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Cardiovascular disease (CVD) remains one of the leading global health challenges, accounting for more than 19 million deaths worldwide. To address this, several tools that aim to predict CVD risk and support clinical decision making have…
This paper presents a new approach for relatively accurate brain region of interest (ROI) detection from dynamic susceptibility contrast (DSC) perfusion magnetic resonance (MR) images of a human head with abnormal brain anatomy. Such images…
Vertebral compression fractures (VCFs) are a common and potentially serious consequence of osteoporosis. Yet, they often remain undiagnosed. Opportunistic screening, which involves automated analysis of medical imaging data acquired…
Diffuse Correlation Spectroscopy (DCS) allows the label-free investigation of microvascular dynamics deep within living tissue. However, common implementations of DCS are currently limited to measurement depths of $\sim 1-1.5cm$, which can…
This work examines the hypothesis that intravoxel incoherent motion MRI (IVIM) can quantify local cerebral blood flow (qCBF), infarct volume, and define the ischemic penumbra for determination of the perfusion-diffusion mismatch (PWI/DWI)…
Accurate MR signal simulation, including microvascular structures and water diffusion, is crucial for MRI techniques like fMRI BOLD modeling and MR vascular Fingerprinting (MRF), which use susceptibility effects on MR signals for tissue…
Diffusion MRI measures of the human brain provide key insight into microstructural variations across individuals and into the impact of central nervous system diseases and disorders. One approach to extract information from diffusion…
Important applications of advancements in machine learning, are in the area of healthcare, more so for neurological disorder detection. A crucial step towards understanding the neurological status, is to estimate the brain age using…
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due…
Atherosclerotic lesions within carotid and cerebral vessels are likely to influence hemodynamics and manifest into vascular pathologies, including Alzheimers Disease and ischemic stroke. Hemodynamics are influenced by changes in luminal…
The brain perfusion ROI detection being a preliminary step, designed to exclude non-brain tissues from analyzed DSC perfusion MR images. Its accuracy is considered as the key factor for delivering correct results of perfusion data analysis.…
Gender classification has emerged as a crucial aspect in various fields, including security, human-machine interaction, surveillance, and advertising. Nonetheless, the accuracy of this classification can be influenced by factors such as…
Predicting three-dimensional (3D) turbulent flows around bridge piers is a prerequisite for assessing local scour, a primary cause of infrastructure failure. While Computational Fluid Dynamics (CFD) captures complex flow features - such as…
Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…
Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…
Enlarged perivascular spaces (PVS) are increasingly recognized as biomarkers of cerebral small vessel disease, Alzheimer's disease, stroke, and aging-related neurodegeneration. However, manual segmentation of PVS is time-consuming and…
Structures of brain arterial networks (BANs) - that are complex arrangements of individual arteries, their branching patterns, and inter-connectivities - play an important role in characterizing and understanding brain physiology. One would…
Arterial spin labeling perfusion MRI is a noninvasive technique for measuring quantitative cerebral blood flow (CBF), but the measurement is subject to a low signal-to-noise-ratio(SNR). Various post-processing methods have been proposed to…
Imaging the brain vasculature can be critical for cerebral perfusion monitoring in the context of neurocritical care. Although ultrasensitive Doppler (UD) can provide good sensitivity to cerebral blood volume (CBV) in a large field of view,…
Studies have shown marked sex disparities in Coronary Artery Diseases (CAD) epidemiology, yet the underlying mechanisms remain unclear. We explored sex disparities in the coronary anatomy and the resulting haemodynamics in patients with…