English
Related papers

Related papers: Cross-Domain Image Synthesis: Generating H&E from …

200 papers

The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…

Quantitative Methods · Quantitative Biology 2021-09-21 Pingjun Chen , Muhammad Aminu , Siba El Hussein , Joseph D. Khoury , Jia Wu

Masked image modelling (MIM) is a powerful self-supervised representation learning paradigm, whose potential has not been widely demonstrated in medical image analysis. In this work, we show the capacity of MIM to capture rich semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Piotr Wójcik , Hussein Naji , Adrian Simon , Reinhard Büttner , Katarzyna Bożek

For diagnosing melanoma, hematoxylin and eosin (H&E) stained tissue slides remains the gold standard. These images contain quantitative information in different magnifications. In the present study, we investigated whether deep…

Tissues and Organs · Quantitative Biology 2019-04-15 Peizhen Xie , Ke Zuo , Yu Zhang , Fangfang Li , Mingzhu Yin , Kai Lu

The development of generative models in the past decade has allowed for hyperrealistic data synthesis. While potentially beneficial, this synthetic data generation process has been relatively underexplored in cancer histopathology. One…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Aakash Madhav Rao , Debayan Gupta

In histopathology, tissue sections are typically stained using common H&E staining or special stains (MAS, PAS, PASM, etc.) to clearly visualize specific tissue structures. The rapid advancement of deep learning offers an effective solution…

Image and Video Processing · Electrical Eng. & Systems 2025-04-23 Zizhi Chen , Xinyu Zhang , Minghao Han , Yizhou Liu , Ziyun Qian , Weifeng Zhang , Xukun Zhang , Jingwei Wei , Lihua Zhang

Pathological features are the gold standard for tumor diagnosis, guiding treatment and prognosis. However, standard histopathological process is labor-intensive and time-consuming, while frozen sections have lower accuracy. Dynamic…

Generative adversarial networks (GANs) are unsupervised Deep Learning approach in the computer vision community which has gained significant attention from the last few years in identifying the internal structure of multimodal medical…

Image and Video Processing · Electrical Eng. & Systems 2020-05-22 Nripendra Kumar Singh , Khalid Raza

The large domain discrepancy between faces captured in polarimetric (or conventional) thermal and visible domain makes cross-domain face verification a highly challenging problem for human examiners as well as computer vision algorithms.…

Computer Vision and Pattern Recognition · Computer Science 2018-12-14 He Zhang , Benjamin S. Riggan , Shuowen Hu , Nathaniel J. Short , Vishal M. Patel

The unsupervised training of GANs and VAEs has enabled them to generate realistic images mimicking real-world distributions and perform image-based unsupervised clustering or semi-supervised classification. Combining the power of these two…

Machine Learning · Computer Science 2019-06-18 Abdullah-Al-Zubaer Imran , Demetri Terzopoulos

Multiplex brightfield imaging offers the advantage of simultaneously analyzing multiple biomarkers on a single slide, as opposed to single biomarker labeling on multiple consecutive slides. To accurately analyze multiple biomarkers…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Satarupa Mukherjee , Jim Martin , Yao Nie

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

In the immunohistochemical (IHC) analysis during surgery, frozen-section (FS) images are used to determine the benignity or malignancy of the tumor. However, FS image faces problems such as image contamination and poor nuclear detail, which…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Yiyang Lin , Danling Jiang , Xinyu Liu , Yun Miao , Yixuan Yuan

Multi-focus image fusion technologies compress different focus depth images into an image in which most objects are in focus. However, although existing image fusion techniques, including traditional algorithms and deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-06 Xiebo Geng , Sibo Liua , Wei Han , Xu Li , Jiabo Ma , Jingya Yu , Xiuli Liu , Sahoqun Zeng , Li Chen , Shenghua Cheng

Virtual staining of histopathology images (e.g., H&E-IHC) is an emerging tool in digital pathology, enabling faster and cheaper workflows by synthesizing target stains from routinely acquired slides. Yet, the quality of virtual staining…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Fedor Gubanov , Svetlana Illarionova , Vlad Kozlovskiy , Mikhail Romanov , Yersultan Akhmetov , Aida Akaeva , Vyacheslav Grinevich , Rifat Hamoudi , Maxim Sharaev

Graph convolutional neural networks have shown significant potential in natural and histopathology images. However, their use has only been studied in a single magnification or multi-magnification with late fusion. In order to leverage the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Roozbeh Bazargani , Ladan Fazli , Larry Goldenberg , Martin Gleave , Ali Bashashati , Septimiu Salcudean

Synthesizing a realistic image from textual description is a major challenge in computer vision. Current text to image synthesis approaches falls short of producing a highresolution image that represent a text descriptor. Most existing…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Haileleol Tibebu , Aadil Malik , Varuna De Silva

Understanding the interactions of different cell types inside the immune tumor microenvironment (iTME) is crucial for the development of immunotherapy treatments as well as for predicting their outcomes. Highly multiplexed tissue imaging…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Martin Paulikat , Christian M. Schürch , Christian F. Baumgartner

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

Virtual histology is an emerging field in biomedicine that enables three-dimensional tissue visualization using X-ray micro-computed tomography. However, the method still lacks the specificity of conventional histology, in which parts of…

Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Izabela Horvath , Johannes C. Paetzold , Oliver Schoppe , Rami Al-Maskari , Ivan Ezhov , Suprosanna Shit , Hongwei Li , Ali Ertuerk , Bjoern H. Menze