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The creation of in-silico datasets can expand the utility of existing annotations to new domains with different staining patterns in computational pathology. As such, it has the potential to significantly lower the cost associated with…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dominik Winter , Nicolas Triltsch , Philipp Plewa , Marco Rosati , Thomas Padel , Ross Hill , Markus Schick , Nicolas Brieu

Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to tissue scarcity, assay cost, and workflow constraints.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Jinxi Xiang , Mingjie Li , Siyu Hou , Yijiang Chen , Xiangde Luo , Yuanfeng Ji , Xiang Zhou , Ehsan Adeli , Akshay Chaudhari , Curtis P. Langlotz , Kilian M. Pohl , Ruijiang Li

We report a framework based on a generative adversarial network (GAN) that performs high-fidelity color image reconstruction using a single hologram of a sample that is illuminated simultaneously by light at three different wavelengths. The…

Image and Video Processing · Electrical Eng. & Systems 2019-07-17 Tairan Liu , Zhensong Wei , Yair Rivenson , Kevin de Haan , Yibo Zhang , Yichen Wu , Aydogan Ozcan

Histopathology image analysis is fundamental to digital pathology, with hematoxylin and eosin (H&E) staining as the gold standard for diagnostic and prognostic assessments. While H&E imaging effectively highlights cellular and tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Yao Du , Jiaxin Zhuang , Xiaoyu Zheng , Jing Cong , Limei Guo , Chao He , Lin Luo , Xiaomeng Li

Recent advances in Generative Adversarial Networks (GANs) have led to the creation of realistic-looking digital images that pose a major challenge to their detection by humans or computers. GANs are used in a wide range of tasks, from…

Image and Video Processing · Electrical Eng. & Systems 2020-07-22 Michael Goebel , Lakshmanan Nataraj , Tejaswi Nanjundaswamy , Tajuddin Manhar Mohammed , Shivkumar Chandrasekaran , B. S. Manjunath

The ability to generate synthetic medical images is useful for data augmentation, domain transfer, and out-of-distribution detection. However, generating realistic, high-resolution medical images is challenging, particularly for Full Field…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Dimitrios Korkinof , Tobias Rijken , Michael O'Neill , Joseph Yearsley , Hugh Harvey , Ben Glocker

Due to the absence of fine structure and texture information, existing fusion-based few-shot image generation methods suffer from unsatisfactory generation quality and diversity. To address this problem, we propose a novel feature…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Yingbo Zhou , Zhihao Yue , Yutong Ye , Pengyu Zhang , Xian Wei , Mingsong Chen

The digitization of histology slides has revolutionized pathology, providing massive datasets for cancer diagnosis and research. Self-supervised and vision-language models have been shown to effectively mine large pathology datasets to…

While objects from different categories can be reliably decoded from fMRI brain response patterns, it has proved more difficult to distinguish visually similar inputs, such as different instances of the same category. Here, we apply a…

Human-Computer Interaction · Computer Science 2021-02-23 Rufin VanRullen , Leila Reddy

In many clinical settings, the use of both Computed Tomography (CT) and Magnetic Resonance (MRI) is necessary to pursue a thorough understanding of the patient's anatomy and to plan a suitable therapeutical strategy; this is often the case…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Leonardo Crespi , Samuele Camnasio , Damiano Dei , Nicola Lambri , Pietro Mancosu , Marta Scorsetti , Daniele Loiacono

While Generative Adversarial Networks (GANs) have seen huge successes in image synthesis tasks, they are notoriously difficult to adapt to different datasets, in part due to instability during training and sensitivity to hyperparameters.…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Animesh Karnewar , Oliver Wang

This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Amaya Gallagher-Syed , Elena Pontarini , Myles J. Lewis , Michael R. Barnes , Gregory Slabaugh

Generative Adversarial Networks (GANs) have demonstrated immense potential in synthesizing diverse and high-fidelity images. However, critical questions remain unanswered regarding how quantum principles might best enhance their…

Immunohistochemical (IHC) stains play a vital role in a pathologist's analysis of medical images, providing crucial diagnostic information for various diseases. Virtual staining from hematoxylin and eosin (H&E)-stained whole slide images…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Sitong Liu , Kechun Liu , Samuel Margolis , Wenjun Wu , Stevan R. Knezevich , David E Elder , Megan M. Eguchi , Joann G Elmore , Linda Shapiro

Imbalanced image datasets are commonly available in the domain of biomedical image analysis. Biomedical images contain diversified features that are significant in predicting targeted diseases. Generative Adversarial Networks (GANs) are…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Muhammad Muneeb Saad , Mubashir Husain Rehmani , Ruairi O'Reilly

Generative Adversarial Networks (GANs) have become increasingly powerful, generating mind-blowing photorealistic images that mimic the content of datasets they were trained to replicate. One recurrent theme in medical imaging is whether…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Youssef Skandarani , Pierre-Marc Jodoin , Alain Lalande

Accurate histopathological diagnosis often requires multiple differently stained tissue sections, a process that is time-consuming, labor-intensive, and environmentally taxing due to the use of multiple chemical stains. Recently, virtual…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Jiabo MA , Wenqiang Li , Jinbang Li , Ziyi Liu , Linshan Wu , Fengtao Zhou , Li Liang , Ronald Cheong Kin Chan , Terence T. W. Wong , Hao Chen

Deep learning-based computer-aided diagnosis (CAD) of medical images requires large datasets. However, the lack of large publicly available labeled datasets limits the development of deep learning-based CAD systems. Generative Adversarial…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Muhammad Rafiq , Hazrat Ali , Ghulam Mujtaba , Zubair Shah , Shoaib Azmat

Although two-stage Vector Quantized (VQ) generative models allow for synthesizing high-fidelity and high-resolution images, their quantization operator encodes similar patches within an image into the same index, resulting in a repeated…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Chuanxia Zheng , Long Tung Vuong , Jianfei Cai , Dinh Phung

Tumor segmentation in histopathology images is often complicated by its composition of different histological subtypes and class imbalance. Oversampling subtypes with low prevalence features is not a satisfactory solution since it…