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In this study we address the feasibility and main properties of a positron emission tomograph (PET) based on RPCs. The concept, making use of the converter-plate principle, takes advantage of the intrinsic layered structure of RPCs and its…

Instrumentation and Detectors · Physics 2009-11-07 A. Blanco , V. Chepel , R. Ferreira-Marques , P. Fonte , M. I. Lopes , V. Peskov , A. Policarpo

In an ideal medical environment, real-time coagulation monitoring can enable early detection and prompt remediation of risks. However, traditional Thromboelastography (TEG), a widely employed diagnostic modality, can only provide such…

Machine Learning · Computer Science 2026-01-13 Yulu Wang , Ziqian Zeng , Jianjun Wu , Zhifeng Tang

Aggregates of misfolded tau proteins (or just 'tau' for brevity) play a crucial role in the progression of Alzheimer's disease (AD) as they correlate with cell death and accelerated tissue atrophy. Longitudinal positron emission tomography…

Quantitative Methods · Quantitative Biology 2020-12-08 Klaudius Scheufele , Shashank Subramanian , George Biros

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong

Alzheimer's disease (AD) is a major neurodegenerative condition that affects millions around the world. As one of the main biomarkers in the AD diagnosis procedure, brain amyloid positivity is typically identified by positron emission…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Yanxi Chen , Mohammad Farazi , Zhangsihao Yang , Yonghui Fan , Nicholas Ashton , Eric M Reiman , Yi Su , Yalin Wang

Position Emission Tomography (PET) is an advanced clinical diagnostic imaging technique for nuclear medicine. Small animal PET is increasingly uesd for studying the animal model of disease, new drugs and new therapies. A prototype of…

Instrumentation and Detectors · Physics 2019-09-26 Peipei Deng , Lei Zhao , Jiaming Lu , Bowen Li , Ruoshi Dong , Shubin Liu , Qi An

Artificial intelligence (AI)-based methods are showing substantial promise in segmenting oncologic positron emission tomography (PET) images. For clinical translation of these methods, assessing their performance on clinically relevant…

Medical Physics · Physics 2023-04-19 Ziping Liu , Joyce C. Mhlanga , Barry A. Siegel , Abhinav K. Jha

Tumor volume and changes in tumor characteristics over time are important biomarkers for cancer therapy. In this context, FDG-PET/CT scans are routinely used for staging and re-staging of cancer, as the radiolabeled fluorodeoxyglucose is…

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Magnetic resonance imaging (MRI) and positron emission tomography (PET) are increasingly used in multimodal analysis of neurodegenerative disorders. While MRI is broadly utilized in clinical settings, PET is less accessible. Many studies…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Minhui Yu , Mengqi Wu , Ling Yue , Andrea Bozoki , Mingxia Liu

Deep image prior (DIP) has been successfully applied to positron emission tomography (PET) image restoration, enabling represent implicit prior using only convolutional neural network architecture without training dataset, whereas the…

Medical Physics · Physics 2024-04-23 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Keisuke Matsubara , Masanobu Ibaraki

[$^{18}$F]fluorodeoxyglucose (FDG) positron emission tomography (PET) has emerged as a crucial tool in identifying the epileptic focus, especially in cases where magnetic resonance imaging (MRI) diagnosis yields indeterminate results. FDG…

Computer Vision and Pattern Recognition · Computer Science 2024-02-05 Wentao Chen , Jiwei Li , Xichen Xu , Hui Huang , Siyu Yuan , Miao Zhang , Tianming Xu , Jie Luo , Weimin Zhou

We continue studies of the uncertainty quantification problem in emission tomographies such as PET or SPECT when additional multimodal data (e.g., anatomical MRI images) are available. To solve the aforementioned problem we adapt the…

Machine Learning · Statistics 2021-12-03 Fedor Goncharov , Éric Barat , Thomas Dautremer

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

We investigate subset-based optimization methods for positron emission tomography (PET) image reconstruction incorporating a regularizing prior. PET reconstruction methods that use a prior, such as the relative difference prior (RDP), are…

Medical Physics · Physics 2025-06-06 Matthias J. Ehrhardt , Zeljko Kereta , Georg Schramm

We present a fully Bayesian statistical approach to the problem of compartmental modelling in the context of Positron Emission Tomography. We cluster homogeneous region of interest and perform kinetic parameter estimation simultaneously. A…

In this paper, we present our approach to extracting structured information from unstructured Electronic Health Records (EHR) [2] which can be used to, for example, study adverse drug reactions in patients due to chemicals in their…

Computation and Language · Computer Science 2020-01-30 Amogh Kamat Tarcar , Aashis Tiwari , Vineet Naique Dhaimodker , Penjo Rebelo , Rahul Desai , Dattaraj Rao

EasyPET is a new concept of a Positron Emission Tomography (PET) scanner using an innovative acquisition method based on two rotation axes for the movement of detector pairs. Due to its simplicity, it is suitable for education purposes, to…

Medical Physics · Physics 2018-07-03 P. M. M. Correia , J. Menoita , A. L. M. Silva , N. Romanyshyn , J. F. C. A. Veloso

Medical imaging is critical to the diagnosis and treatment of numerous medical problems, including many forms of cancer. Medical imaging reports distill the findings and observations of radiologists, creating an unstructured textual…

Computation and Language · Computer Science 2021-08-23 Kevin Lybarger , Aashka Damani , Martin Gunn , Ozlem Uzuner , Meliha Yetisgen

Tracer kinetic modeling serves a vital role in diagnosis, treatment planning, tracer development and oncology, but burdens practitioners with complex and invasive arterial input function estimation (AIF). We adopt a physics-informed…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Christian Salomonsen , Samuel Kuttner , Michael Kampffmeyer , Robert Jenssen , Kristoffer Wickstrøm , Jong Chul Ye , Elisabeth Wetzer
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