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Female athletes are severely understudied in the field of concussion research, despite higher prevalence for injuries and tendency to have longer recovery time. Hormonal fluctuations due to normal menstrual cycle (MC) or hormonal…

Neurons and Cognition · Quantitative Biology 2020-03-03 Yufen Chen , Amy A. Herrold , Virginia Gallagher , Brian Vesci , Jeffrey Mjannes , Leanne R. McCloskey , James L. Reilly , Hans C. Breiter

Understanding human fetal neurodevelopment is of great clinical importance as abnormal development is linked to adverse neuropsychiatric outcomes after birth. Recent advances in functional Magnetic Resonance Imaging (fMRI) have provided new…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Xiangrui Li , Jasmine Hect , Moriah Thomason , Dongxiao Zhu

Diffuse correlation spectroscopy (DCS) analyzes the autocorrelation function of photons scattered by red blood cells, enabling non-invasive, continuous measurement of deep tissue blood flow at the bedside. Multi-layer DCS models (two- and…

Intravoxel Incoherent Motion (IVIM) is a non-contrast magnetic resonance imaging diffusion-based scan that uses a multitude of b-values to measure various speeds of molecular perfusion and diffusion, sidestepping inaccuracy of arterial…

Medical Physics · Physics 2025-01-22 M. Liu , N. Saadat , Y. Jeong , S. Roth , M. Niekrasz , M. Giurcanu , T. Carroll , G. Christoforidis

Functional ultrasound imaging (fUSI) is a cutting-edge technology that measures changes in cerebral blood volume (CBV) by detecting backscattered echoes from red blood cells moving within its field of view (FOV). It offers high…

Neurons and Cognition · Quantitative Biology 2025-08-20 Jared Deighton , Shan Zhong , Kofi Agyeman , Wooseong Choi , Charles Liu , Darrin Lee , Vasileios Maroulas , Vasileios Christopoulos

Cerebral aneurysms are pathological dilations of intracranial arteries that can rupture with devastating consequences, including subarachnoid hemorrhage, stroke, and death. Accumulating evidence indicates that local hemodynamic forces play…

Other Quantitative Biology · Quantitative Biology 2025-05-22 Reza Bozorgpour , Pilwan Kim

Significance: Measuring cerebral blood flow (CBF) is crucial for diagnosing various cerebral diseases. An affordable, wearable, and fiber-free continuous-wave speckle contrast flowmetry (CW-DSCF) technique has been developed for continuous…

Quantitative Methods · Quantitative Biology 2025-02-13 Chaebeom Yeo , Xuhui Liu , Mehrana Mohtasebi , Faezeh Akbari , Faraneh Fathi , Guoqiang Yu

Arterial spin labeling (ASL) allows to quantify the cerebral blood flow (CBF) by magnetic labeling of the arterial blood water. ASL is increasingly used in clinical studies due to its noninvasiveness, repeatability and benefits in…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Cagdas Ulas , Giles Tetteh , Stephan Kaczmarz , Christine Preibisch , Bjoern H. Menze

Cerebrovascular pathology significantly contributes to cognitive decline and neurological disorders, underscoring the need for advanced tools to assess vascular integrity. Three-dimensional Time-of-Flight Magnetic Resonance Angiography (3D…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Abrar Faiyaz , Nhat Hoang , Giovanni Schifitto , Md Nasir Uddin

This study proposes an approach to estimate the functional localization and connectivity from CBF and BOLD signals simultaneously measured by ASL (arterial spin labeling) MRI, especially using exploratory Structural Equation Modeling…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jiancheng Zhuang

Diffuse correlation spectroscopy (DCS) is an emerging noninvasive technique that measures the tissue blood flow, by using near-infrared coherent point-source illumination to detect spectral changes. While machine learning has demonstrated…

Machine Learning · Computer Science 2024-02-02 Xi Chen , Xingda Li

In the realm of cerebrovascular monitoring, primary metrics typically include blood pressure, which influences cerebral blood flow (CBF) and is contingent upon vessel radius. Measuring CBF non-invasively poses a persistent challenge,…

The study of associations between an individual's age and imaging and non-imaging data is an active research area that attempts to aid understanding of the effects and patterns of aging. In this work we have conducted a supervoxel-wise…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Johan Öfverstedt , Elin Lundström , Göran Bergström , Joel Kullberg , Håkan Ahlström

Among the major factors controlling the cerebral blood flow (CBF) - cerebral perfusion pressure, arterial partial pressure of oxygen (PaO2), cerebral metabolism, arterial partial pressure of carbon dioxide (PaCO2), and cardiac output, the…

Medical Physics · Physics 2007-05-23 A. Gersten

Enlarged perivascular spaces (EPVS) in the brain are an emerging imaging marker for cerebral small vessel disease, and have been shown to be related to increased risk of various neurological diseases, including stroke and dementia.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-30 Florian Dubost , Hieab Adams , Gerda Bortsova , M. Arfan Ikram , Wiro Niessen , Meike Vernooij , Marleen de Bruijne

Cerebral aneurysms and arteriovenous malformations are life-threatening hemodynamic pathologies of the brain. While surgical intervention is often essential to prevent fatal outcomes, it carries significant risks both during the procedure…

Machine Learning · Computer Science 2026-03-17 Irem Topal , Alexander Cherevko , Yuri Bugay , Maxim Shishlenin , Jean Barbier , Deniz Eroglu , Édgar Roldán , Roman Belousov

Vascular remodelling is inherent to the pathogenesis of many diseases including cancer, neurodegeneration, fibrosis, hypertension, and diabetes. In this paper, a new susceptibility-contrast based MRI approach is established to analyse…

Accurate identification of brain function is necessary to understand the neurobiology of cognitive ageing, and thereby promote well-being across the lifespan. A common tool used to investigate neurocognitive ageing is functional magnetic…

Neurons and Cognition · Quantitative Biology 2020-05-21 Kamen A. Tsvetanov , Richard N. A. Henson , James B. Rowe

Images with abnormal brain anatomy produce problems for automatic segmentation techniques, and as a result poor ROI detection affects both quantitative measurements and visual assessment of perfusion data. This paper presents a new approach…

Image and Video Processing · Electrical Eng. & Systems 2019-02-19 Svitlana M Alkhimova

Preterm neonates are highly likely to suffer from ventriculomegaly, a dilation of the Cerebral Ventricular System (CVS). This condition can develop into life-threatening hydrocephalus and is correlated with future neuro-developmental…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 Matthieu Martin , Bruno Sciolla , Michaël Sdika , Philippe Quétin , Philippe Delachartre