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In this paper we study the high-dimensional super-resolution imaging problem. Here we are given an image of a number of point sources of light whose locations and intensities are unknown. The image is pixelized and is blurred by a known…

Optimization and Control · Mathematics 2022-10-19 Bakytzhan Kurmanbek , Elina Robeva

A variety of recent imaging techniques are able to beat the diffraction limit in fluorescence microcopy by activating and localizing subsets of the fluorescent molecules in the specimen, and repeating this process until all of the molecules…

Optics · Physics 2010-08-27 Alexander R. Small

Resonant frequency modulation spectroscopy has been previously used as a highly-sensitive method for measuring the output of cold atom interferometers. Using a detailed model that accounts for optical saturation, laser intensities and…

Atomic Physics · Physics 2024-12-11 Ryan J. Thomas , Samuel R. Legge , Simon A. Haine , John D. Close

We propose a new technique for radio interferometry to obtain super-resolution full polarization images in all four Stokes parameters using sparse modeling. The proposed technique reconstructs the image in each Stokes parameter from the…

Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Xuanyu Tian , Qing Wu , Hongjiang Wei , Yuyao Zhang

By introducing a new operator theory, we provide a unified mathematical theory for general source resolution in the multi-illumination imaging problem. Our main idea is to transform multi-illumination imaging into single-snapshot imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-02-03 Ping Liu , Habib Ammari

Annotation is a major hurdle in the semantic segmentation of microscopy images and volumes due to its prerequisite expertise and effort. This work enables the training of semantic segmentation networks on images with only a single point for…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Shijie Li , Neel Dey , Katharina Bermond , Leon von der Emde , Christine A. Curcio , Thomas Ach , Guido Gerig

Fluorescence microscopy, while being a key driver for progress in the life sciences, is also subject to technical limitations. To overcome them, computational multiplexing techniques have recently been proposed, which allow multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Ashesh Ashesh , Florian Jug

Super-resolution fluorescence microscopy provides unprecedented insight into cellular and subcellular structures. However, going "beyond the diffraction barrier" comes at a price since most far-field super-resolution imaging techniques…

Structured illumination microscopy (SIM) is an important super-resolution based microscopy technique that breaks the diffraction limit and enhances optical microscopy systems. With the development of biology and medical engineering, there…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Xi Cheng , Jun Li , Qiang Dai , Zhenyong Fu , Jian Yang

While super-resolution (SR) methods based on diffusion models exhibit promising results, their practical application is hindered by the substantial number of required inference steps. Recent methods utilize degraded images in the initial…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Yufei Wang , Wenhan Yang , Xinyuan Chen , Yaohui Wang , Lanqing Guo , Lap-Pui Chau , Ziwei Liu , Yu Qiao , Alex C. Kot , Bihan Wen

Optical endoscopy plays a crucial role in minimally invasive medical diagnostics and therapeutic procedures. Nonetheless, state-of-the-art endoscopic zoom objectives are bulky, requiring multi-element lens actuation, which can limit…

We report the experimental super-resolution of pairs of point-like fluorescent sources using a modified image inversion interferometer microscope. The technique is inspired by recent developments in the application of quantum parameter…

Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…

Optics · Physics 2015-10-27 Jeffrey J. Field , David G. Winters , Randy A. Bartels

The extraction of information carried by light plays an increasingly important role in optical communication, imaging, and detection. However, the information can only be successfully extracted when the light pulse is comparably strong,…

Optics · Physics 2026-05-25 Zhen Yang , Zeng-Quan Yan , Li Wang , Xiao-Wei Wang , Ka-Di Zhu , Xian-Min Jin

Coherent interferometric scattering microscopy (iscat) enables nanoparticle tracking on microsecond timescales and with nanometer precision, and has become a key tool in structural and cellular biophysics. The achievable localization…

Compressed sensing theory is slowly making its way to solve more and more astronomical inverse problems. We address here the application of sparse representations, convex optimization and proximal theory to radio interferometric imaging.…

Instrumentation and Methods for Astrophysics · Physics 2015-08-28 Julien N. Girard , Hugh Garsden , Jean Luc Starck , Stéphane Corbel , Arnaud Woiselle , Cyril Tasse , John P. McKean , Jérôme Bobin

We propose a novel technique of microscopy to overcome the effects of both scattering and limitation of the accessible depth due to the objective working distance. By combining Laser Optical Feedback Imaging (LOFI) with Acoustic Photon…

Super-resolution microscopy is crucial for imaging sub-wavelength biological structures. However, most techniques rely on nonlinear saturation or stochastic switching of emitters, limiting imaging speed and increasing phototoxicity. Here,…

Light microscopy as well as image acquisition and processing suffer from physical and technical prejudices which preclude a correct interpretation of biological observations which can be reflected in, e.g., medical and pharmacological…

Quantitative Methods · Quantitative Biology 2019-08-15 Renata Rychtarikova , Georg Steiner , Gero Kramer , Michael B. Fischer , Dalibor Stys