Related papers: SDE-based Monte Carlo dose calculation for proton …
A set of physics models and parameters pertaining to the simulation of proton energy deposition in matter are evaluated in the energy range up to approximately 65 MeV, based on their implementations in the Geant4 toolkit. The analysis…
Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…
Purpose: Dual-energy CT (DECT) has been shown to derive stopping power ratio (SPR) map with higher accuracy than conventional single energy CT (SECT) by obtaining the energy dependence of photon interactions. However, DECT is not as widely…
Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…
Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…
This study develops and validates a patient-specific Monte Carlo (MC) dosimetry framework for propagation-based phase-contrast breast CT (BCT) at the Imaging and Medical Beamline (IMBL), ANSTO Australian Synchrotron, for accurate mean…
The bremsstrahlung spectra produced by electrons impinging on thick targets are simulated using the Geant4 Monte Carlo toolkit. Simulations are validated against experimental data available in literature for a range of energy between 0.5…
Verification of patient specific proton stopping powers obtained in the patient treatment position can be used to reduce the distal margins needed in particle beam planning. Proton radiography can be used as a pre-treatment instrument to…
In this study, the absorbed dose calculation for the cerebral region is refined using the Geant4 software, along with the ROOT and GATE programs. This approach provides a detailed statistical analysis of positron trajectories within a water…
Purpose: To develop a DL-based PBSPT dose prediction workflow with high accuracy and balanced complexity to support on-line adaptive proton therapy clinical decision and subsequent replanning. Methods: PBSPT plans of 103 prostate cancer…
Objective: Proton therapy is a precision-focused cancer treatment where accurate proton beam range monitoring is critical to ensure effective dose delivery. This can be achieved by prompt gamma detection with a Compton camera like the…
Recently, X-ray imaging dose from computed tomography (CT) or cone beam CT (CBCT) scans has become a serious concern. Patient-specific imaging dose calculation has been proposed for the purpose of dose management. While Monte Carlo (MC)…
{\bf Introduction}: To revisit the formulation of the mean chord length in microdosimetry and replace it by the particle mean free path appropriate for modelings in radio-biology. {\bf Methods}: We perform a collision-by-collision following…
Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…
Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…
Dose verification based on proton-induced positron emitters is a promising quality assurance tool and may leverage the strength of artificial intelligence. To move a step closer towards practical application, the sensitivity analysis of two…
Accurate dose calculation on cone beam computed tomography (CBCT) images is essential for modern proton treatment planning workflows, particularly when accounting for inter-fractional anatomical changes in adaptive treatment scenarios.…
We study the energy deposition by light and heavy nuclei in tissue-like media as used for cancer therapy. The depth-dose distributions for protons, $^{3}$He, $^{12}$C, $^{20}$Ne, and $^{58}$Ni nuclei are calculated within a Monte Carlo…
The purpose of this study is to determine whether organ sparing and target coverage can be simultaneously maintained for pencil beam scanning (PBS) proton therapy treatment of thoracic tumors in the presence of motion, stopping power…
Purpose: To introduce and evaluate the use of stable distributions as a means of describing the behavior of charged particle pencil beams in a medium, with specific emphasis on proton beam scanning (PBS). Methods: The proton pencil beams of…