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Positron Annihilation Lifetime Spectroscopy (PALS) allows examining structure of materials in nano and sub-nanometer scale. This technique is based on the lifetime and intensity of ortho-positronium atoms in free volumes of given…

Medical Physics · Physics 2020-01-29 Ewelina Kubicz

Ultrasound simulations used for treatment planning in transcranial ultrasound stimulation(TUS) currently depend on converting computed tomography(CT) images to acoustic properties. Aiming to reduce subject exposure to ionising radiation,…

[18F]FDG-PET/CT is a cornerstone imaging modality for tumor staging and treatment response assessment across many cancer types, yet expert reader shortages necessitate more efficient diagnostic aids. While standalone AI models for automatic…

This work aims at applying the theory of the component-based normalization for the Jagiellonian PET scanner, currently under development at the Jagiellonian University. In any Positron Emission Tomography acquisition, efficiency along a…

Medical Physics · Physics 2024-09-04 Aurélien Coussat , Wojciech Krzemien , Jakub Baran , Szymon Parzych

In this work, we present a fundamental mathematical model for proton transport, tailored to capture the key physical processes underpinning Proton Beam Therapy (PBT). The model provides a robust and computationally efficient framework for…

Medical imaging studies have collected high dimensional imaging data to identify imaging biomarkers for diagnosis, screening, and prognosis, among many others. These imaging data are often represented in the form of a multi-dimensional…

Applications · Statistics 2017-11-09 Michelle F. Miranda , Hongtu Zhu , Joseph G. Ibrahim

Reconstruction of the image in Positron Emission Tomographs (PET) requires the knowledge of the system response kernel which describes the contribution of each pixel (voxel) to each tube of response (TOR). This is especially important in…

Attenuation correction (AC) is necessary for accurate activity quantification in positron emission tomography (PET). Conventional reconstruction methods typically rely on attenuation maps derived from a co-registered computed tomography…

Dynamic positron emission tomography (dPET) is currently a widely used medical imaging technique for the clinical diagnosis, staging and therapy guidance of all kinds of human cancers. Higher temporal imaging resolution for the early stage…

Medical Physics · Physics 2021-12-07 Zixiang Chen , Yaping Wu , Na Zhang , Yu Shen , Hairong Zheng , Dong Liang , Meiyun Wang , Zhanli Hu

Text recognition is a long-standing research problem for document digitalization. Existing approaches are usually built based on CNN for image understanding and RNN for char-level text generation. In addition, another language model is…

Computation and Language · Computer Science 2022-09-07 Minghao Li , Tengchao Lv , Jingye Chen , Lei Cui , Yijuan Lu , Dinei Florencio , Cha Zhang , Zhoujun Li , Furu Wei

Chimeric Antigen Receptor (CAR) T-cell therapy is an immunotherapy that has recently become highly instrumental in the fight against life-threatening diseases. A variety of modeling and computational simulation efforts have addressed…

Quantitative Methods · Quantitative Biology 2021-03-04 Ujwani Nukala , Marisabel Rodriguez Messan , Osman N. Yogurtcu , Xiaofei Wang , Hong Yang

Positron Emission Mammography imaging system (PEMi) is a nuclear medicine diagnosis method dedicated for breast imaging. It provides a better resolution in detection of millimeter-sized breast tumors than whole-body PET. To address the…

Medical Physics · Physics 2015-10-28 Xiao-Yue Gu , Lin Li , Peng-Fei Yin , Ming-Kai Yun , Chai Pei , Xin Fan , Xian-Chao Huang , Xiao-Li Sun , Long Wei

Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to cognitive decline. [$^{18}$F]-Fluorodeoxyglucose positron emission tomography ([$^{18}$F]-FDG PET) is used to monitor brain metabolism, aiding in the diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2024-05-01 Elena Doering , Merle C. Hönig , Tobias Deußer , Gerard N. Bischof , Thilo van Eimeren , Alexander Drzezga , Lotta M. Ellingsen

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Nowadays, our mobility systems are evolving into the era of intelligent vehicles that aim to improve road safety. Due to their vulnerability, pedestrians are the users who will benefit the most from these developments. However, predicting…

Computer Vision and Pattern Recognition · Computer Science 2022-03-18 Lina Achaji , Thierno Barry , Thibault Fouqueray , Julien Moreau , Francois Aioun , Francois Charpillet

List-mode positron emission tomography (PET) image reconstruction is an important tool for PET scanners with many lines-of-response and additional information such as time-of-flight and depth-of-interaction. Deep learning is one possible…

Medical Physics · Physics 2024-02-13 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Takashi Isobe , Yasuomi Ouchi

Proton computed tomography (pCT) aims to facilitate precise dose planning for hadron therapy, a promising and effective method for cancer treatment. Hadron therapy utilizes protons and heavy ions to deliver well focused doses of radiation,…

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of…

Direct reconstruction of positron emission tomography (PET) data using deep neural networks is a growing field of research. Initial results are promising, but often the networks are complex, memory utilization inefficient, produce…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 William Whiteley , Vladimir Panin , Chuanyu Zhou , Jorge Cabello , Deepak Bharkhada , Jens Gregor

Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…