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The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

In this paper, we formulate cyber risk management and mitigation as a stochastic optimal control problem under a stochastic Susceptible-Infected-Susceptible (SIS) epidemic model. To capture the dynamics and interplay of management and…

Optimization and Control · Mathematics 2026-01-29 Shize Na , Zhuo Jin , Ran Xu , Hailiang Yang

The dramatic outbreak of the coronavirus disease 2019 (COVID-19) pandemics and its ongoing progression boosted the scientific community's interest in epidemic modeling and forecasting. The SIR (Susceptible-Infected-Removed) model is a…

Populations and Evolution · Quantitative Biology 2021-02-24 Dimiter Prodanov

Dynamics on networks is considered from the perspective of Markov stochastic processes. We partially describe the state of the system through network motifs and infer any missing data using the available information. This versatile approach…

In this paper we introduce an approach to the management of infectious disease diffusion through the formulation of a controlled compartmental SVIR (Susceptible-Vaccinated-Infected-Recovered) model. We consider a cost functional…

Optimization and Control · Mathematics 2023-11-28 Alessandro Ramponiand M. Elisabetta Tessitore

Various non pharmaceutical interventions have been settled to minimise the burden of the COVID-19 outbreak. We build a framework to analyse the dynamics of non pharmaceutical interventions, to distinguish between mitigations measures…

Populations and Evolution · Quantitative Biology 2023-01-23 Laurent Evain , Jean-Jacques Loeb

The SIR model is the cornerstone model for mathematical epidemiology, explaining key epidemic features such as the second-order transition between disease-free and epidemic states, the initial exponential growth of outbreaks or the…

Populations and Evolution · Quantitative Biology 2026-03-20 Santiago Lamata-Otín , Alex Arenas , Jesús Gómez-Gardeñes , David Soriano-Paños

Infectious diseases are a threat for human health with tremendous impact on our society at large. The recent COVID-19 pandemic, caused by the SARS-CoV-2, is the latest example of a highly infectious disease ravaging the world, since late…

Populations and Evolution · Quantitative Biology 2021-09-17 Giacomo Cacciapaglia , Corentin Cot , Michele Della Morte , Stefan Hohenegger , Francesco Sannino , Shahram Vatani

Two factors that are often ignored but could play a crucial role in the progression of an infectious disease are the distributions of inherent susceptibility ($\sigma_{inh}$) and external infectivity ($\iota_{ext}$), in a given population.…

Populations and Evolution · Quantitative Biology 2021-01-01 Saumyak Mukherjee , Sayantan Mondal , Biman Bagchi

Epidemic outbreaks are an important healthcare challenge, especially in developing countries where they represent one of the major causes of mortality. Approaches that can rapidly target subpopulations for surveillance and control are…

Social and Information Networks · Computer Science 2018-07-04 Stefania Rubrichi , Zbigniew Smoreda , Mirco Musolesi

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

We design and analyze a multi-level game-theoretic model of hierarchical policy interventions for epidemic control, such as those in response to the COVID-19 pandemic. Our model captures the potentially mismatched priorities among a…

Computer Science and Game Theory · Computer Science 2022-08-05 Feiran Jia , Aditya Mate , Zun Li , Shahin Jabbari , Mithun Chakraborty , Milind Tambe , Michael Wellman , Yevgeniy Vorobeychik

In this paper we make the first steps to bridge the gap between classic control theory and modern, network-based epidemic models. In particular, we apply nonlinear model predictive control (NMPC) to a pairwise ODE model which we use to…

Classical Analysis and ODEs · Mathematics 2014-02-11 Fanni Sélley , Ádám Besenyei , Istvan Z. Kiss , Péter L. Simon

In this work, we develop a spatial SEIAR-type epidemic model considering a quarantined population (denoted as Q), which we call the SQEIAR model. The dynamics of the SQEIAR model are described by six Partial Differential Equations (PDEs)…

Dynamical Systems · Mathematics 2025-01-27 Elghandouri Mohammed , Ezzinbi Khalil , Youness Mezzan

One of the popular dynamics on complex networks is the epidemic spreading. An epidemic model describes how infections spread throughout a network. Among the compartmental models used to describe epidemics, the…

Physics and Society · Physics 2011-07-14 Faryad Darabi Sahneh , Caterina Scoglio

The ever-changing world of disease study heavily relies on mathematical models. They are key in finding and controlling infectious diseases. We aim to explore these mathematical tools used for studying disease spread in biology. The SEIR…

History and Overview · Mathematics 2025-01-03 Pabel Shahrear , Md. Shahedul Islam , Md. Abu Bakkar , Anika Bushra , Ismail Hossain

We present a new mathematical model to explicitly capture the effects that the three restriction measures: the lockdown date and duration, social distancing and masks, and, schools and border closing, have in controlling the spread of…

Populations and Evolution · Quantitative Biology 2020-08-25 Liam Dowling Jones , Malik Magdon-Ismail , Laura Mersini-Houghton , Steven Meshnick

During an epidemic outbreak, individuals often modify their behavior in response to global prevalence cues, using spatially mediated adaptations such as reduced mobility or transmission range. In this work, we investigate the impact of…

Physics and Society · Physics 2026-03-18 Akhil Panicker , Sasidevan V

A key problem in modelling the evolution dynamics of infectious diseases is the mathematical representation of the mechanism of transmission of the contagion. Models with a finite number of subpopulations can be described via systems of…

Optimization and Control · Mathematics 2017-03-09 Sebastian Anita , Vincenzo Capasso

We extend the classical Susceptible-Infected-Recovered (SIR) model to a network-based framework where the degree distribution of nodes follows a Poisson distribution. This extension incorporates an additional parameter representing the mean…

Populations and Evolution · Quantitative Biology 2025-01-03 Josephine K. Wairimu , Andrew Gothard , Grzegorz A. Rempala