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The COVID-19 pandemic has had worldwide devastating effects on human lives, highlighting the need for tools to predict its development. Dynamics of such public-health threats can often be efficiently analysed through simple models that help…

Populations and Evolution · Quantitative Biology 2021-06-04 Pedro L. de Andres , Lucia de Andres-Bragado , Linard D. Hoessly

Metapopulation epidemic models help capture the spatial dimension of infectious disease spread by dividing heterogeneous populations into separate but interconnected communities, represented by nodes in a network. In the event of an…

Populations and Evolution · Quantitative Biology 2025-02-21 Henrik Zunker , Philipp Dönges , Patrick Lenz , Seba Contreras , Martin J. Kühn

This paper proposes an approach to mitigate epidemic spread in a population of strategic agents by encouraging safer behaviors through carefully designed rewards. These rewards, which adapt to the evolving state of the epidemic, are…

Systems and Control · Electrical Eng. & Systems 2024-12-31 Shinkyu Park , Jair Certorio , Nuno C. Martins , Richard J. La

In this work, we aim to formalize a novel scientific machine learning framework to reconstruct the hidden dynamics of the transmission rate, whose inaccurate extrapolation can significantly impair the quality of the epidemic forecasts, by…

Quantitative Methods · Quantitative Biology 2024-10-16 Giovanni Ziarelli , Stefano Pagani , Nicola Parolini , Francesco Regazzoni , Marco Verani

This study presents a neural network-enhanced approach to modeling disease spread dynamics over time and space. Neural networks are used to estimate time-varying parameters, with two calibration methods explored: Approximate Bayesian…

Quantitative Methods · Quantitative Biology 2024-10-29 Randy L. Caga-anan

For the description of a pandemic mathematical models could be interesting. Both for physicians and politicians as a base for decisions to treat the disease. The responsible estimation of parameters is a main issue of mathematical pandemic…

Populations and Evolution · Quantitative Biology 2020-04-15 Günter Bärwolff

We propose a mathematical spatiotemporal epidemic SICA model with a control strategy. The spatial behavior is modeled by adding a diffusion term with the Laplace operator, which is justified and interpreted both mathematically and…

Optimization and Control · Mathematics 2022-07-12 Houssine Zine , Abderrahim El Adraoui , Delfim F. M. Torres

The outbreak of COVID-19 has highlighted the intricate interplay between public health and economic stability on a global scale. This study proposes a novel reinforcement learning framework designed to optimize health and economic outcomes…

Machine Learning · Computer Science 2024-05-01 Maeghal Jain , Ziya Uddin , Wubshet Ibrahim

This work investigates the benefits of implementing a systematic approach to social isolation policies during epidemics. We develop a mixed integer data-driven model predictive control (MPC) scheme based on an SIHRD model which is…

Populations and Evolution · Quantitative Biology 2025-07-04 S. Z. Sayed Hassen , A. Aboudonia , J. Lygeros

In the framework of homogeneous susceptible-infected-recovered (SIR) models, we use a control theory approach to identify optimal pandemic mitigation strategies. We derive rather general conditions for reaching herd immunity while…

Populations and Evolution · Quantitative Biology 2021-07-05 Prakhar Godara , Stephan Herminghaus , Knut M. Heidemann

We calculate epidemic thresholds and investigate the dynamics of a disease in a networked metapopulation model. To study the specific role of mobility levels and network geometry, we utilize the SIR-Network model and consider a range of…

Physics and Society · Physics 2023-08-07 Haridas K. Das , Lucas M. Stolerman

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

Optimization and Control · Mathematics 2023-03-16 Tom Britton , Lasse Leskelä

Epidemiologists model the dynamics of epidemics in order to propose control strategies based on pharmaceutical and non-pharmaceutical interventions (contact limitation, lock down, vaccination, etc). Hand-designing such strategies is not…

In this study, we present an epidemic-controlled SIRD model with two types of control strategies: mask wear and screening. The aim of this study is to minimize the number of deceased keeping a minimal cost of mask advertising and screening.…

Populations and Evolution · Quantitative Biology 2021-09-06 Amira Bouhali , Walid Ben Aribi , Slimane Ben Miled , Amira Kebir

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

We present a mathematical model to study the transmission dynamics of soil-transmitted helminth (STH) infections and to assess the impact of community-based water, sanitation, and hygiene (WASH) program interventions. STH infections are a…

Populations and Evolution · Quantitative Biology 2025-08-06 Gonzalo Maximiliano Lopez , Juan Pablo Aparicio

We present a mathematical analysis of the early detection of Ebola virus. The propagation of the virus is analysed by using a Susceptible, Infected, Recovered (SIR) model. In order to provide useful predictions about the potential…

Populations and Evolution · Quantitative Biology 2016-05-24 Amira Rachah , Delfim F. M. Torres

In this paper we present a model describing Susceptible-Infected-Susceptible (SIS) type epidemics spreading on a dynamic contact network with random link activation and deletion where link ac- tivation can be locally constrained. We use and…

Dynamical Systems · Mathematics 2015-05-30 Michael Taylor , Timothy J. Taylor , Istvan Z. Kiss

Accurate epidemic forecasting is crucial for effective disease control and prevention. Traditional compartmental models often struggle to estimate temporally and spatially varying epidemiological parameters, while deep learning models…

Machine Learning · Computer Science 2025-04-08 Shuai Han , Lukas Stelz , Thomas R. Sokolowski , Kai Zhou , Horst Stöcker
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