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We present a method for determining the 3D intensity distribution of directed laser radiation with micrometer resolution in restricted volumes. Our method is based on in-coupling and guiding properties of optical fibers, with the current…

Optics · Physics 2013-02-14 Yevhen Miroshnychenko , Otto Nielsen , Aske Thorsen , Michael Drewsen

A method of controllable light delivery to retinal rod cells using an optical fiber is described. Photo-induced current of the living rod cells was measured with the suction electrode technique. The approach was tested with measurements…

Biological Physics · Physics 2013-08-07 Nigel Sim , Dmitri Bessarab , C. Michael Jones , Leonid A. Krivitsky

Efficient optimization of topology and raster angle has shown unprecedented enhancements in the mechanical properties of 3D printed materials. Topology optimization helps reduce the waste of raw material in the fabrication of 3D printed…

Graphics · Computer Science 2022-06-08 Ahmed Moter , Mohamed Abdelhamid , Aleksander Czekanski

Microfluidic valves play a key role within microfluidic systems by regulating fluid flow through distinct microchannels, enabling many advanced applications in medical diagnostics, lab-on-chips, and laboratory automation. While microfluidic…

Materials Science · Physics 2023-12-19 Tinku Supakar , David Space , Sophy Meija , Rou Yu Tan , Jeffrey R. Alston , Eric A. Josephs

A customizable method (OPTIKS) for designing fast trajectory-constrained gradient waveforms with optimized time domain properties was developed. Given a specified multidimensional k-space trajectory, the method optimizes traversal speed…

Systems and Control · Electrical Eng. & Systems 2025-12-08 Matthew A. McCready , Xiaozhi Cao , Kawin Setsompop , John M. Pauly , Adam B. Kerr

The optical nanocircuit concept provides a predictive framework analogous to an electric RLC circuit, where induced dipoles in plasmonic nanoparticle (NPs), ohmic losses in NPs, and dielectric gaps serve as inductors (L), capacitors (C),…

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

This study reports the successful fabrication of high-positive refractive index change waveguides, exceeding 0.02 in fluoride glasses, marking a significant advancement in integrated optical components for visible to mid-infrared…

In the intact brain, neural activity can be recorded using sensing electrodes and manipulated using light stimulation. Silicon probes with integrated electrodes and micro-LEDs enable the detection and control of neural activity using a…

Signal Processing · Electrical Eng. & Systems 2022-11-28 Alexander Tarnavsky Eitan , Shirly Someck , Mario Zajac , Eran Socher , Eran Stark

Surface plasmon resonances generated in metallic nanostructures can be utilized to tailor electromagnetic fields. The precise spatial arrangement of such structures can result in surprising optical properties that are not found in any…

Endoscopic optical coherence tomography (OCT) is a valuable tool for providing diagnostic images of internal organs and guiding interventions in real time. Miniaturized OCT endoscopes are essential for imaging small and convoluted luminal…

Instrumentation and Detectors · Physics 2023-11-28 Chao Xu , Xin Guan , Syeda Aimen Abbasi , Neng Xia , To Ngai , Li Zhang , Ho-Pui Ho , Sze Hang Calvin Ng , Wu Yuan

Ultrathin meta-optics offer unmatched, multifunctional control of light. Next-generation optical technologies, however, demand unprecedented performance. This will likely require design algorithms surpassing the capability of human…

Optics · Physics 2021-04-06 Shane Colburn , Arka Majumdar

Precise spatial and temporal manipulation of neural activity in specific genetically defined cell populations is now possible with the advent of optogenetics. The emerging field of optogenetics consists of a set of naturally-occurring and…

Neurons and Cognition · Quantitative Biology 2012-08-15 Shinya Nakamura , Michael V. Baratta , Matthew B. Pomrenze , Samuel D. Dolzani , Donald C. Cooper

By design access to laser wavelength, especially with integrated photonics, is critical to advance quantum sensors like optical clocks and quantum-information systems, and open opportunities in optical communication. Semiconductor-laser…

Advances in imaging technology now provide us with detailed 3D data on gene expression patterns in developing embryos. This information can be used to build predictive mathematical models of embryogenesis. Current modelling approaches are,…

Quantitative Methods · Quantitative Biology 2014-06-11 Britta Velten , Erkan Uenal , Dagmar Iber

Optical processors, built with "optical neurons", can efficiently perform high-dimensional linear operations at the speed of light. Thus they are a promising avenue to accelerate large-scale linear computations. With the current advances in…

An in-vitro cell culture system is used for biological discoveries and hypothesis-driven research on a particular cell type to understand mechanistic or test pharmaceutical drugs. Conventional in-vitro cultures have been applied to primary…

Image and Video Processing · Electrical Eng. & Systems 2023-01-09 Alireza Ranjbaran , Azadeh Nazemi

Integrated optical devices able to control light matter interactions on the nanoscale have attracted the attention of the scientific community in recent years. However, most of these devices are based on silicon waveguides, limiting their…

Tomographic Volumetric Additive Manufacturing(TVAM) is a novel manufacturing method that allows for the fast creation of objects of complex geometry in layerless fashion. The process is based on the solidification of photopolymer that…

Computational Engineering, Finance, and Science · Computer Science 2026-02-13 Nicole Pellizzon , Richard Huber , Jon Spangenberg , Jakob Sauer Jørgensen

An efficient electro-optical modulation has been demonstrated here by using an edge plasmon mode specific for the hybrid plasmonic waveguide. Our approach addresses a major obstacle of the integrated microwave photonics caused by the…

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