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Positron emission tomography (PET) is an important modality for diagnosing diseases such as cancer and Alzheimer's disease, capable of revealing the uptake of radiolabeled molecules that target specific pathological markers of the diseases.…

Medical Physics · Physics 2025-01-17 Hsin-Hsiung Huang , Zheyuan Zhu , Slun Booppasiri , Zhuo Chen , Shuo Pang , Chien-Min Kao

Artificial intelligence (AI) has significant potential to positively impact and advance medical imaging, including positron emission tomography (PET) imaging applications. AI has the ability to enhance and optimize all aspects of the PET…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Arkadiusz Sitek , Sangtae Ahn , Evren Asma , Adam Chandler , Alvin Ihsani , Sven Prevrhal , Arman Rahmim , Babak Saboury , Kris Thielemans

Positron Emission Tomography (PET) is now regarded as the gold standard for the diagnosis of Alzheimer's Disease (AD). However, PET imaging can be prohibitive in terms of cost and planning, and is also among the imaging techniques with the…

Tumor segmentation in medical imaging is crucial and relies on precise delineation. Fluorodeoxyglucose Positron-Emission Tomography (FDG-PET) is widely used in clinical practice to detect metabolically active tumors. However, FDG-PET scans…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Matthias Hadlich , Zdravko Marinov , Rainer Stiefelhagen

Tau positron emission tomography (PET) is a critical diagnostic modality for Alzheimer's disease (AD) because it visualizes and quantifies neurofibrillary tangles, a hallmark of AD pathology. However, its widespread clinical adoption is…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Jin Young Kim , Jeremy Hudson , Jeongchul Kim , Qing Lyu , Christopher T. Whitlow

INTRODUCTION: Quantification of amyloid plaques (A), neurofibrillary tangles (T2), and neurodegeneration (N) using PET and MRI is critical for Alzheimer's disease (AD) diagnosis and prognosis. Existing pipelines face limitations regarding…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Pierrick Coupé , Boris Mansencal , Floréal Morandat , Sergio Morell-Ortega , Nicolas Villain , Jose V. Manjón , Vincent Planche

Medical image segmentation is referred to the segmentation of known anatomic structures from different medical images. Normally, the medical data researches are more complicated and an exclusive structures. This computer aided diagnosis is…

Computer Vision and Pattern Recognition · Computer Science 2013-03-05 A. Meena , K. Raja

Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…

Positron emission tomography (PET) is a well-established functional imaging technique for diagnosing brain disorders. However, PET's high costs and radiation exposure limit its widespread use. In contrast, magnetic resonance imaging (MRI)…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Positron emission tomography (PET) is a key nuclear medicine imaging modality that visualizes radiotracer distributions to quantify in vivo physiological and metabolic processes, playing an irreplaceable role in disease management. Despite…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Yichi Zhang , Le Xue , Wenbo Zhang , Lanlan Li , Feiyang Xiao , Yuchen Liu , Xiaohui Zhang , Hongwei Zhang , Shuqi Wang , Gang Feng , Liling Peng , Xin Gao , Yuanfan Xu , Yuan Qi , Kuangyu Shi , Hong Zhang , Yuan Cheng , Mei Tian , Zixin Hu

Uncompressed clinical data from modern positron emission tomography (PET) scanners are very large, exceeding 350 million data points (projection bins). The last decades have seen tremendous advancements in mathematical imaging tools many of…

Medical Physics · Physics 2020-01-08 Matthias J. Ehrhardt , Pawel Markiewicz , Carola-Bibiane Schönlieb

Most radiotracers used in dynamic positron emission tomography (PET) scanning act in a linear time-invariant fashion so that the measured time-course data are a convolution between the time course of the tracer in the arterial supply and…

Positron Emission Tomography (PET) is a crucial tool in medical imaging, particularly for diagnosing diseases like cancer and Alzheimer's. The advent of Positronium Lifetime Imaging (PLI) has opened new avenues for assessing the tissue…

Medical Physics · Physics 2024-03-25 Zhuo Chen , Chien-Min Kao , Hsin-Hsiung Huang , Lingling An

Positron Emission Tomography (PET) is a powerful molecular imaging tool that plays a crucial role in modern medical diagnostics by visualizing radio-tracer distribution to reveal physiological processes. Accurate organ segmentation from PET…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Yichi Zhang , Le Xue , Wenbo Zhang , Lanlan Li , Yuchen Liu , Chen Jiang , Yuan Cheng , Yuan Qi

Dynamic Positron Emission Tomography (dPET) imaging and Time-Activity Curve (TAC) analyses are essential for understanding and quantifying the biodistribution of radiopharmaceuticals over time and space. Traditional compartmental modeling,…

Machine Learning · Computer Science 2024-06-03 Niloufar Zakariaei , Arman Rahmim , Eldad Haber

Positron Emission Tomography scan images are extensively used in radiotherapy planning, clinical diagnosis, assessment of growth and treatment of a tumor. These all rely on fidelity and speed of detection and delineation algorithm. Despite…

Medical Physics · Physics 2017-10-25 Yeman B. Hagos , Vu H. Minh , Saed Khawaldeh , Usama Pervaiz , Tajwar A. Aleef

Positron emission tomography (PET) is a widely recognized technique for diagnosing neurodegenerative diseases, offering critical functional insights. However, its high costs and radiation exposure hinder its widespread use. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Positron emission tomography (PET) is widely used to assess metabolic activity, but its application is limited by the availability of radiotracers. 18F-labeled fluorodeoxyglucose (18F-FDG) is the most commonly used tracer but shows limited…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Fang Chen , Weifeng Zhang , Xingyu Ai , BingXuan Li , An Li , Qiegen Liu

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Dac Thai Nguyen , Trung Thanh Nguyen , Huu Tien Nguyen , Thanh Trung Nguyen , Huy Hieu Pham , Thanh Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen