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Recent works on large language models (LLMs) have demonstrated the impact of prompting strategies and fine-tuning techniques on their reasoning capabilities. Yet, their effectiveness on clinical natural language inference (NLI) remains…

Computation and Language · Computer Science 2025-07-08 Mael Jullien , Marco Valentino , Leonardo Ranaldi , Andre Freitas

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Large language models have shown promise in clinical decision making, but current approaches struggle to localize and correct errors at specific steps of the reasoning process. This limitation is critical in medicine, where identifying and…

We present EHRMIND, a practical recipe for adapting large language models (LLMs) to complex clinical reasoning tasks using reinforcement learning with verifiable rewards (RLVR). While RLVR has succeeded in mathematics and coding, its…

Computation and Language · Computer Science 2025-06-02 Jiacheng Lin , Zhenbang Wu , Jimeng Sun

The adaptation of large-scale vision-language models (VLMs) to downstream tasks with limited labeled data remains a significant challenge. While parameter-efficient prompt learning methods offer a promising path, they often suffer from…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Enming Zhang , Jiayang Li , Yanru Wu , Zhenyu Liu , Yang Li

The capacity of large language models (LLMs) to generate honest, harmless, and helpful responses heavily relies on the quality of user prompts. However, these prompts often tend to be brief and vague, thereby significantly limiting the full…

Computation and Language · Computer Science 2025-07-01 Xiaohua Wang , Zisu Huang , Feiran Zhang , Zhibo Xu , Cenyuan Zhang , Qi Qian , Xiaoqing Zheng , Xuanjing Huang

The large language models have achieved superior performance on various natural language tasks. One major drawback of such approaches is they are resource-intensive in fine-tuning new datasets. Soft-prompt tuning presents a…

Computation and Language · Computer Science 2023-10-30 Guoxin Chen , Yiming Qian , Bowen Wang , Liangzhi Li

Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Aishik Konwer , Zhijian Yang , Erhan Bas , Cao Xiao , Prateek Prasanna , Parminder Bhatia , Taha Kass-Hout

Large Language Models (LLMs) have unveiled remarkable capabilities in understanding and generating both natural language and code, but LLM reasoning is prone to hallucination and struggle with complex, novel scenarios, often getting stuck…

Neural and Evolutionary Computing · Computer Science 2025-05-12 Antonio Jimeno Yepes , Pieter Barnard

Prompt engineering is a critical technique in the field of natural language processing that involves designing and optimizing the prompts used to input information into models, aiming to enhance their performance on specific tasks. With the…

Reinforcement learning (RL) with rule-based reward functions has recently shown great promise in enhancing the reasoning depth and generalization ability of vision-language models (VLMs), while maintaining computational efficiency. In spite…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Yizhou Liu , Dingkang Yang , Zizhi Chen , Minghao Han , Xukun Zhang , Keliang Liu , Jingwei Wei , Lihua Zhang

Prompt engineering is critical for the development of LLM-based applications. However, it is usually done manually in a "trial and error" fashion that can be time consuming, ineffective, and sub-optimal. Even for the prompts which seemingly…

Artificial Intelligence · Computer Science 2024-06-11 Weize Kong , Spurthi Amba Hombaiah , Mingyang Zhang , Qiaozhu Mei , Michael Bendersky

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Information Retrieval · Computer Science 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

Large Language Models (LLMs) have demonstrated remarkable capabilities across various tasks, with their performance heavily dependent on the quality of input prompts. While prompt engineering has proven effective, it typically relies on…

Neural and Evolutionary Computing · Computer Science 2025-04-17 Xavier Sécheresse , Jacques-Yves Guilbert--Ly , Antoine Villedieu de Torcy

LLMs have become increasingly capable at accomplishing a range of specialized-tasks and can be utilized to expand equitable access to medical knowledge. Most medical LLMs have involved extensive fine-tuning, leveraging specialized medical…

Medical Vision-Language Models (VLMs) hold immense promise for complex clinical tasks, but their reasoning capabilities are often constrained by text-only paradigms that fail to ground inferences in visual evidence. This limitation not only…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Zheng Jiang , Heng Guo , Chengyu Fang , Changchen Xiao , Xinyang Hu , Lifeng Sun , Minfeng Xu

Evidence-based medicine (EBM) is at the forefront of modern healthcare, emphasizing the use of the best available scientific evidence to guide clinical decisions. Due to the sheer volume and rapid growth of medical literature and the high…

Computation and Language · Computer Science 2025-05-29 Zihan Xu , Haotian Ma , Gongbo Zhang , Yihao Ding , Chunhua Weng , Yifan Peng

Since the emergence of Large Language Models (LLMs), the challenge of effectively leveraging their potential in healthcare has taken center stage. A critical barrier to using LLMs for extracting insights from unstructured clinical notes…

Artificial Intelligence · Computer Science 2024-12-04 Nader Karayanni , Aya Awwad , Chein-Lien Hsiao , Surish P Shanmugam

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Multi-objective optimization problems (MOPs) are ubiquitous in real-world applications, presenting a complex challenge of balancing multiple conflicting objectives. Traditional evolutionary algorithms (EAs), though effective, often rely on…

Neural and Evolutionary Computing · Computer Science 2024-07-29 Yuxiao Huang , Shenghao Wu , Wenjie Zhang , Jibin Wu , Liang Feng , Kay Chen Tan
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