The fabrication of multilayered heterostructures is essential for advancing microelectronic and biosensing technologies. Conventional top-down manufacturing techniques are often cost-prohibitive and unsuitable for biomedical applications. Here, we present a bottom-up fabrication method, termed microbubble lithography, which enables the in situ construction of multilayered microstructures through layer-by-layer self-assembly. This technique allows diverse materials to be integrated into coherent heterostructures. We demonstrate the platform's utility by successfully patterning a biomarker and a reporter protein, highlighting its potential for cost-effective and environmentally sustainable sensing applications.
@article{arxiv.2506.10320,
title = {Laser Guided Microbubble Lithography for Multilayer Biophotonic Heterostructures},
author = {Anand Dev Ranjan and Suyash Narayan Amzare and Subhrokoli Ghosh and Ayan Banerjee},
journal= {arXiv preprint arXiv:2506.10320},
year = {2025}
}