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The COVID-19 pandemic disrupted healthcare systems worldwide, disproportionately impacting individuals with chronic conditions such as cardiovascular disease (CVD). These disruptions -- through delayed care and behavioral changes, affected…

Machine Learning · Computer Science 2025-11-07 Trusting Inekwe , Winnie Mkandawire , Emmanuel Agu , Andres Colubri

Cardiovascular-Kidney-Metabolic (CKM) syndrome represents a growing public health crisis, yet the subclinical heterogeneity of its component systems remains underexplored. Early detection of physiological deviation is critical for…

We study the behavior of a Time-Aware Long Short-Term Memory Autoencoder, a state-of-the-art method, in the context of learning latent representations from irregularly sampled patient data. We identify a key issue in the way such recurrent…

Machine Learning · Computer Science 2019-02-12 Duc Thanh Anh Luong , Varun Chandola

We investigate whether temporal embedding models trained on longitudinal electronic health records can learn clinically meaningful representations without compromising predictive performance, and how architectural choices affect embedding…

Machine Learning · Computer Science 2026-04-17 Aditya Kumar , Mario A. Cypko , Oliver Amft

Acute kidney injury (AKI) in critically ill patients is associated with significant morbidity and mortality. Development of novel methods to identify patients with AKI earlier will allow for testing of novel strategies to prevent or reduce…

Machine Learning · Computer Science 2018-11-12 Yikuan Li , Liang Yao , Chengsheng Mao , Anand Srivastava , Xiaoqian Jiang , Yuan Luo

Advancements in machine learning algorithms have had a beneficial impact on representation learning, classification, and prediction models built using electronic health record (EHR) data. Effort has been put both on increasing models'…

Machine Learning · Computer Science 2021-03-24 Yiwen Meng , William Speier , Michael K. Ong , Corey W. Arnold

Since the World Health Organization declared COVID-19 a pandemic in 2020, the global community has faced ongoing challenges in controlling and mitigating the transmission of the SARS-CoV-2 virus, as well as its evolving subvariants and…

Machine Learning · Computer Science 2023-10-19 Hossein Aboutalebi , Maya Pavlova , Mohammad Javad Shafiee , Adrian Florea , Andrew Hryniowski , Alexander Wong

Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus that affects pediatric patients with significantly greater severity and worse renal outcomes compared to adults. Despite the urgent clinical need, predicting…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Yuewen Huang , Zhitao Ye , Guangnan Feng , Fudan Zheng , Xia Gao , Yutong Lu

Kidney transplantation is the most effective renal replacement therapy for end stage renal disease patients. With the severe shortage of kidney supplies and for the clinical effectiveness of transplantation, patient's life expectancy post…

Methodology · Statistics 2023-10-19 Ge Zhao , Yanyuan Ma , Huazhen Lin , Yi Li

Knee Osteoarthritis (KOA) is a highly prevalent chronic musculoskeletal condition with no currently available treatment. The manifestation of KOA is heterogeneous and prediction of its progression is challenging. Current literature suggests…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

Introduction: For COVID-19 patients accurate prediction of disease severity and mortality risk would greatly improve care delivery and resource allocation. There are many patient-related factors, such as pre-existing comorbidities that…

Purpose: To evaluate the performance of an automated choroid segmentation algorithm in optical coherence tomography (OCT) data using a longitudinal kidney donor and recipient cohort. Methods: We assessed 22 donors and 23 patients requiring…

A kidney transplant can improve the life expectancy and quality of life of patients with end-stage renal failure. Even more patients could be helped with a transplant if the rate of kidneys that are discarded and not transplanted could be…

Predicting future disease progression risk from medical images is challenging due to patient heterogeneity, and subtle or unknown imaging biomarkers. Moreover, deep learning (DL) methods for survival analysis are susceptible to image domain…

Sequential diagnosis prediction on the Electronic Health Record (EHR) has been proven crucial for predictive analytics in the medical domain. EHR data, sequential records of a patient's interactions with healthcare systems, has numerous…

Machine Learning · Computer Science 2021-09-08 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang

The COVID-19 pandemic has had far-reaching implications for global public health. As we continue to grapple with its consequences, it becomes increasingly clear that post-COVID-19 complications are a significant concern. Among these…

We address the problem of predicting when a disease will develop, i.e., medical event time (MET), from a patient's electronic health record (EHR). The MET of non-communicable diseases like diabetes is highly correlated to cumulative health…

Machine Learning · Computer Science 2023-06-01 Takayuki Katsuki , Kohei Miyaguchi , Akira Koseki , Toshiya Iwamori , Ryosuke Yanagiya , Atsushi Suzuki

Background: Cirrhosis is a progressive liver disease with high mortality and frequent complications, notably acute kidney injury (AKI), which occurs in up to 50% of hospitalized patients and worsens outcomes. AKI stems from complex…

Machine Learning · Computer Science 2025-08-15 Li Sun , Shuheng Chen , Junyi Fan , Yong Si , Minoo Ahmadi , Elham Pishgar , Kamiar Alaei , Maryam Pishgar

Background: Acute kidney injury (AKI) is a common complication in hospitalized patients and a common cause for chronic kidney disease (CKD) and increased hospital cost and mortality. By timely detection of AKI and AKI progression, effective…

Background: Acute kidney injury (AKI), the decline of kidney excretory function, occurs in up to 18% of hospitalized admissions. Progression of AKI may lead to irreversible kidney damage. Methods: This retrospective cohort study includes…