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We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…

Instrumentation and Detectors · Physics 2009-08-03 P. -E. Vert , J. Lecoq , G. Montarou , N. Pauna , B. Joly , M. Boutemeur , H. Mathez , R. Gaglione , P. Le Dû

Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fumio Hashimoto , Kuang Gong

Positron emission tomography (PET) is an advanced medical imaging technique that plays a crucial role in non-invasive clinical diagnosis. However, while reducing radiation exposure through low-dose PET scans is beneficial for patient…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Bin Huang , Xubiao Liu , Lei Fang , Qiegen Liu , Bingxuan Li

Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applications. The interpretation of FDG-PET data requires…

Tissues and Organs · Quantitative Biology 2020-01-22 Michele Piana , Giacomo Caviglia , Sara Sommariva

In oncology, Positron Emission Tomography-Computed Tomography (PET/CT) is widely used in cancer diagnosis, staging, and treatment monitoring, as it combines anatomical details from CT with functional metabolic activity and molecular marker…

In this paper, we review physics- and data-driven reconstruction techniques for simultaneous positron emission tomography (PET) / magnetic resonance imaging (MRI) systems, which have significant advantages for clinical imaging of cancer,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Abhejit Rajagopal , Andrew P. Leynes , Nicholas Dwork , Jessica E. Scholey , Thomas A. Hope , Peder E. Z. Larson

A major strength of iterative algorithms used in positron emission tomography (PET) lies in their abilities to introduce precise models of the physics at play, which includes the statistical nature of the detection processes, and a detailed…

Medical Physics · Physics 2022-04-26 Adrien Hourlier , Debora Giovagnoli , Virgile Bekaert , Frederic Boisson , David Brasse

Parameter-efficient fine-tuning (PEFT) has emerged as a promising paradigm for adapting pretrained models under limited data conditions. However, most existing PEFT methods are designed for matrix-structured parameters and are not well…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Guanghua He , Hancan Zhu , Gaohang Yu , An Zhang

Synthetic PET images are valuable for quantitative imaging workflow development, scalable virtual imaging trials, and deep learning model training, but conventional physics-based simulation approaches are computationally intensive, limited…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Suya Li , Kaushik Dutta , Debojyoti Pal , Jingqin Luo , Kooresh I. Shoghi

In oncology, Positron Emission Tomography imaging is widely used in diagnostics of cancer metastases, in monitoring of progress in course of the cancer treatment, and in planning radiotherapeutic interventions. Accurate and reproducible…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Jakub Czakon , Filip Drapejkowski , Grzegorz Zurek , Piotr Giedziun , Jacek Zebrowski , Witold Dyrka

The purpose of the presented investigations is to design, construct and establish the characteristic performance of the Jagiellonian Positron Emission Mammography(J-PEM), being designed for the detection and diagnosis of breast cancer. Its…

Medical Physics · Physics 2020-02-19 Shivani , Elżbieta Luczyńska , Sylwia Heinze , Paweł Moskal

This work is the second part of a simulation study investigating the processing of densely packed and moving granular assemblies by positron emission particle tracking (PEPT). Since medical PET scanners commonly used for PEPT are very…

We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…

Motivation: Alzheimer's Disease hallmarks include amyloid-beta deposits and brain atrophy, detectable via PET and MRI scans, respectively. PET is expensive, invasive and exposes patients to ionizing radiation. MRI is cheaper, non-invasive,…

Image and Video Processing · Electrical Eng. & Systems 2024-05-06 Fernando Vega , Abdoljalil Addeh , M. Ethan MacDonald

Images from Positron Emission Tomography (PET) deliver functional data such as perfusion and metabolism. On the other hand, images from Magnetic Resonance Imaging (MRI) provide information describing anatomical structures. Fusing the…

Image and Video Processing · Electrical Eng. & Systems 2018-06-19 Hiliwi Leake Kidane , Stephanie Bricq , Alain Lalande

Studies of the human brain during natural activities, such as locomotion, would benefit from the ability to image deep brain structures during these activities. While Positron Emission Tomography (PET) can image these structures, the bulk…

Robotics · Computer Science 2023-11-30 Junxiang Wang , Iulian I. Iordachita , Peter Kazanzides

Simultaneous functional PET/MR (sf-PET/MR) presents a cutting-edge multimodal neuroimaging technique. It provides an unprecedented opportunity for concurrently monitoring and integrating multifaceted brain networks built by spatiotemporally…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Luoyu Wang , Yitian Tao , Qing Yang , Yan Liang , Siwei Liu , Hongcheng Shi , Dinggang Shen , Han Zhang

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…