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Accurate neuronavigation is critical for effective transcranial magnetic stimulation (TMS), as stimulation outcomes depend directly on precise coil placement. Existing neuronavigation systems are often costly, complex, and prone to tracking…

Human-Computer Interaction · Computer Science 2026-01-26 Xuyi Hu , Ke Ma , Siwei Liu , Per Ola Kristensson , Stefan Goetz

The fast-growing field of soft matter research requires increasingly sophisticated tools for experimental studies. One of the oldest and most widely used tools to study soft matter systems is optical microscopy. Recent advances in optical…

Soft Condensed Matter · Physics 2011-08-17 Taewoo Lee , Bohdan Senyuk , Rahul P. Trivedi , Ivan I. Smalyukh

The human brain has immense learning capabilities at extreme energy efficiencies and scale that no artificial system has been able to match. For decades, reverse engineering the brain has been one of the top priorities of science and…

The scarcity of organs for transplant has led to large waiting lists of very sick patients. In drug development, the time required for human trials greatly increases the time to market. Drug companies are searching for alternative…

Tissues and Organs · Quantitative Biology 2015-07-28 Ali Bakhshinejad , Roshan M D'Souza

Metasurfaces have achieved fruitful results in tailoring complexing light fields in free space. However, a systematic investigation on applying the concept of meta-optics to completely control waveguide modes is still elusive. Here we…

Optics · Physics 2021-11-04 Yuan Meng , Tiantian He , Zhoutian Liu , Futai Hu , Qirong Xiao , Qiang Liu , Mali Gong

Laser scanning microscopy enables the acquisition of 3D data in biomedical research. A fundamental challenge in visualizing 3D data is that common flat-panel displays, being 2D in nature, cannot faithfully reproduce light fields. Recent…

Graphics · Computer Science 2025-05-26 Yong Wan , Holly A. Holman , Charles Hansen

A method based on the particle swarm optimization (PSO) algorithm is presented to design quasi-two-dimensional (Q2D) materials. With this development, various single-layer and bi-layer materials in C, Si, Ge, Sn, and Pb were predicted. A…

Materials Science · Physics 2015-01-20 Wei Luo , Yanming Ma , Xingao Gong , Hongjun Xiang

Light activated local stimulation and sensing of biological cells offers enormous potential for minimally invasive bioelectronic interfaces. Organic semiconductors are a promising material class to achieve this kind of transduction due to…

Microscopy and optical imaging are drastically limited by the inhomogeneities encountered by the light while propagating from the object of interest to the detection system. In this context, adaptive optics and wavefront manipulation are…

Optics · Physics 2017-01-23 Diego Di Battista

Dense and efficient circuits with component sizes approaching the physical limit is the hallmark of high performance integration. However, current fabrication technology is mostly constraint to 2D lithography, and thermal energy dissipation…

Optics · Physics 2021-12-15 Adria Grabulosa , Johnny Moughames , Xavier Porte , Daniel Brunner

Optoionics, a promising new field that aims at controlling ion dynamics using light, links photovoltaic power generation with electrochemical charge storage. This has the potential to drive and accelerate the energy revolution by utilizing…

Materials Science · Physics 2025-03-11 Matteo Rinaldi , Matthias Kick , Karsten Reuter , Christian Carbogno

Optimizing solution-processed organic solar cells is a complex task due to the vast parameter space in organic photovoltaics (OPV). Classical Edisonian or one-variable-at-a-time (OVAT) optimization approaches are laborious, time-consuming,…

Efficient design and discovery of target-driven molecules is a critical step in facilitating lead optimization in drug discovery. Current approaches to develop molecules for a target protein are intuition-driven, hampered by slow iterative…

Machine Learning · Computer Science 2022-05-24 Andrew D. McNaughton , Mridula S. Bontha , Carter R. Knutson , Jenna A. Pope , Neeraj Kumar

Coded-illumination can enable quantitative phase microscopy of transparent samples with minimal hardware requirements. Intensity images are captured with different source patterns and a non-linear phase retrieval optimization reconstructs…

Signal Processing · Electrical Eng. & Systems 2019-02-07 Michael R. Kellman , Emrah Bostan , Nicole Repina , Laura Waller

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

We study the optically-induced growth and interaction of self-written waveguides in a photopolymerizable resin. We investigate experimentally how the interaction depends on the mutual coherence and relative power of the input beams, and…

Pattern Formation and Solitons · Physics 2009-04-01 Satoru Shoji , Satoshi Kawata , Andrey A. Sukhorukov , Yuri S. Kivshar

Medical imaging phantoms are widely used for validation and verification of imaging systems and algorithms in surgical guidance and radiation oncology procedures. Especially, for the performance evaluation of new algorithms in the field of…

On-chip photonic processors for neural networks have potential benefits in both speed and energy efficiency but have not yet reached the scale at which they can outperform electronic processors. The dominant paradigm for designing on-chip…

Photonics integrated circuitry would benefit considerably from the ability to arbitrarily control waveguide cross-sections with high precision and low loss, in order to provide more degrees of freedom in manipulating propagating light.…

While RNA technologies hold immense therapeutic potential in a range of applications from vaccination to gene editing, the broad implementation of these technologies is hindered by the challenge of delivering these agents effectively. Lipid…

Biomolecules · Quantitative Biology 2023-08-30 Daisy Yi Ding , Yuhui Zhang , Yuan Jia , Jiuzhi Sun