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We propose a network behavioral-feedback Susceptible-Infected-Recovered (SIR) epidemic model in which the interaction matrix describing the infection rates across subpopulations depends in feedback on the current epidemic state. This model…

Dynamical Systems · Mathematics 2025-07-08 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani

We have devised a data-driven framework for uncovering hidden control strategies used by an evolutionary system described by an evolutionary probability distribution. This innovative framework enables deciphering of the concealed mechanisms…

Populations and Evolution · Quantitative Biology 2023-09-28 Nourddine Azzaoui , Tomoko Matsui , Daisuke Murakami

Epidemic threshold is one of the most important features of the epidemic dynamics. Through a lot of numerical simulations in classic Susceptible-Infected-Recovered (SIR) and Susceptible-Infected-Susceptible (SIS) models on various types of…

Physics and Society · Physics 2014-10-16 Panpan Shu , Wei Wang , Ming Tang , Younghae Do

Controlling an epidemiological model is often performed using optimal control theory techniques for which the solution depends on the equations of the control system, objective functional and possible state and/or control constraints. In…

Optimization and Control · Mathematics 2021-11-25 Loïc Michel , Cristiana J. Silva , Delfim F. M. Torres

Global strategies to contain a pandemic, such as social distancing and protective measures, are designed to reduce the overall transmission rate between individuals. Despite such measures, essential institutions, including hospitals,…

Populations and Evolution · Quantitative Biology 2022-09-07 Roberto Morán-Tovar , Henning Gruell , Florian Klein , Michael Lässig

In this work, we integrate the predictive capabilities of compartmental disease dynamics models with machine learning ability to analyze complex, high-dimensional data and uncover patterns that conventional models may overlook.…

Numerical Analysis · Mathematics 2025-05-28 Muhammad Awais , Abu Safyan Ali , Giacomo Dimarco , Federica Ferrarese , Lorenzo Pareschi

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

Optimization and Control · Mathematics 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

In this paper we propose a macro-dynamic age-structured set-up for the analysis of epidemics/economic dynamics in continuous time. The resulting optimal control problem is reformulated in an infinite dimensional Hilbert space framework…

Theoretical Economics · Economics 2020-08-18 Giorgio Fabbri , Fausto Gozzi , Giovanni Zanco

The SARS-CoV-2 infectious outbreak has rapidly spread across the globe and precipitated varying policies to effectuate physical distancing to ameliorate its impact. In this study, we propose a new hybrid machine learning model, SIRNet, for…

Populations and Evolution · Quantitative Biology 2020-04-23 Nicholas Soures , David Chambers , Zachariah Carmichael , Anurag Daram , Dimpy P. Shah , Kal Clark , Lloyd Potter , Dhireesha Kudithipudi

We investigate the use of hybrid techniques in complex processes of infectious diseases. Since predictive disease models in biomedicine require a multiscale approach for understanding the molecule-cell-tissue-organ-body interactions,…

Logic in Computer Science · Computer Science 2012-08-21 Pietro Liò , Emanuela Merelli , Nicola Paoletti

We study a resource allocation problem for containing an infectious disease in a metapopulation subject to resource uncertainty. We propose a two-stage model where the policy maker seeks to allocate resources in both stages where the second…

Optimization and Control · Mathematics 2020-06-03 Ceyda Yaba Best , Amin Khademi , Burak Eksioglu

We study the problem of containing epidemic spreading processes in temporal networks. We specifically focus on the problem of finding a resource allocation to suppress epidemic infection, provided that an empirical time-series data of…

Social and Information Networks · Computer Science 2019-04-16 Masaki Ogura , Junichi Harada

The last decade saw the advent of increasingly realistic epidemic models that leverage on the availability of highly detailed census and human mobility data. Data-driven models aim at a granularity down to the level of households or single…

Populations and Evolution · Quantitative Biology 2011-08-10 Nicola Perra , Duygu Balcan , Bruno Gonçalves , Alessandro Vespignani

The metapopulation network model is effectively used to study the spatial spread of epidemics with individuals mobility. Considering the time-varying nature of individual activity and the preferences for attractive destinations in…

Physics and Society · Physics 2023-11-27 Lang Zeng , Ming Tang , Ying Liu , Seung Yeop Yang , Younghae Do

We propose a versatile model with a flexible choice of control for an early-pandemic outbreak prevention when vaccine/drug is not yet available. At that stage, control is often limited to non-medical interventions like social distancing and…

Optimization and Control · Mathematics 2024-06-14 Alexandra Smirnova , Xiaojing Ye

This contribution aims to shed light on mathematical epidemic dynamics modelling from the viewpoint of analytical mechanics. To set the stage, it recasts the basic SIR model of mathematical epidemic dynamics in an analytical mechanics…

Dynamical Systems · Mathematics 2020-12-16 Paul Steinmann

Self-adaptive dynamics occurs in many physical systems such as socio-economics, neuroscience, or biophysics. We formalize a self-adaptive modeling approach, where adaptation takes place within a set of strategies based on the history of the…

Adaptation and Self-Organizing Systems · Physics 2022-04-01 Konstantin Clauß , Christian Kuehn

We study first order necessary conditions for an optimal control problem of a Susceptible-Infected-Recovered (SIR) model with limitations on the duration of the quarantine. The control is done by means of the reproduction number, i.e., the…

A plethora of prediction models of SARS-CoV-2 pandemic were proposed in the past. Prediction performances not only depend on the structure and features of the model, but also on its parametrization. Official databases are often biased due…

Populations and Evolution · Quantitative Biology 2021-09-27 Yuri Kheifetz , Holger Kirsten , Markus Scholz

Recent wide spreading of Ransomware has created new challenges for cybersecurity over large-scale networks. The densely connected networks can exacerbate the spreading and makes the containment and control of the malware more challenging.…

Systems and Control · Computer Science 2018-10-12 Vladislav Taynitskiy , Elena Gubar , Quanyan Zhu
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