariku Adane Gelaw , Misgina Tsighe Hagos

Osteoporosis silently erodes skeletal integrity worldwide; however, early detection through imaging can prevent most fragility fractures. Artificial intelligence (AI) methods now mine routine Dual-energy X-ray Absorptiometry (DXA), X-ray,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-02 Abdul Rahman , Bumshik Lee

INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…

Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative…

Functional properties of neurons are strongly coupled with their morphology. Changes in neuronal activity alter morphological characteristics of dendritic spines. First step towards understanding the structure-function relationship is to…

Computer Vision and Pattern Recognition · Computer Science 2016-07-20 Muhammad Usman Ghani , Ertunc Erdil , Sumeyra Demir Kanik , Ali Ozgur Argunsah , Anna Felicity Hobbiss , Inbal Israely , Devrim Unay , Tolga Tasdizen , Mujdat Cetin

Cervical spondylosis, a complex and prevalent condition, demands precise and efficient diagnostic techniques for accurate assessment. While MRI offers detailed visualization of cervical spine anatomy, manual interpretation remains…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Lianming Wu , Kun Wang , Jianqi Sun , Hongxing Shen

Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Mohammad Rafsan , Tamer Oraby , Upal Roy , Sanjeev Kumar , Hansapani Rodrigo

As the global population continues to age, there is an increasing demand for ways to accurately quantify the biological processes underlying aging. Biological age, unlike chronological age, reflects an individual's physiological state,…

Quantitative Methods · Quantitative Biology 2025-08-29 Jared A Kushner , Mohit Pandey , Sandeep , S Kohli

Accurate and reliable registration of longitudinal spine images is essential for assessment of disease progression and surgical outcome. Implementing a fully automatic and robust registration is crucial for clinical use, however, it is…

One of the major difficulties in medical image segmentation is the high variability of these images, which is caused by their origin (multi-centre), the acquisition protocols (multi-parametric), as well as the variability of human anatomy,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-09 Jhon Jairo Saenz-Gamboa , Julio Domenech , Antonio Alonso-Manjarrés , Jon A. Gómez , Maria de la Iglesia-Vayá

Motion-related artifacts are inevitable in Magnetic Resonance Imaging (MRI) and can bias automated neuroanatomical metrics such as cortical thickness. These biases can interfere with statistical analysis which is a major concern as motion…

Image and Video Processing · Electrical Eng. & Systems 2025-06-11 Charles Bricout , Samira Ebrahimi Kahou , Sylvain Bouix

The spinal angle is an important indicator of body balance. It is important to restore the 3D shape of the human body and estimate the spine center line. Existing mul-ti-image-based body restoration methods require expensive equipment and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Sehyun Kim , Hye Jun Lee , Jiwoo Lee , Changgyun Kim , Taemin Lee

Brain Age (BA) estimation via Deep Learning has become a strong and reliable bio-marker for brain health, but the black-box nature of Neural Networks does not easily allow insight into the features of brain ageing.We trained a ResNet model…

Neurons and Cognition · Quantitative Biology 2022-07-26 Daniel Taylor , Jonathan Shock , Deshendran Moodley , Jonathan Ipser , Matthias Treder

This paper introduces SpineFM, a novel pipeline that achieves state-of-the-art performance in the automatic segmentation and identification of vertebral bodies in cervical and lumbar spine radiographs. SpineFM leverages the regular geometry…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Samuel J. Simons , Bartłomiej W. Papież