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Related papers: Chronic Kidney Disease Prognosis Prediction Using …

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Chronic Kidney Disease (CKD) affects millions of people worldwide, yet its early detection remains challenging, especially in outpatient settings where laboratory-based renal biomarkers are often unavailable. In this work, we investigate…

Repeated longitudinal measurements are commonly used to model long-term disease progression, and timing and number of assessments per patient may vary, leading to irregularly spaced and sparse data. Longitudinal trajectories may exhibit…

The incidence of Acute Kidney Injury (AKI) commonly happens in the Intensive Care Unit (ICU) patients, especially in the adults, which is an independent risk factor affecting short-term and long-term mortality. Though researchers in recent…

Machine Learning · Computer Science 2020-05-28 Yu Wang , JunPeng Bao , JianQiang Du , YongFeng Li

Patients with acute kidney injury (AKI) are at high risk of developing chronic kidney disease (CKD), but identifying those at greatest risk remains challenging. We used electronic health record (EHR) data to dynamically track AKI patients'…

Computation and Language · Computer Science 2026-04-13 Yilu Fang , Jordan G. Nestor , Casey N. Ta , Jerard Z. Kneifati-Hayek , Chunhua Weng

Accurate disease trajectory prediction is critical for early intervention, resource allocation, and improving long-term outcomes. While electronic health records (EHRs) provide a rich longitudinal view of patient health in clinical…

Machine Learning · Computer Science 2026-05-15 Yunying Zhu , Andrew R Weckstein , Kueiyu Joshua Lin , Jie Yang

Long-horizon clinical simulation -- predicting how a patient's physiology evolves over years under specified interventions -- is central to chronic-disease care, yet existing electronic health record (EHR) models are predominantly…

Machine Learning · Computer Science 2026-05-22 Jiangyuan Wang , Xuyong Chen , Junwei He , Xu Xu , Shasha Xie , Fuman Han

Areas where Artificial Intelligence (AI) & related fields are finding their applications are increasing day by day, moving from core areas of computer science they are finding their applications in various other domains.In recent times…

Machine Learning · Computer Science 2016-07-19 Sahil Sharma , Vinod Sharma , Atul Sharma

Progression to dialysis or end-stage renal disease is a rare but clinically important outcome. Clinicians need evidence on how medication exposures influence downstream risk. We constructed a fixed-window EHR cohort (90-day observation,…

Machine Learning · Computer Science 2026-04-28 Kalyani P. Pande , Evan Yang , Bryan Zhu , Sandeep K. Mallipattu , Alisa Yurovsky , Tengfei Ma

A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE…

Machine Learning · Statistics 2017-02-08 David Ledbetter , Long Ho , Kevin V Lemley

Chronic kidney disease (CKD) is a global health challenge characterized by progressive kidney function decline, often culminating in end-stage kidney disease (ESKD) and increased mortality. To address the limitations such as the extended…

Methodology · Statistics 2025-04-11 Tuo Wang , Yu Du

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Acute kidney injury (AKI) is a common clinical syndrome characterized by a sudden episode of kidney failure or kidney damage within a few hours or a few days. Accurate early prediction of AKI for patients in ICU who are more likely than…

Computation and Language · Computer Science 2022-05-10 Chengsheng Mao , Liang Yao , Yuan Luo

Question: Can an encoder-decoder architecture pretrained on a large dataset of longitudinal electronic health records improves patient outcome predictions? Findings: In this prognostic study of 6.8 million patients, our denoising…

Artificial Intelligence · Computer Science 2022-12-26 Zhichao Yang , Weisong Liu , Dan Berlowitz , Hong Yu

Chronic disease progression is emerging as an important area of investment for healthcare providers. As the quantity and richness of available clinical data continue to increase along with advances in machine learning, there is great…

Machine Learning · Computer Science 2019-11-14 Sunil Mallya , Marc Overhage , Sravan Bodapati , Navneet Srivastava , Sahika Genc

Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness. Early indication and detection of diseases,…

Accurate early prediction of Acute Kidney Injury (AKI) is critical for timely clinical intervention. However, existing deep learning models struggle with irregularly sampled data and suffer from the opaque "black-box" nature of sequential…

Machine Learning · Computer Science 2026-04-23 Weizhi Nie , Haolin Chen

Electronic Health Records (EHR)-based disease prediction models have demonstrated significant clinical value in promoting precision medicine and enabling early intervention. However, existing large language models face two major challenges:…

Computation and Language · Computer Science 2025-06-19 Junke Wang , Hongshun Ling , Li Zhang , Longqian Zhang , Fang Wang , Yuan Gao , Zhi Li

Deep learning (DL) based predictive models from electronic health records (EHR) deliver impressive performance in many clinical tasks. Large training cohorts, however, are often required to achieve high accuracy, hindering the adoption of…

Computation and Language · Computer Science 2020-05-27 Laila Rasmy , Yang Xiang , Ziqian Xie , Cui Tao , Degui Zhi

Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…

Machine Learning · Statistics 2016-08-17 Joseph Futoma , Mark Sendak , C. Blake Cameron , Katherine Heller

Early detection of chronic kidney disease (CKD) is essential for preventing progression to end-stage renal disease. However, existing screening tools - primarily developed using populations from high-income countries - often underperform in…