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In large-scale spatial surveys, such as the forthcoming ESA Euclid mission, images may be undersampled due to the optical sensors sizes. Therefore, one may consider using a super-resolution (SR) method to recover aliased frequencies, prior…

Computer Vision and Pattern Recognition · Computer Science 2014-10-30 Fred Maurice Ngolè Mboula , Jean-Luc Starck , Samuel Ronayette , Koryo Okumura , Jérôme Amiaux

Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

Biomolecules · Quantitative Biology 2015-04-15 Mark Leake

Fluorescence lifetime imaging microscopy (FLIM) provides detailed information about molecular interactions and biological processes. A major bottleneck for FLIM is image resolution at high acquisition speeds, due to the engineering and…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Valentin Kapitány , Areeba Fatima , Vytautas Zickus , Jamie Whitelaw , Ewan McGhee , Robert Insall , Laura Machesky , Daniele Faccio

Single molecule localization microscopy (SMLM) techniques enable imaging biological samples well beyond the diffraction limit of light, but they vary significantly in their spatial and temporal resolutions. High-order statistical analysis…

Biological Physics · Physics 2016-03-15 Shachar Schidorsky , Xiyu Yi , Yair Razvag , Yonatan Golan , Shimon Weiss , Eilon Sherman

Selective plane illumination microscopy (SPIM), also known as light sheet fluorescence microscopy, provides high specificity through fluorescence labeling. However, it lacks complementary structural information from the surrounding context,…

Optics · Physics 2024-12-19 Rui Ma , Olga Lyraki , Daniel Wehner , Jochen Guck

The resolution of optical imaging is classically limited by the width of the point-spread function, which in turn is determined by the Rayleigh length. Recently, spatial-mode demultiplexing (SPADE) has been proposed as a method to achieve…

Quantum Physics · Physics 2025-02-26 Giuseppe Buonaiuto , Cosmo Lupo

Fluorescence microscopy has enabled a dramatic development in modern biology. Due to its inherently weak signal, fluorescence microscopy is not only much noisier than photography, but also presented with Poisson-Gaussian noise where Poisson…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Yide Zhang , Yinhao Zhu , Evan Nichols , Qingfei Wang , Siyuan Zhang , Cody Smith , Scott Howard

In fluorescence microscopy, spectral unmixing aims to recover individual fluorophore concentrations from spectral images that capture mixed fluorophore emissions. Since classical methods operate pixel-wise and rely on least-squares fitting,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Federico Carrara , Talley Lambert , Mehdi Seifi , Florian Jug

When adapting Simultaneous Mapping and Localization (SLAM) to real-world applications, such as autonomous vehicles, drones, and augmented reality devices, its memory footprint and computing cost are the two main factors limiting the…

Robotics · Computer Science 2022-11-04 Yeonsoo Park , Soohyun Bae

While Vision Transformers (ViT) have demonstrated remarkable performance across diverse tasks, their computational demands are substantial, scaling quadratically with the number of processed tokens. Compact attention representations,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Oded Schlesinger , Amirhossein Farzam , J. Matias Di Martino , Guillermo Sapiro

Super-resolution techniques overcome the diffraction-limit and get very high resolutions. A category of these techniques, e.g., STED achieves this by creating an illumination spot smaller than the Airy Disk. As a result, points are…

Image and Video Processing · Electrical Eng. & Systems 2019-11-20 Yaohua Xie

High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

Image and Video Processing · Electrical Eng. & Systems 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

Nanoparticles (NPs) have proven their applicability in biosensing, drug delivery, and photo-thermal therapy, but their performance depends critically on the distribution and number of functional groups on their surface. When studying…

We report on image processing techniques and experimental procedures to determine the lattice-site positions of single atoms in an optical lattice with high reliability, even for limited acquisition time or optical resolution. Determining…

In this work we present a new algorithm for data deconvolution that allows the retrieval of the target function with super-resolution with a simple approach that after a precis e measurement of the instrument response function (IRF), the…

Computer Vision and Pattern Recognition · Computer Science 2018-12-07 Sandra Martínez , Oscar E. Martínez

In this work we derive analytic expressions and numerical recipes for finding the effective observed position of sources close enough on sky that their Point Spread Functions (PSF), modelled as Gaussian profiles, overlap. In particularly we…

Solar and Stellar Astrophysics · Physics 2026-03-24 Zephyr Penoyre

Lenses are designed to fulfill Fermats principle such that all light interferes constructively in its focus, guaranteeing its maximum concentration. It can be shown that imaging via an unmodified full pupil yields the maximum transfer…

Lens flare significantly degrades image quality, impacting critical computer vision tasks like object detection and autonomous driving. Recent Single Image Flare Removal (SIFR) methods perform poorly when off-frame light sources are…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Shr-Ruei Tsai , Wei-Cheng Chang , Jie-Ying Lee , Chih-Hai Su , Yu-Lun Liu

Tracking single fluorescent molecules has offered resolution into dynamic molecular processes at the single-molecule level. This perspective traces the evolution of single-molecule tracking, highlighting key developments across various…

Biological Physics · Physics 2026-02-24 Lance W. Q. Xu , Steve Pressé

This paper showcases the theoretical and numerical performance of the Sliding Frank-Wolfe, which is a novel optimization algorithm to solve the BLASSO sparse spikes super-resolution problem. The BLASSO is a continuous (i.e. off-the-grid or…

Numerical Analysis · Mathematics 2018-11-16 Quentin Denoyelle , Vincent Duval , Gabriel Peyré , Emmanuel Soubies
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