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The single-cell RNA sequencing (scRNA-seq) technology enables researchers to study complex biological systems and diseases with high resolution. The central challenge is synthesizing enough scRNA-seq samples; insufficient samples can impede…

Genomics · Quantitative Biology 2023-12-25 Yixuan Wang , Shuangyin Li , Shimin DI , Lei Chen

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

Quantitative Methods · Quantitative Biology 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi

We propose a general framework for a collaborative machine learning system to assist bioscience researchers with the task of labeling specific cell identities from microscopic still or video imaging. The distinguishing features of this…

Quantitative Methods · Quantitative Biology 2019-03-25 Greg Bubnis , Steven Ban , Matthew D. DiFranco , Saul Kato

Neural development represents not only an exciting and complex field of study, with ongoing progress, but it also became the epicentre of neuroscience and developmental biology, as it strives to describe the underlying cellular and…

Neurons and Cognition · Quantitative Biology 2014-05-15 Ana M. Mihut , Graham Morgan , Marcus Kaiser

This paper tackles the problem of Cross-view Video-based camera Localization (CVL). The task is to localize a query camera by leveraging information from its past observations, i.e., a continuous sequence of images observed at previous time…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Yujiao Shi , Xin Yu , Shan Wang , Hongdong Li

Human mobility studies how people move to access their needed resources and plays a significant role in urban planning and location-based services. As a paramount task of human mobility modeling, next location prediction is challenging…

Artificial Intelligence · Computer Science 2024-12-30 Zhaoping Hu , Zongyuan Huang , Jinming Yang , Tao Yang , Yaohui Jin , Yanyan Xu

Analyzing the dynamic changes of cellular morphology is important for understanding the various functions and characteristics of live cells, including stem cells and metastatic cancer cells. To this end, we need to track all points on the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Junbong Jang , Kwonmoo Lee , Tae-Kyun Kim

Deep convolutional neural networks (CNNs) have achieved breakthrough performance in many pattern recognition tasks such as image classification. However, the development of high-quality deep models typically relies on a substantial amount…

Computer Vision and Pattern Recognition · Computer Science 2016-05-05 Mengchen Liu , Jiaxin Shi , Zhen Li , Chongxuan Li , Jun Zhu , Shixia Liu

Deep convolutional neural networks (CNNs) have demonstrated impressive performance on visual object classification tasks. In addition, it is a useful model for predication of neuronal responses recorded in visual system. However, there is…

Machine Learning · Statistics 2017-11-15 Qi Yan , Zhaofei Yu , Feng Chen , Jian K. Liu

Vision-language models (VLMs) achieve strong performance on multimodal benchmarks, but may still lack robust control over basic visual operations. We study \textit{line tracing}, where a model must follow a selected visual path through…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Hyesoo Hong , Minsoo Kim , Wonje Jeung , Sangyeon Yoon , Dongjae Jeon , Albert No

Modeling and generating graphs is fundamental for studying networks in biology, engineering, and social sciences. However, modeling complex distributions over graphs and then efficiently sampling from these distributions is challenging due…

Machine Learning · Computer Science 2018-06-26 Jiaxuan You , Rex Ying , Xiang Ren , William L. Hamilton , Jure Leskovec

Multimodal self-supervised learning (MSSL) has emerged as a key paradigm for pretraining geospatial foundation models. However, existing geospatial MSSL methods are mainly designed for static pairs of modalities, such as satellite imagery,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Maria Despoina Siampou , Gengchen Mai , Ni Lao , Jinmeng Rao , Neha Arora , Cyrus Shahabi , Shushman Choudhury

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Filip Lux , Petr Matula

Understanding cell cycle dynamics is crucial for studying biological processes such as growth, development and disease progression. While fluorescent protein reporters like the Fucci system allow live monitoring of cell cycle phases, they…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Louis-Alexandre Leger , Maxine Leonardi , Andrea Salati , Felix Naef , Martin Weigert

Feed-forward convolutional neural networks (CNNs) are currently state-of-the-art for object classification tasks such as ImageNet. Further, they are quantitatively accurate models of temporally-averaged responses of neurons in the primate…

Neurons and Cognition · Quantitative Biology 2018-10-30 Aran Nayebi , Daniel Bear , Jonas Kubilius , Kohitij Kar , Surya Ganguli , David Sussillo , James J. DiCarlo , Daniel L. K. Yamins

Developing safe human-robot interaction systems is a necessary step towards the widespread integration of autonomous agents in society. A key component of such systems is the ability to reason about the many potential futures (e.g.…

Robotics · Computer Science 2019-08-27 Boris Ivanovic , Marco Pavone

Accurate analysis and modeling of renal functions require a precise segmentation of the renal blood vessels. Micro-CT scans provide image data at higher resolutions, making more small vessels near the renal cortex visible. Although…

Image and Video Processing · Electrical Eng. & Systems 2023-05-29 Peidi Xu , Olga Sosnovtseva , Charlotte Mehlin Sørensen , Kenny Erleben , Sune Darkner

Celcomen leverages a mathematical causality framework to disentangle intra- and inter- cellular gene regulation programs in spatial transcriptomics and single-cell data through a generative graph neural network. It can learn gene-gene…

Vessel dynamics simulation is vital in studying the relationship between geometry and vascular disease progression. Reliable dynamics simulation relies on high-quality vascular meshes. Most of the existing mesh generation methods highly…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Dengqiang Jia , Xinnian Yang , Xiaosong Xiong , Shijie Huang , Feiyu Hou , Li Qin , Kaicong Sun , Kannie Wai Yan Chan , Dinggang Shen

Matching cells over time has long been the most difficult step in cell tracking. In this paper, we approach this problem by recasting it as a classification problem. We construct a feature set for each cell, and compute a feature difference…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Quan Wang , Yan Ou , A. Agung Julius , Kim L. Boyer , Min Jun Kim
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