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Two-dimensional (2D) materials have been used extensively in various fields due to their unique physical and chemical properties. Among their diverse applications, field-effect transistor biosensors (bio-FETs) promise a brilliant prospect…

Medical Physics · Physics 2022-08-24 Foad Ghasemi , Abdollah Salimi

We present a method to fabricate double shell structures printed in trans-versal directions using multi-axis fused-deposition-modeling (FDM) robot-ic 3D printing. Shell structures, characterized by lightweight, thin walls, fast buildup, and…

Robotics · Computer Science 2025-01-13 Ioanna Mitropoulou , Amir Vaxman , Olga Diamanti , Benjamin Dillenburger

Tracking of plant cells in images obtained by microscope is a challenging problem due to biological phenomena such as large number of cells, non-uniform growth of different layers of the tightly packed plant cells and cell division.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Md Shazid Islam , Arindam Dutta , Calvin-Khang Ta , Kevin Rodriguez , Christian Michael , Mark Alber , G. Venugopala Reddy , Amit K. Roy-Chowdhury

The biofunctionalization of nanoelectromechanical structures is critical for the development of new classes of biosensors displaying improved performances and higher-level of integration. We propose a modified microcontact printing method…

Mesoscale and Nanoscale Physics · Physics 2015-06-04 Sven Salomon , Thierry Leichle , Denis Dezest , Florent Seichepine , Samuel Guillon , Christophe Thibault , Christophe Vieu , Liviu Nicu

Fluorescence microscopy is a quintessential tool for observing cells and understanding the underlying mechanisms of life-sustaining processes of all living organisms. The problem of extracting 3D shape of mitochondria from fluorescence…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Abhinanda R. Punnakkal , Suyog S Jadhav , Alexander Horsch , Krishna Agarwal , Dilip K. Prasad

4D printing empowers 3D printed structures made of hydrogels, liquid crystals or shape memory polymers, with reversible morphing capabilities in response to an external stimulus. To apply reversible shape-change to stiff lightweight…

The fabrication of multilayered heterostructures is essential for advancing microelectronic and biosensing technologies. Conventional top-down manufacturing techniques are often cost-prohibitive and unsuitable for biomedical applications.…

Chemical Physics · Physics 2025-06-13 Anand Dev Ranjan , Suyash Narayan Amzare , Subhrokoli Ghosh , Ayan Banerjee

Imaging dynamics of cellular morphogenesis with high spatial-temporal resolution in 3D is challenging, due to the low spatial resolution along the optical axis and photo-toxicity. However, some cellular structures are planar and hence 2D…

Quantitative Methods · Quantitative Biology 2020-07-14 Alka Bhat , Linjie Lu , Chen-Ho Wang , Simon Lo Vecchio , Riccardo Maraspini , Alf Honigmann , Daniel Riveline

The use of individual multimode optical fibers in endoscopy applications has the potential to provide highly miniaturized and noninvasive probes for microscopy and optical micromanipulation. A few different strategies have been proposed…

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far…

Fluid Dynamics · Physics 2017-09-19 S. Quint , A. F. Christ , A. Guckenberger , S. Himbert , L. Kaestner , S. Gekle , C. Wagner

This work presents the design and fabrication of simple, polymeric, structure-based optical filters that simultaneously focus light. These filters represent a novel design at the boundary between diffractive optics and metasurfaces that may…

Optics · Physics 2020-09-22 Mansoor A. Sultan , Fatih Balli , Daniel L. Lau , J. T. Hastings

While human technology is ruled by determinism, biological systems exploit a subtle balance of control and stochasticity. This balance, evident in the morphogenesis of textural patterns imprinted on leaves, fur or skin can help hierarchize…

Thin-film self-assembly of three-dimensional (3D) microsystems presents a compelling route to integrate complex functionalities into ultra-compact volumes, yet strategies for incorporating tunable ion-conducting elements remain limited.…

The assembly of arbitrary 3D structures using nano- to micron-scale colloidal building blocks has broad applications in photonics, electronics, and biology. Combining optical tweezers (OT) with two-photon polymerization (TPP) enables 3D…

Research in cell biology is steadily contributing new knowledge about many different aspects of physiological processes like polymerization, both with respect to the involved molecular structures as well as their related function.…

Human-Computer Interaction · Computer Science 2014-07-15 Ivan Kolesar , Julius Parulek , Ivan Viola , Stefan Bruckner , Anne-Kristin Stavrum , Helwig Hauser

Photonic metamaterials are man-made structures composed of tailored micro- or nanostructured metallo-dielectric sub-wavelength building blocks that are densely packed into an effective material. This deceptively simple, yet powerful, truly…

Optics · Physics 2015-05-30 Costas M. Soukoulis , Martin Wegener

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

The membrane curvature of cells and intracellular compartments continuously adapts to enable cells to perform vital functions, from cell division to signal trafficking. Understanding how membrane geometry affects these processes in vivo is…

Microtechnology becomes a versatile tool for biological and biomedical applications. Microwells have been established long but remained non-intelligent up to now. Merging new fabrication techniques and handling concepts with…

Other Computer Science · Computer Science 2008-02-22 E. Jung , D. Manessis , A. Neumann , L. Bottcher , T. Braun , J. Bauer , H. Reichl , B. Iafelice , F. Destro , R. Gambari

Four-dimensional (4D) printing of shape memory polymer (SMP) imparts time responsive properties to 3D structures. Here, we explore 4D printing of a SMP in the submicron length scale, extending its applications to nanophononics. We report a…