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The purpose of this study is to enable in-vivo three-dimensional (3-D) ultrasound localization microscopy (ULM) of posterior ocular microvasculature using a 256-channel system and a 1024-element matrix array, and to overcome limitations of…

Nonlinear optical microscopy allows rapid high-resolution microscopy with image contrast generated from intrinsic properties of the sample. Established modalities such as multiphoton excited fluorescence and second/third-harmonic generation…

Multiplexed planar printings, made of single or few layer micro and nano optical platforms, are essential for high capacity display, information storage and encryption. Although having been developed rapidly, the demonstrated channels are…

Optics · Physics 2022-06-17 Yunxuan Wei , Tie Hu , Xing Feng , Ming Zhao , Zhenyu Yang

Compressive spectral imaging enables to reconstruct the entire three-dimensional (3D) spectral cube from a few multiplexed images. Here, we develop a novel compressive spectral imaging technique using diffractive lenses. Our technique uses…

Image and Video Processing · Electrical Eng. & Systems 2019-09-24 Oğuzhan Fatih Kar , Figen S. Oktem

The microlens is a key enabling technology in optoelectronics, permitting light to be efficiently coupled to and from devices such as image sensors and light-emitting diodes. Their ubiquitous nature motivates the development of new…

Materials Science · Physics 2015-05-07 Yaping Dan , Kaixiang Chen , Kenneth B. Crozier

By switching fluorophores on and off in either a deterministic or a stochastic manner, superresolution microscopy has enabled the imaging of biological structures at resolutions well beyond the diffraction limit. Superresolution optical…

Three-dimensional elements, with refractive index distribution structured at sub-wavelength scale, provide an expansive optical design space that can be harnessed for demonstrating multi-functional free-space optical devices. Here we…

Integration of metasurfaces with guided mode sources like waveguides have opened new frontiers for on-chip optical integration. However, the state-of-the-art in the field has targeted applications where long focal distances over thousands…

Optics · Physics 2024-03-05 Hrishikesh Iyer , Yurii Vlasov

Three-dimensional (3D) imaging of thin, extended specimens at nanometer resolution is critical for applications in biology, materials science, advanced synthesis, and manufacturing. One route to 3D imaging is tomography, which requires a…

Instrumentation and Detectors · Physics 2023-10-23 Deepan Balakrishnan , See Wee Chee , Zhaslan Baraissov , Michel Bosman , Utkur Mirsaidov , N. Duane Loh

Replacing electrons with photons is a compelling route towards light-speed, highly parallel, and low-power artificial intelligence computing. Recently, all-optical diffractive neural deep neural networks have been demonstrated. However, the…

Signal Processing · Electrical Eng. & Systems 2021-07-19 Xuhao Luo , Yueqiang Hu , Xin Li , Xiangnian Ou , Jiajie Lai , Na Liu , Huigao Duan

High-resolution lithographic techniques are often limited by low volumetric throughput, since there is no universal and scalable manufacturing process that can produce 3D metasurfaces. In this work, we demonstrate a high-speed holographic…

Digital holographic microscopy is an emerging potentially low-cost alternative to conventional light microscopy for micro-object imaging on earth, underwater and in space. Immediate access to micron-scale objects however requires a…

Optics · Physics 2019-04-10 Stephan Amann , Max von Witzleben , and Stefan Breuer

Multi-plane light converters (MPLCs) are an emerging 3D beam shaping technology capable of deterministically mapping a basis of input spatial light modes to a new basis of output modes. The ability to perform such spatial reformatting…

Optics · Physics 2026-02-10 Unė G. Būtaitė , Martynas Beresna , David B. Phillips

Coherent diffractive imaging is unique as the only route for achieving diffraction-limited spatial resolution in the extreme ultraviolet and X-ray regions, limited only by the wavelength of the light. Recently, advances in coherent short…

Coherent optics has profoundly impacted diverse applications ranging from communications, LiDAR to quantum computations. However, building coherent systems in integrated photonics previously came at great expense in hardware integration and…

Arbitrary manipulation of light across multiple physical dimensions is essential for harnessing its parallelism in fundamental research and advanced applications, such as optical interconnects, computing, imaging, sensing, and quantum…

The row-column addressed array is an emerging probe for ultrafast 3-D ultrasound imaging. It achieves this with far fewer independent electronic channels and a wider field of view than traditional 2-D matrix arrays, of the same channel…

Super-resolution imaging methods that combine interferometric (z) analysis with single-molecule localization microscopy (iSMLM) have achieved ultra-high 3D precision and contributed to the elucidation of important biological…

Optics · Physics 2025-02-20 Wei Wang , Zengxin Huang , Yilin Wang , Hangfeng Li , Pakorn Kanchanawong

High-contrast imaging relies on advanced coronagraphs and adaptive optics (AO) to attenuate the starlight. However, residual aberrations, especially non-common path aberrations between the AO channel and the coronagraph channel, limit the…

Instrumentation and Methods for Astrophysics · Physics 2025-11-11 Axel Potier , Raphaël Galicher , Pierre Baudoz , Johan Mazoyer , Zahed Wahhaj , Ruben Tandon , Jonas G. Kühn , Laura Perez , Gael Chauvin

Depth imaging is vital for many emerging technologies with applications in augmented reality, robotics, gesture detection, and facial recognition. These applications, however, demand compact and low-power systems beyond the capabilities of…

Optics · Physics 2019-10-29 Shane Colburn , Arka Majumdar