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Chronic diseases such as diabetes are the leading causes of morbidity and mortality worldwide. Numerous research studies have been attempted with various deep learning models in diagnosis. However, most previous studies had certain…

Acute kidney injury (AKI) is a serious clinical condition that affects up to 20% of hospitalised patients. AKI is associated with short term unplanned hospital readmission and post-discharge mortality risk. Patient risk and healthcare…

Machine Learning · Computer Science 2024-10-24 Flavio S. Correa da Silva , Simon Sawhney

Paediatric kidney disease varies widely in its presentation and progression, which calls for continuous monitoring of renal function. Using electronic health records collected between 2019 and 2025 at Great Ormond Street Hospital, a leading…

Machine Learning · Computer Science 2025-11-18 Ana Durica , John Booth , Ivana Drobnjak

This article introduces Transformer Quantile Regression Neural Networks (TQRNNs), a novel data-driven solution for real-time machine failure prediction in manufacturing contexts. Our objective is to develop an advanced predictive…

Signal Processing · Electrical Eng. & Systems 2024-11-25 David J Poland , Lemuel Puglisi , Daniele Ravi

Cox-nnet is a neural-network based prognosis prediction method, originally applied to genomics data. Here we propose the version 2 of Cox-nnet, with significant improvement on efficiency and interpretability, making it suitable to predict…

Quantitative Methods · Quantitative Biology 2020-09-10 Di Wang , Kevin He , Lana X Garmire

Diabetes is a chronic disease characterised by a high risk of developing diabetic nephropathy, which, in turn, is the leading cause of end-stage chronic kidney disease. The early identification of individuals at heightened risk of such…

Quantitative Methods · Quantitative Biology 2024-09-24 Davide Dei Cas , Barbara Di Camillo , Gian Paolo Fadini , Giovanni Sparacino , Enrico Longato

Discovering gene-disease associations is crucial for understanding disease mechanisms, yet identifying these associations remains challenging due to the time and cost of biological experiments. Computational methods are increasingly vital…

Artificial Intelligence · Computer Science 2025-01-15 Wentao Cui , Shoubo Li , Chen Fang , Qingqing Long , Chengrui Wang , Xuezhi Wang , Yuanchun Zhou

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

25% of people who received a liver transplant will go on to develop diabetes within the next 5 years. These thousands of individuals are at 2-fold higher risk of cardiovascular events, graft loss, infections, as well as lower long-term…

Machine Learning · Computer Science 2019-06-06 Angeline Yasodhara , Mamatha Bhat , Anna Goldenberg

Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications that affect patient prognosis.…

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

Machine Learning · Computer Science 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq

The relationship between acute kidney injury (AKI) prediction and nephrotoxic drugs, or drugs that adversely affect kidney function, is one that has yet to be explored in the critical care setting. One contributing factor to this gap in…

Machine Learning · Computer Science 2024-01-10 Gabriel D. M. Manalu , Mulomba Mukendi Christian , Songhee You , Hyebong Choi

Multi-stage disease histories derived from longitudinal data are becoming increasingly available as registry data and biobanks expand. Multi-state models are suitable to investigate transitions between different disease stages in presence…

Accurate prediction of knee osteoarthritis (KOA) progression from structural MRI has a potential to enhance disease understanding and support clinical trials. Prior art focused on manually designed imaging biomarkers, which may not fully…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

The rapid spread of COVID-19 cases in recent months has strained hospital resources, making rapid and accurate triage of patients presenting to emergency departments a necessity. Machine learning techniques using clinical data such as chest…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Anuroop Sriram , Matthew Muckley , Koustuv Sinha , Farah Shamout , Joelle Pineau , Krzysztof J. Geras , Lea Azour , Yindalon Aphinyanaphongs , Nafissa Yakubova , William Moore

Patients with chronic obstructive pulmonary disease (COPD) have an increased risk of hospitalizations, strongly associated with decreased survival, yet predicting the timing of these events remains challenging and has received limited…

We introduce a novel contextual embedding model med-gte-hybrid that was derived from the gte-large sentence transformer to extract information from unstructured clinical narratives. Our model tuning strategy for med-gte-hybrid combines…

Computation and Language · Computer Science 2025-12-02 Aditya Kumar , Simon Rauch , Mario Cypko , Oliver Amft

Assessment of circulating CD4 count change over time in HIV-infected subjects on antiretroviral therapy (ART) is a central component of disease monitoring. The increasing number of HIV-infected subjects starting therapy and the limited…

Forecasting healthcare time series data is vital for early detection of adverse outcomes and patient monitoring. However, it can be challenging in practice due to variable medication administration and unique pharmacokinetic (PK) properties…

Machine Learning · Computer Science 2025-12-17 Willa Potosnak , Cristian Challu , Kin G. Olivares , Keith A. Dufendach , Artur Dubrawski

Chronic pain is a global health challenge affecting millions of individuals, making it essential for physicians to have reliable and objective methods to measure the functional impact of clinical treatments. Traditionally used methods, like…

Machine Learning · Computer Science 2026-03-23 Yuanheng Mao , Lillian Yang , Stephen Yang , Ethan Shao , Zihan Li
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