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In many laboratories, conventional bright-field transmission microscopes are available to study the structure and organization principles of fibrous tissue samples, but they usually provide only 2D information. To access the third…

We propose a dataset-based photonic simulation framework for multimode waveguide design, enabling ultra-fast simulations with high accuracy. Compared to conventional approaches, our method offers two to three orders of magnitude speed-up in…

Optics · Physics 2025-11-11 Jaesung Song , Young-Ik Sohn

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

The acousto-optic interaction known as stimulated Brillouin scattering (SBS) has emerged as fundamental principles for realizing crucial components and functionalities in integrated photonics. However, the main challenge of integrated…

Optics · Physics 2024-02-08 Peng Lei , Mingyu Xu , Yunhui Bai , Zhangyuan Chen , Xiaopeng Xie

Consumer-grade printers are widely available, but their ability to print complex objects is limited. Therefore, new designs need to be discovered that serve the same function, but are printable. A representative such problem is to produce a…

Neural and Evolutionary Computing · Computer Science 2018-04-20 Cem C. Tutum , Supawit Chockchowwat , Etienne Vouga , Risto Miikkulainen

Noise plays a crucial role in the regulation of cellular and organismal function and behavior. Exploring noise's impact is key to understanding fundamental biological processes, such as gene expression, signal transduction, and the…

Molecular Networks · Quantitative Biology 2025-12-16 Chuanbo Liu , Yu Fu , Lu Lin , Elliot L. Elson , Jin Wang

Organic electrochemical transistors (OECTs) are currently being investigated for various applications, ranging from sensors to logics and neuromorphic hardware. The fabrication process must be compatible with flexible and scalable digital…

Advances in silicon photonics have resulted in rapidly increasing complexity of integrated circuits. New methods are desirable that allow direct characterization of individual optical components in-situ, without the need for additional…

Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental…

Fluid Dynamics · Physics 2026-05-25 Job van Essen , Ahmed Sharaf , Denzel Hopman , Selene Pirola , Paola Fanzio

Printed electronics have gained significant traction in recent years, presenting a viable path to integrating computing into everyday items, from disposable products to low-cost healthcare. However, the adoption of computing in these…

Hardware Architecture · Computer Science 2025-03-28 Panagiotis Chaidos , Giorgos Armeniakos , Sotirios Xydis , Dimitrios Soudris

Photonic brain-inspired platforms are emerging as novel analog computing devices, enabling fast and energy-efficient operations for machine learning. These artificial neural networks generally require tailored optical elements, such as…

Emerging Technologies · Computer Science 2021-07-30 Davide Pierangeli , Giulia Marcucci , Claudio Conti

Topological plasmonics offers new ways to manipulate light by combining concepts from topology and plasmonics, similar to topological edge states in photonics. However, designing such topological states remains challenging due to the…

Optics · Physics 2025-07-15 Fatemeh Davoodi

In additive manufacturing (AM), particularly for laser-based metal AM, process optimization is crucial to the quality of products and the efficiency of production. The identification of optimal process parameters out of a vast parameter…

Materials Science · Physics 2024-07-25 Xiao Shang , Evelyn Li , Ajay Talbot , Haitao Wen , Tianyi Lyu , Jiahui Zhang , Yu Zou

Stereolithographic 3D-printing (SLA) permits facile fabrication of high-precision microfluidic and lab-on-a-chip devices. SLA photopolymers often yield parts with low mechanical compliancy in sharp contrast to elastomers such as…

Materials Science · Physics 2024-01-18 Alireza Ahmadianyazdi , Isaac J. Miller , Albert Folch

We describe a method for imaging 3D objects in a tomographic configuration implemented by training an artificial neural network to reproduce the complex amplitude of the experimentally measured scattered light. The network is designed such…

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

We demonstrate, for the first time, the applicability of 3D printing technique to the manufacture of scintillation detectors. We report of a formulation, usable in stereolithographic printing, that exhibits scintillation efficiency on the…

Materials Science · Physics 2014-06-20 Y. Mishnayot , M. Layani , I. Cooperstein , S. Magdassi , G. Ron

Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…

This paper reports on the derivation and implementation of a shape optimization procedure for the minimization of hemolysis induction in biomedical devices. Hemolysis is a blood damaging phenomenon that may occur in mechanical…

Fluid Dynamics · Physics 2021-01-27 Georgios Bletsos , Niklas Kühl , Thomas Rung

Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

Tissues and Organs · Quantitative Biology 2015-12-22 Richard J. McMurtrey